| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.62441462 |
| Granulocyte colony stimulating factor ( G CSF ) can elicit different biological responses through interaction with its receptor ( G CSFR ) . 0.62441462^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Molecular cloning of cDNAs for the human granulocyte colony stimulating factor receptor from HL 60 and mapping of the gene to chromosome region 1p32 34 . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| The members of the HRS , including granulocyte macrophage colony stimulating factor receptor ( GM CSF R ) , interleukin 3 receptor ( IL 3 R ) , granulocyte CSF receptor ( G CSF R ) and erythropoietin receptor ( Epo R ) , share a common binding domain and the absence of a tyrosine kinase domain in their cytoplasmic portion . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Expression cloning of a human granulocyte colony stimulating factor receptor : a structural mosaic of hematopoietin receptor , immunoglobulin , and fibronectin domains . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| The receptor for granulocyte colony stimulating factor ( G CSFR ) is a hemopoietic growth factor receptor , which mediates proliferation and differentiation signals . ^^^ Distinct signal transduction through the tyrosine containing domains of the granulocyte colony stimulating factor receptor . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Ligand binding characteristics of the carboxyl terminal domain of the cytokine receptor homologous region of the granulocyte colony stimulating factor receptor . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Detection of the granulocyte colony stimulating factor receptor using biotinylated granulocyte colony stimulating factor : presence of granulocyte colony stimulating factor receptor on CD 34 positive hematopoietic progenitor cells . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Chromosomal gene organization of the human granulocyte colony stimulating factor receptor . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| A hybrid receptor was constructed that contained the extracellular binding domain of the human growth hormone ( hGH ) receptor linked to the transmembrane and intracellular domains of the murine granulocyte colony stimulating factor receptor . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| One segment is conserved in almost all members of the family , and the other is found especially in granulocyte colony stimulating factor receptor , interleukin 2 receptor beta chain , erythropoietin receptor , KH 97 ( a granulocyte / macrophage colony stimulating factor receptor associated molecule ) , and interleukin 3 receptor . gp 130 molecules with mutations in either of these two segments could not transduce growth signal . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Three different mRNAs encoding human granulocyte colony stimulating factor receptor . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Human granulocyte colony stimulating factor receptor expressed on T cell malignant lymphoma cells . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Functional domains of the granulocyte colony stimulating factor receptor . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Assignment of the human granulocyte colony stimulating factor receptor gene ( CSF3R ) to chromosome 1 at region p 35 p34 . 3 . ^^^ The gene for the granulocyte colony stimulating factor ( G CSF ) receptor ( CSF3R ) was localized on the p 35 p34 . 3 region of human chromosome 1 by in situ hybridization using human G CSF receptor cDNA as the probe . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Exogenous expression of human granulocyte colony stimulating factor receptor in a B lineage acute lymphoblastic leukemia cell line : a possible model for mixed lineage leukemia . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| By comparing mRNA levels in c kitBR cells ( enriched for PHSCs ) with those of unfractionated bone marrow , we demonstrated that c kitBR cells contained low or undetectable levels of mRNA for c fms , granulocyte colony stimulating factor receptor , interleukin 5 receptor ( IL 5R ) , and IL 7R . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Point mutations in the conserved box 1 region inactivate the human granulocyte colony stimulating factor receptor for growth signal transduction and tyrosine phosphorylation of p75c rel . ^^^ The human granulocyte colony stimulating factor receptor ( hG CSFR ) belongs to the cytokine receptor superfamily . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Structure and signal transduction of granulocyte colony stimulating factor receptor ] . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Down regulation of the neutrophil G CSFR by several agents including granulocyte macrophage colony stimulating factor ( GM CSF ) , tumour necrosis factor ( TNF ) , lipopolysaccharide ( LPS ) , f met leu phe ( fMLP ) , phorbol ester ( TPA ) and C5a was observed at 37 degrees C but not at 4 degrees C . ^^^ Expression and dynamic modulation of the human granulocyte colony stimulating factor receptor in immature and differentiated myeloid cells . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| The receptor for granulocyte colony stimulating factor ( G CSFR ) and chimeric receptors consisting of the extracellular domain of G CSFR and the transmembrane and cytoplasmic domain of the leukemia inhibitory factor receptor , gp 130 , or c mpl function as homodimeric complexes . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Granulocyte colony stimulating factor ( G CSF ) is a cytokine which regulates proliferation and differentiation of neutrophilic granulocytes , and its receptor ( G CSF R ) is a member of the hemopoietic growth factor receptor family . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Ligand binding domain of granulocyte colony stimulating factor receptor . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Granulocyte colony stimulating factor ( G CSF ) is a glycoprotein that stimulates proliferation and differentiation of progenitor cells of neutrophils by signaling through its receptor ( G CSFR ) . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| A point mutation in the granulocyte colony stimulating factor receptor ( G CSF R ) gene in a case of acute myeloid leukemia results in the overexpression of a novel G CSF R isoform . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| The presence of granulocyte colony stimulating factor receptor ( G CSFR ) in CD34+ hematopoietic progenitors is demonstrated by flow cytometry . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Mutations in the gene for the granulocyte colony stimulating factor receptor in patients with acute myeloid leukemia preceded by severe congenital neutropenia . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Distinct regions of the granulocyte colony stimulating factor receptor are required for tyrosine phosphorylation of the signaling molecules JAK 2 , Stat 3 , and p 42 , p44MAPK . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| The granulocyte colony stimulating factor receptor ( G CSF R ) and growth hormone receptor ( GH R ) belong to the cytokine receptor family and have some similarity in the cytokine receptor homologous ( CRH ) domain of the extracellular region . ^^^ Signal transduction mediated by growth hormone receptor and its chimeric molecules with the granulocyte colony stimulating factor receptor . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Regulation of the differentiation of WEHI 3B D+ leukemia cells by granulocyte colony stimulating factor receptor . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Samples from six of the seven patients at initial disease expressed the granulocyte colony stimulating factor receptor ( G CSFR ) gene . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| On the other hand , neither granulocyte / macrophage colony stimulating factor ( GM CSF ) nor IL 3 induced MPO gene expression , but they inhibited G CSFR mediated MPO gene expression . ^^^ Growth and differentiation signals mediated by different regions in the cytoplasmic domain of granulocyte colony stimulating factor receptor . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| We have generated a hIL 4 responsive murine myeloid cell line ( FDC 4G ) expressing a chimera comprising the extracellular domain of human IL 4R alpha and the intracellular domain of human granulocyte colony stimulating factor receptor ( hG CSFR ) . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Expression of granulocyte colony stimulating factor receptor on CD 10 positive human B cell precursors . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Evidence for the ligand induced conversion from a dimer to a tetramer of the granulocyte colony stimulating factor receptor . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| The granulocyte colony stimulating factor receptor ( G CSFR ) was overexpressed in WEHI 3B D+ myelomonocytic leukemia cells by the transfection of an expression plasmid containing the murine G CSFR cDNA . ^^^ A relatively small portion of the G CSFR is present as the fully mature form on the cell surface as a 150 kDa protein ; this form of the G CSFR binds to granulocyte colony stimulating factor ( G CSF ) . ^^^ Evidence for the glycosylation of the granulocyte colony stimulating factor receptor . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| The granulocyte colony stimulating factor receptor ( GCSFR ) is mainly expressed in neutrophils and their precursor cells . ^^^ Structural analysis of the functional gene and pseudogene encoding the murine granulocyte colony stimulating factor receptor . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Granulocyte colony stimulating factor ( G CSF ) exerts various biological effects through occupancy of its receptor ( G CSFR ) . ^^^ The role of DNA ploidy in the differentiation of WEHI 3B D leukemia cells transfected with the granulocyte colony stimulating factor receptor gene . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| To identify the regions within the cytoplasmic domain of LIFR that initiate signal transduction independently of gp 130 , we constructed a chimeric receptor by linking the extracellular domain of the granulocyte colony stimulating factor receptor ( G CSFR ) to the transmembrane and cytoplasmic domain of human LIFR . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Using murine bone marrow and the granulocyte precusor cell line 32Dc13 , we show that message for the granulocyte colony stimulating factor receptor ( G CSFR ) is upregulated by G CSF in an immediate early fashion that is specific to the differentiation pathway and is antagonized by interleukin 3 . ^^^ Granulocyte colony stimulating factor receptor mRNA upregulation is an immediate early marker of myeloid differentiation and exhibits dysfunctional regulation in leukemic cells . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Granulocyte colony stimulating factor receptor and its related receptors . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Linkage analysis assignment of bovine granulocyte colony stimulating factor receptor ( G CSFR ) to chromosome 3 . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Expression of granulocyte colony stimulating factor receptor increases with differentiation in myeloid cells by a newly devised quantitative flow cytometric assay . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Signal transduction from the granulocyte colony stimulating factor receptor ( G CSF R ) occurs via multiple pathways , one of which involves activation of p21Ras and mitogen activated protein kinase . ^^^ Specific involvement of tyrosine 764 of human granulocyte colony stimulating factor receptor in signal transduction mediated by p145 / Shc / GRB2 or p90 / GRB2 complexes . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Effects of myeloid cell growth factors on alkaline phosphatase , myeloperoxidase , defensin and granulocyte colony stimulating factor receptor mRNA expression in haemopoietic cells of normal individuals and myeloid disorders . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Signal transduction from the granulocyte colony stimulating factor receptor ( G CSF R ) involves the activation of the Janus tyrosine kinase / signal transducer and activator of transcription ( Jak / STAT ) pathway . ^^^ The membrane distal cytoplasmic region of human granulocyte colony stimulating factor receptor is required for STAT 3 but not STAT 1 homodimer formation . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| This stretch is also found in the human interleukin 2 receptor gamma subunit and granulocyte colony stimulating factor receptor genes . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Granulocyte colony stimulating factor receptor signaling involves the formation of a three component complex with Lyn and Syk protein tyrosine kinases . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| The granulocyte colony stimulating factor receptor ( G CSF R ) transduces signals important for the proliferation and maturation of myeloid progenitor cells . ^^^ Distinct cytoplasmic regions of the human granulocyte colony stimulating factor receptor involved in induction of proliferation and maturation . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Deletion mutants of the intracytoplasmic domain of the granulocyte colony stimulating factor receptor ( G CSFR ) have shown that it contains a membrane proximal region which must be conserved to allow the receptor to transduce a mitotic signal , and a C terminal region necessary for transduction of cell differentiation . ^^^ Analysis of granulocyte colony stimulating factor receptor isoforms , polymorphisms and mutations in normal haemopoietic cells and acute myeloid leukaemia blasts . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| The granulocyte colony stimulating factor receptor ( G CSFR ) is a member of the hemopoietic growth factor receptor family . ^^^ Swapping between Fas and granulocyte colony stimulating factor receptor . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| PU . 1 ( Spi 1 ) and C / EBP alpha regulate the granulocyte colony stimulating factor receptor promoter in myeloid cells . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Granulocyte colony stimulating factor receptor ( G CSFR ) , macrophage colony stimulating factor receptor ( M CSFR ) , the alpha and beta chain of IL 2R , IL 4R , IL 7R , IL 8R and 55 , 000 molecular weight TNFR were not detected on fLC . ^^^ Granulocyte colony stimulating factor receptor ( G CSFR ) , macrophage colony stimulating factor receptor ( M CSFR ) , the alpha and beta chain of IL 2R , IL 4R , IL 7R , IL 8R and 55 , 000 molecular weight TNFR were not detected on fLC . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Molecular analysis of the granulocyte colony stimulating factor receptor . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| To determine the contribution of the cytoplasmic domain of the IL 7 receptor alpha chain ( IL 7R alpha ) to activation of STAT proteins , transfectants of the murine pro B cell line BAF 3 were made that express chimeric receptors consisting of the extracellular domain of human granulocyte colony stimulating factor receptor ( G CSF R ) and the transmembrane and intracellular domains of human IL 7R alpha . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| We previously identified a receptor for granulocyte colony stimulating factor ( G CSFR ) on platelet membranes , and reported that G CSF enhanced ADP induced platelet aggregation . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Tec protein tyrosine kinase is involved in the signaling mechanism of granulocyte colony stimulating factor receptor . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Formation of 1 : 1 complex of the cytokine receptor homologous region of granulocyte colony stimulating factor receptor with ligand . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Granulocyte colony stimulating factor ( G CSF ) induces rapid phosphorylation of JAK kinases as well as activation of the p21ras route through interaction with its specific receptor ( G CSF R ) . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Expression of granulocyte colony stimulating factor and granulocyte colony stimulating factor receptor genes in partially overlapping monoclonal B cell populations from chronic lymphocytic leukemia patients . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| The C terminal cytoplasmic region of the granulocyte colony stimulating factor receptor mediates apoptosis in maturation incompetent murine myeloid cells . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| The extracellular region of granulocyte colony stimulating factor receptor in solution has multiple oligomerization states without ligand . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Previously , nonsense mutations in the gene encoding the granulocyte colony stimulating factor receptor ( G CSF R ) have been described in three patients with severe congenital neutropenia ( SCN ) ( Proc Natl Acad Sci USA 1994 ; 91 : 4480 ; New Engl J Med 1995 ; 333 : 487 ) . ^^^ Mutations in the granulocyte colony stimulating factor receptor gene in patients with severe congenital neutropenia . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| We also observed a selective loss of expression of a critical gene target of CCAAT enhancer binding protein alpha , the granulocyte colony stimulating factor receptor . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Activation of the granulocyte colony stimulating factor receptor ( G CSFR ) induces rapid tyrosine phosphorylation of multiple intracellular substrates in proliferating cells and nonproliferating , terminally differentiated neutrophils . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Tyrosine 763 of the murine granulocyte colony stimulating factor receptor mediates Ras dependent activation of the JNK / SAPK mitogen activated protein kinase pathway . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Protein tyrosine kinases in granulocyte colony stimulating factor receptor signal transduction , myeloid cell proliferation , and neutrophil activation . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Granulocyte colony stimulating factor receptor at various differentiation stages of normal and leukemic hematopoietic cells . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Granulocyte colony stimulating factor receptor expression on human transitional cell carcinoma of the bladder . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| To delineate the gp 130 mediated growth signal , we established a series of pro B cell lines expressing chimeric receptors composed of the extracellular domain of the granulocyte colony stimulating factor receptor and the transmembrane and cytoplasmic domains of gp 130 . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| We have generated mice carrying a homozygous null mutation in the granulocyte colony stimulating factor receptor ( G CSFR ) gene . ^^^ Impaired production and increased apoptosis of neutrophils in granulocyte colony stimulating factor receptor deficient mice . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| TPOR belongs to the cytokine receptor group that includes granulocyte colony stimulating factor receptor ( G CSFR ) and erythropoietin receptor ( EPOR ) . ^^^ Soluble thrombopoietin receptor ( Mpl ) and granulocyte colony stimulating factor receptor directly stimulate proliferation of primitive hematopoietic progenitors of mice in synergy with steel factor or the ligand for Flt3 / Flk2 . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Transient transfection experiments with expression vectors for two of the isoforms demonstrated that the 32 . 2 kDa protein is an activator of transcription of granulocyte colony stimulating factor receptor promoter , while the 14 . 3 kDa protein is not . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Solution structure of an extracellular domain containing the WSxWS motif of the granulocyte colony stimulating factor receptor and its interaction with ligand . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| A defined region of the cytoplasmic domain of the granulocyte colony stimulating factor receptor ( G CSF R ) transmits signals for maturation or differentiation of myeloid progenitor cells . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| On the other hand , reactivity was not found for granulocyte colony stimulating factor receptor ( G CSFR ) ( mAb hGCSFR M 1 ) nor macrophage colony stimulating factor receptor ( M CSFR ) ( mAb 7 7A3 17 ) confirming the DC lineage of DDC . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| To monitor the signaling potential of LIFRalpha and gp 130 individually , we constructed chimeric receptors by linking the extracellular domain of granulocyte colony stimulating factor receptor ( GCSFR ) to the transmembrane and cytoplasmic regions of either LIFRalpha or gp 130 . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Neutralising antibodies to the granulocyte colony stimulating factor receptor recognise both the immunoglobulin like domain and the cytokine receptor homologous domain . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Effect of the chimeric soluble granulocyte colony stimulating factor receptor on the proliferation of leukemic blast cells from patients with acute myeloblastic leukemia . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| In this study , the role of granulocyte colony stimulating factor ( G CSF ) in progenitor mobilization was examined using G CSF receptor ( G CSFR ) deficient mice . ^^^ The granulocyte colony stimulating factor receptor is required for the mobilization of murine hematopoietic progenitors into peripheral blood by cyclophosphamide or interleukin 8 but not flt 3 ligand . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| We recently reported that granulocyte colony stimulating factor receptor ( G CSFR ) deficient mice have a severe quantitative defect in granulopoiesis despite which phenotypically normal neutrophils were still detected . ^^^ Interleukin 6 and the granulocyte colony stimulating factor receptor are major independent regulators of granulopoiesis in vivo but are not required for lineage commitment or terminal differentiation . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Clinical relevance of point mutations in the cytoplasmic domain of the granulocyte colony stimulating factor receptor gene in patients with severe congenital neutropenia . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| To this end , we constructed a chimeric cDNA ( GCRER ) encoding the fusion protein between the granulocyte colony stimulating factor receptor ( G CSFR ) and the hormone binding domain ( HBD ) of the estrogen receptor ( ER ) as a selective amplifier gene . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Identification of a ligand binding site on the granulocyte colony stimulating factor receptor by molecular modeling and mutagenesis . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| The granulocyte colony stimulating factor ( G CSF ) / G CSF receptor ( G CSFR ) system in B cell chronic lymphocytic leukemia . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Granulocyte colony stimulating factor receptor mutations in severe chronic neutropenia and acute myeloid leukaemia : biological and clinical significance . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Cytoadhesion signaling through the cytoplasmic domain of CD 34 can not be restored through that of erythropoietin receptor ( EPOR ) or granulocyte colony stimulating factor receptor ( G CSFR ) , suggesting that the cytoplasmic domain of CD 34 is required for its signal transduction of cellular adhesion . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| It is thought that dimerization alone is sufficient for signaling , since monoclonal antibodies ( mAbs ) against the extracellular domain of the GHR elicit proliferation of FDC P 1 cells transfected with a chimeric receptor comprising the extracellular domain of the GHR and the fibronectin and cytoplasmic domains of the murine granulocyte colony stimulating factor receptor . ^^^ We have screened 14 GHR mAbs for proliferative activity against characterized FDC P 1 and BaF B 03 cell lines stably expressing the full length human , rabbit , or rat GHR , or the chimeric human GHR / granulocyte colony stimulating factor receptor , and for transactivation of the c fos promoter and STAT activation . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Expression of granulocyte colony stimulating factor receptor correlates with prognosis in oral and mesopharyngeal carcinoma . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| The membrane distal region of the cytoplasmic domain of human granulocyte colony stimulating factor receptor ( G CSF R ) contains four conserved tyrosine residues : Y 704 , Y 729 , Y 744 , and Y 764 . ^^^ Proliferation signaling and activation of Shc , p21Ras , and Myc via tyrosine 764 of human granulocyte colony stimulating factor receptor . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| The granulocyte colony stimulating factor receptor ( G CSFR ) critically regulates granulopoiesis . ^^^ The granulocyte colony stimulating factor receptor and its role in disorders of granulopoiesis . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Granulocyte colony stimulating factor receptor expression and 11q23 / MLL genotype in childhood acute lymphoblastic leukemia developing during the first 18 months of life . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| The membrane proximal cytoplasmic region of the granulocyte colony stimulating factor receptor ( G CSFR ) is known to be essential for the proliferation signal , with a more distal region being required for the differentiation signal . ^^^ Analysis of the granulocyte colony stimulating factor receptor gene structure using PCR SSCP in myeloid leukemia and myelodysplastic syndrome . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Expression of granulocyte colony stimulating factor ( G CSF ) receptor ( G CSFR ) and in vitro proliferative response to G CSF were investigated by quantitative immunofluorescence and [ 3H ] thymidine uptake , respectively , in a series of acute myeloid leukemias ( AML ) . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| The role of mutations of the granulocyte colony stimulating factor receptor ( G CSFR ) in the pathogenesis of severe congenital neutropenia ( SCN ) and the subsequent development of acute myeloid leukemia ( AML ) is controversial . ^^^ Increased granulocyte colony stimulating factor responsiveness but normal resting granulopoiesis in mice carrying a targeted granulocyte colony stimulating factor receptor mutation derived from a patient with severe congenital neutropenia . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| We show here that the gene encoding the granulocyte colony stimulating factor receptor ( G CSFr ) is specifically upregulated in pre B cells expressing E2A Pbx 1 . ^^^ The gene encoding the granulocyte colony stimulating factor receptor is a target for deregulation in pre B ALL by the t ( 1 ; 19 ) specific oncoprotein E2A Pbx 1 . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Activation of the granulocyte colony stimulating factor receptor ( G CSF R ) leads to tyrosine phosphorylation of multiple cytoplasmic components . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Direct binding of Shc , Grb 2 , SHP 2 and p 40 to the murine granulocyte colony stimulating factor receptor . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Identification of a novel Stat 3 recruitment and activation motif within the granulocyte colony stimulating factor receptor . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| The granulocyte colony stimulating factor receptor ( G CSF R ) activates multiple STAT proteins . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| In the current study , we have identified distinct regions in the granulocyte colony stimulating factor receptor ( G CSFR ) distal to the conserved box 2 motif necessary for mitogenesis , which exert positive and negative influences on growth signaling in Ba / F3 pro B lymphoid cells . ^^^ Phosphatidylinositol 3 ' kinase and SH 2 containing inositol phosphatase ( SHIP ) are recruited by distinct positive and negative growth regulatory domains in the granulocyte colony stimulating factor receptor . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| We hypothesized that at 13 16 wk the abundance of MPO positive cells in the marrow and their scarcity in the liver was the result of production of granulocyte colony stimulating factor ( G CSF ) and its receptor ( G CSF R ) in the marrow and their absence in the liver . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Conditional expression of C / EBPalpha alone in stably transfected bipotential cells triggers neutrophilic differentiation , concomitant with upregulation of the granulocyte specific granulocyte colony stimulating factor receptor and secondary granule protein genes . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Granulocyte colony stimulating factor ( G CSF ) critically affects all stages of granulopoiesis by activating a signaling cascade initiated by dimerization of its receptor ( G CSFR ) . ^^^ Increased expression of the differentiation defective granulocyte colony stimulating factor receptor mRNA isoform in acute myelogenous leukemia . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Perturbed granulopoiesis in mice with a targeted mutation in the granulocyte colony stimulating factor receptor gene associated with severe chronic neutropenia . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Granulocyte colony stimulating factor ( G CSF ) regulates neutrophil production through activation of its cognate receptor , the G CSF R . ^^^ Multiple signals mediate proliferation , differentiation , and survival from the granulocyte colony stimulating factor receptor in myeloid 32D cells . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| In addition , we investigated the expression of p 53 and granulocyte colony stimulating factor receptor ( GCSF R ) to examine the prognostic significance of them in the same samples . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Acquired mutations in the granulocyte colony stimulating factor receptor ( G CSFR ) occur in a subset of patients with severe congenital neutropenia ( SCN ) who develop acute myelogenous leukemia ( AML ) . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Acquired mutations truncating the C terminal domain of the granulocyte colony stimulating factor receptor ( G CSF R ) are found in about 20 % of severe congenital neutropenia ( SCN ) patients , with this cohort of patients predisposed to acute myeloid leukemia ( AML ) . ^^^ Defective internalization and sustained activation of truncated granulocyte colony stimulating factor receptor found in severe congenital neutropenia / acute myeloid leukemia . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| To study the potential role of cytokines and their receptors in hematopoietic cell fate decisions , we used homologous recombination to replace the thrombopoietin receptor gene ( mpl ) with a chimeric construct encoding the extracellular domain of mpl and the cytoplasmic domain of the granulocyte colony stimulating factor receptor ( G CSFR ) . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| In approximately 20 % of cases of severe congenital neutropenia ( SCN ) , mutations are found in the gene encoding the granulocyte colony stimulating factor receptor ( G CSF R ) . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| A functional granulocyte colony stimulating factor receptor is required for normal chemoattractant induced neutrophil activation . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| In order to dissect the contribution of gp 130 and LIFRalpha individually , chimeric molecules consisting of the extracellular domain of the granulocyte colony stimulating factor receptor ( GCSF R ) and various mutant forms of the cytoplasmic domains of gp 130 or LIFRalpha were expressed in embryonic stem ( ES ) cells to test for suppression of differentiation , or in a factor dependent plasma cytoma cell line to assess for induction of proliferation . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Circular permutation of the granulocyte colony stimulating factor receptor agonist domain of myelopoietin . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| On the basis of the previous observations it was hypothesized that the interferon gamma receptor ( IFNgamma r ) and the granulocyte colony stimulating factor receptor ( G CSF receptor ) would be localized in specific sites in the cells of the enamel organ during early amelogenesis . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Granulocyte colony stimulating factor receptor ( G CSFR ) regulates the proliferation and differentiation of neutrophilic progenitor cells through interaction with its cytokine . ^^^ Functional differentiation signals mediated by distinct regions of the cytoplasmic domain of the granulocyte colony stimulating factor receptor . ^^^ Granulocyte colony stimulating factor receptor ( G CSFR ) regulates the proliferation and differentiation of neutrophilic progenitor cells through interaction with its cytokine . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Cells from all samples strongly expressed c kit , granulocyte colony stimulating factor receptor ( G CSFR ) , c fms ( macrophage colony stimulating factor receptor ) , interleukin 3 receptor alpha chain ( IL 3Ralpha ) , and granulocyte macrophage colony stimulating factor receptor alpha chain ( GM CSFRalpha ) , and these data corresponded well to the growth responsiveness to the cytokines . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Granulocyte colony stimulating factor receptor expression on neutrophils of term and preterm neonates with and without signs of infection . ^^^ CONCLUSION : Expression of granulocyte colony stimulating factor receptor on neutrophils is lower than in adults . ^^^ Moreover , granulocyte colony stimulating factor receptor expression seems to be down regulated during neonatal infection . . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| This system involves `` selective amplifier genes ' ' encoding fusion proteins between the granulocyte colony stimulating factor receptor ( Gcr ) and the estrogen receptor ( Er ) . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Previously , a fusion gene encoding a chimeric receptor ( DeltaGCRER ) between the mouse granulocyte colony stimulating factor receptor ( G CSFR ) and the hormone binding domain of rat estrogen receptor was constructed as a ' selective amplifier gene ' . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Additionally , most cells coexpress the stem cell associated transcriptional regulators AML 1 , PU . 1 , GATA 2 and Lmo 2 , as well as the granulocyte colony stimulating factor receptor ( G CSF R ) . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| To anchor a nuclear protein , beta galactosidase with the nuclear localization signal of SV 40 ( nbeta gal ) , within the cytoplasm , nbeta gal was fused to the transmembrane domain of granulocyte colony stimulating factor receptor ( G CSFR ) , a membrane protein . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| To investigate the role of the three extracellular membrane proximal fibronectin type 3 like ( FNIII ) modules of gp 130 and the related receptor for granulocyte colony stimulating factor ( G CSFR ) in cytokine signal transduction we have transfected into murine myeloid M 1 UR21 cells the chimaera ( GR FNIII ) gp 130 , which contains the membrane proximal FNIII modules of the G CSFR on a gp 130 backbone , and its complement , the chimaera ( gp 130 FNIII ) GR . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Association of src kinase Lyn and non src kinase Syk with the granulocyte colony stimulating factor receptor ( G CSFR ) is not abrogated in neutrophils from severe congenital neutropenia patients with point mutations in the G CSFR mRNA . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| MATERIALS AND METHODS : The effects of pH AND pO 2 on granulocyte proliferation , differentiation , and granulocyte colony stimulating factor receptor ( G CSFR ) expression were evaluated using mobilized peripheral blood CD 34 ( + ) cells directed down the granulocytic pathway with stem cell factor , interleukin 3 , interleukin 6 , and G CSF . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| This system involves ' selective amplifier genes ' , that encode fusion proteins between the granulocyte colony stimulating factor receptor ( GCR ) and the hormone binding domain of estrogen receptor ( ER ) . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| HPC mobilization by granulocyte colony stimulating factor ( G CSF ) , cyclophosphamide ( CY ) , or interleukin 8 but not flt 3 ligand is markedly impaired in G CSF receptor deficient ( G CSFR deficient ) mice . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Transient expression of chimeric granulocyte colony stimulating factor receptor ( G CSFR ) gp 130 ( S782A ) receptors resulted in increased cell surface expression in COS 7 cells and increased ability to induce vasoactive intestinal peptide gene expression in IMR 32 neuroblastoma cells when compared with expression of chimeric receptors containing wild type gp 130 cytoplasmic domains . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| In acute myeloid leukemia ( AML ) , granulocyte colony stimulating factor receptor ( G CSFR ) proliferative and maturational signaling pathways are uncoupled . ^^^ Inhibition of granulocyte colony stimulating factor mediated myeloid maturation by low level expression of the differentiation defective class 4 granulocyte colony stimulating factor receptor isoform . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Endotoxin down modulates granulocyte colony stimulating factor receptor ( CD 114 ) on human neutrophils . ^^^ During infection , the development of nonresponsiveness to granulocyte colony stimulating factor ( G CSF ) may be influenced by the down modulation of G CSF receptor ( G CSFR ) by cytokines . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Consistent with a functional importance of this activation , ectopic expression of Stat 1 ( Y701F ) suppressed ATRA induced morphologic differentiation and expression of the monocytic surface markers CD11c and the granulocyte colony stimulating factor receptor . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Evaluation of electrochemiluminescent technology for inhibitors of granulocyte colony stimulating factor receptor binding . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| In the subset of patients with SCN that progresses to AML , acquired mutations in the receptor for granulocyte colony stimulating factor ( G CSF ) have been detected that result in the expression of truncated forms of the G CSF receptor ( G CSFR ) protein . ^^^ Granulocyte colony stimulating factor receptor mutations in severe congenital neutropenia transforming to acute myelogenous leukemia confer resistance to apoptosis and enhance cell survival . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| To explore the mechanisms of granulocyte colony stimulating factor ( G CSF ) induced mobilization , we examined HPC mobilization in mice that are genetically deficient for the G CSF receptor ( G CSFR ) . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| These redesigns resulted in proteins with substantially enhanced stability while retaining wild type levels of biological activity , measured as the ability of the reengineered proteins to stimulate the proliferation of murine myeloid cells transfected with the granulocyte colony stimulating factor receptor . . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| The granulocyte colony stimulating factor receptor ( G CSF R ) forms a tetrameric complex with G CSF containing two ligand and two receptor molecules . ^^^ Identification of ligand binding site 3 on the immunoglobulin like domain of the granulocyte colony stimulating factor receptor . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Progenipoietin 1 : a multifunctional agonist of the granulocyte colony stimulating factor receptor and fetal liver tyrosine kinase 3 is a potent mobilizer of hematopoietic stem cells . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| The carboxyl terminal domain of the granulocyte colony stimulating factor receptor uncouples ribosomal biogenesis from cell cycle progression in differentiating 32D myeloid cells . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Modulation of the binding affinity of myelopoietins for the interleukin 3 receptor by the granulocyte colony stimulating factor receptor agonist . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| We analyzed the immunohistochemical expression of granulocyte colony stimulating factor receptor ( G CSFR ) and platelet derived endothelial cell growth factor ( PD ECGF ) in oral and oropharynx ; 33 samples of normal epithelium , 28 samples of hyperplasia , 16 samples of dysplasia and 58 samples of squamous cell carcinoma . ^^^ Expression of granulocyte colony stimulating factor receptor and platelet derived endothelial cell growth factor in oral and oropharyngeal precancerous lesions . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Granulocyte colony stimulating factor ( G CSF ) downregulates its receptor ( CD 114 ) on neutrophils and induces gelatinase B release in humans . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Retrovirus mediated gene transfer of granulocyte colony stimulating factor receptor ( G CSFR ) cDNA into MDS cells and induction of their differentiation by G CSF . ^^^ In an attempt to find a new strategy that promotes the differentiation of MDS blast cells , we tried retroviral transduction of granulocyte colony stimulating factor receptor ( G CSFR ) into an interleukin 3 dependent MDS cell line , MDS L , since expression of G CSFR is known to be essential for the differentiation of myeloid progenitor cells and this expression is impaired in most MDS cells . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| To define the basis for faulty granulopoiesis in patients with severe congenital neutropenia ( SCN ) , the expression of granulocyte colony stimulating factor receptor ( G CSFR ) in primitive myeloid progenitor cells and their responsiveness to hematopoietic factors were studied . ^^^ Abnormalities of primitive myeloid progenitor cells expressing granulocyte colony stimulating factor receptor in patients with severe congenital neutropenia . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Immunohistochemistry was used to determine the expression of granulocyte colony stimulating factor ( G CSF ) and its receptor ( G CSFR ) in primary ovarian carcinomas . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| The inframe deletion and insertion mutations abrogated the transcriptional activation function of C / EBPalpha on the granulocyte colony stimulating factor receptor promoter . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Concomitantly , there was downregulation of the granulocytic marker granulocyte colony stimulating factor receptor , indicating that the biological activity of Fes was coordinated in a lineage specific manner . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Although granulocyte colony stimulating factor ( G CSF ) has been reported to act on cells of neutrophilic lineage , the expression of receptors for G CSF ( G CSFR ) on human hematopoietic progenitor cells has been unclear . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| The carboxyl terminus of the granulocyte colony stimulating factor receptor , truncated in patients with severe congenital neutropenia / acute myeloid leukemia , is required for SH 2 containing phosphatase 1 suppression of Stat activation . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Here we show that expression of BCR ABL in myeloid precursor cells leads to transcriptional suppression of the granulocyte colony stimulating factor receptor G CSF R ( encoded by CSF3R ) , possibly through down modulation of C / EBPalpha the principal regulator of granulocytic differentiation . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| To clarify the mechanism by which EPO activates Stat 1 and Stat 3 via the EPO receptor ( EPOR ) , a series of chimeric receptors was constructed bearing the extracellular domain of the granulocyte colony stimulating factor receptor linked to the transmembrane domain of EPOR and the full length or several mutants of the cytoplasmic domain of EPOR , and these chimeric receptor complementary DNAs were introduced into UT 7 / EPO cells . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Granulocyte colony stimulating factor ( G CSF ) is the major regulator of granulopoiesis and acts through binding to its specific receptor ( G CSF R ) on neutrophilic granulocytes . ^^^ Tyrosine residues of the granulocyte colony stimulating factor receptor transmit proliferation and differentiation signals in murine bone marrow cells . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Two patients with nonimmune chronic idiopathic neutropenia of adults developing acute myeloid leukemia with aberrant phenotype and complex karyotype but no mutations in granulocyte colony stimulating factor receptor . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| The granulocyte colony stimulating factor receptor ( G CSFR ) regulates the proliferation , differentiation and survival of neutrophilic progenitor cells . ^^^ Distinct region of the granulocyte colony stimulating factor receptor mediates proliferative signaling through activation of Janus kinase 2 and p44 / 42 mitogen activated protein kinase . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Potential redundancy among members of the CCAAT / enhancer binding protein ( C / EBP ) family in myeloid cells is indicated by the ability of C / EBPbeta to replace C / EBPalpha in vivo , by the expression of granulocyte colony stimulating factor receptor ( G CSFR ) on C / EBPalpha ( / ) cell lines , and by our finding that as with C / EBPalpha estrogen receptor ( C / EBPalpha ER ) , either C / EBPbeta ER or C / EBPdelta ER can induce terminal granulopoiesis in 32D cl 3 cells . ^^^ CCAAT / enhancer binding proteins are required for granulopoiesis independent of their induction of the granulocyte colony stimulating factor receptor . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| To elucidate the function of Cb 2 in myeloid leukemia cells , a set of in vitro experiments was carried out using 32D / G CSF R ( granulocyte colony stimulating factor receptor ) cells transfected with exon 1B / exon 2 Cb 2 complementary DNA and a myeloid cell line carrying a virus insertion in Cb 2 ( ie , NFS 78 ) . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| The transcription factor C / EBP alpha regulates early steps of normal granulocyte differentiation since mice with a disruption of the C / EBP alpha gene do not express detectable levels of the granulocyte colony stimulating factor receptor and produce no neutrophils . ^^^ The current study demonstrates that activated Ras enhances the ability of C / EBP alpha to transactivate the granulocyte colony stimulating factor receptor promoter and a minimal promoter containing only C / EBP DNA binding sites . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Recent studies have shown that point mutations in granulocyte colony stimulating factor receptor ( G CSFR ) are involved in the pathogenesis of severe congenital neutropenia ( SCN ) and in the transformation of SCN to acute myelogenous leukemia ( AML ) . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| We have studied the characterization of granulocyte colony stimulating factor receptor ( G CSFR ) in human lymphocytes . ^^^ Characterization of granulocyte colony stimulating factor receptor expressed on human lymphocytes . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| The following tests did not distinguish patients with CMCA from other SDS patients : severity of peripheral cytopenia , fetal hemoglobin levels , percentage of marrow CD34+ cells , colony growth from marrow CD34+ cells , cluster to colony ratio , marrow stromal function , percentage of marrow apoptosis cells , and granulocyte colony stimulating factor receptor expression . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| An activating mutation in the transmembrane domain of the granulocyte colony stimulating factor receptor in patients with acute myeloid leukemia . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| The progenipoietins ( ProGPs ) are a family of genetically engineered chimeric proteins that contain receptor agonist activity for both fetal liver tyrosine kinase 3 and the granulocyte colony stimulating factor receptor . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| In all SCN patients studied no abnormalities of granulocyte colony stimulating factor receptor ( G CSFR ) gene were detected by polymerase chain reaction single strand conformation polymorphism analysis and sequence analysis . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Signaling mechanisms coupled to tyrosines in the granulocyte colony stimulating factor receptor orchestrate G CSF induced expansion of myeloid progenitor cells . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Seven genes , including interleukin 1 receptor antagonist ( IL 1ra ) , IL 1receptor type 2 ( IL 1RII ) , insulin like growth factor binding protein 4 ( IGFBP 4 ) , transforming growth factor beta ( TGF beta ) , granulocyte colony stimulating factor receptor ( G CSFR ) , leukemia inhibitory factor receptor ( LIFR ) , and soluble IL 4 receptor ( sIL 4R ) were selected as probable candidate genes for the trabecular bone sparing effect of estrogen , as the mRNA levels of these genes were highly correlated ( r 2 > 0 . 65 ) to the trabecular BMD . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Granulocyte colony stimulating factor receptor signaling defects from neutropenia to leukemia . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Selective binding and oligomerization of the murine granulocyte colony stimulating factor receptor by a low molecular weight , nonpeptidyl ligand . ^^^ Granulocyte colony stimulating factor regulates neutrophil production by binding to a specific receptor , the granulocyte colony stimulating factor receptor , expressed on cells of the granulocytic lineage . ^^^ Titration microcalorimetry experiments using a soluble murine granulocyte colony stimulating factor receptor construct show that SB 247464 binds to the extracellular domain of the receptor in a zinc ion dependent manner . ^^^ SB 247464 induces internalization of granulocyte colony stimulating factor receptor on intact cells , consistent with a mechanism involving receptor oligomerization . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Granulocyte colony stimulating factor ( G CSF ) induces proliferation , maturation , and functional activities of myeloid progenitors and mature neutrophils through a specific receptor , the G CSF R . ^^^ The carboxy terminal region of the granulocyte colony stimulating factor receptor transduces a phagocytic signal . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Long term follow up of granulocyte colony stimulating factor receptor mutations in patients with severe congenital neutropenia : implications for leukaemogenesis and therapy . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Messenger RNA expression of granulocyte colony stimulating factor receptor isoforms in the fetus . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| To this end , we have developed ' selective amplifier genes ' ( SAGs ) that encode chimeric proteins that are a fusion of granulocyte colony stimulating factor receptor and the steroid binding domain . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| CD34++ cells from 45 patients with myelodysplastic syndrome ( MDS ) and MDS acute myeloid leukaemia ( MDS AML ) were observed by flow cytometry for the expression of granulocyte colony stimulating factor receptor ( G CSFR ) . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| In approximately 20 % of SCN cases , a truncation mutation is found in the cytoplasmic region of the granulocyte colony stimulating factor receptor ( G CSFR ) . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| We have studied the intracellular distribution and internalization kinetics of the granulocyte colony stimulating factor receptor ( G CSF R ) in living cells using fusion constructs of wild type or mutant G CSF R and enhanced green fluorescent protein ( EGFP ) . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Within 3 days of inducing expression of C / EBPalpha , a remarkable neutrophilic differentiation of the KCL 22 blast cells occurred as shown by morphologic changes , induction of expression of CD11b , primary , secondary , and tertiary granule proteins , and granulocyte colony stimulating factor receptor . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Granulocyte colony stimulating factor ( G CSF ) , typically regarded as a hematopoietic growth factor , might also be included because it exists in high concentrations in amniotic fluid , colostrum , and human milk , and because granulocyte CSF receptors ( G CSF R ) are abundantly expressed on the villous enterocytes of the developing intestine . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Deletional mutation of the external domain of the human granulocyte colony stimulating factor receptor in a patient with severe chronic neutropenia refractory to granulocyte colony stimulating factor . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Contribution of the membrane distal tyrosine in intracellular signaling by the granulocyte colony stimulating factor receptor . ^^^ We have evaluated the contribution of intracellular tyrosine residues of the granulocyte colony stimulating factor receptor ( GCSF R ) to its signaling and cellular outcomes . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Recent reports of mutations in the gene encoding this enzyme in some patients with neutropenic syndromes prompted us to investigate whether granulocyte colony stimulating factor ( G CSF ) and its receptor ( G CSFR ) are also substrates for NE . ^^^ Proteolytic cleavage of granulocyte colony stimulating factor and its receptor by neutrophil elastase induces growth inhibition and decreased cell surface expression of the granulocyte colony stimulating factor receptor . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| SOCS 3 is a physiological negative regulator for granulopoiesis and granulocyte colony stimulating factor receptor signaling . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Bone marrow derived primitive CD 34 ( + ) and CD 33 ( + ) / CD34 ( ) progenitor cells from SCN patients evolving to AML , all with mutations in the granulocyte colony stimulating factor receptor ( G CSFR ) gene , demonstrated normal cell survival , whereas more differentiated CD 15 ( + ) / CD33 ( ) / CD34 ( ) cells negative for mutant G CSFR gene , continue to exhibit accelerated apoptosis . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Real time PCR analysis revealed that TPT augmented the expression not only of CD 18 but also of components of superoxide generating NADPH oxidase , p47phox , 2 . 7 fold , and p67phox , 2 . 0 fold , and of granulocyte colony stimulating factor receptor ( G CSFR ) , 3 . 0 fold , whereas various other endocrine disruptors , including parathion , vinclozolin , and bisphenol A , had no such enhancing effects . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| The granulocyte colony stimulating factor receptor ( G CSF R ) transmits signals for proliferation and differentiation of myeloid progenitor cells . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| All pDCs expressed terminal deoxynucleotidyl transferase ( TdT ) , the ETS transcription factor Spi B , the nuclear factor kappaB transcription factor RelB , toll like receptor 9 ( TLR 9 ) , and interferon consensus sequence binding protein ( ICSBP ) / interferon regulatory factor 8 ( IRF 8 ) transcripts ; lacked CD 16 and granulocyte colony stimulating factor receptor ( G CSFR ) ; and were uniformly interleukin 7 receptor alpha ( IL 7Ralpha ( ) ) AA4 . 1 ( Lo ) , CD 27 ( ) , Flk 2 ( Lo ) , c Kit ( ) , DX 5 ( ) , and CD11b ( ) , while CD 4 and CD8alpha were variable . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| AIMS : To discover if human colorectal cancer expresses granulocyte colony stimulating factor receptor ( G CSFR ) and if granulocyte colony stimulating factor ( G CSF ) plays an important part in the development and progression of human colorectal cancer . ^^^ Expression of granulocyte colony stimulating factor receptor in human colorectal cancer . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Transcription factor Tfec contributes to the IL 4 inducible expression of a small group of genes in mouse macrophages including the granulocyte colony stimulating factor receptor . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Bone marrow cells were enriched based on the expression of CD 34 , Kit , and granulocyte colony stimulating factor receptor ( G CSFR ) . ^^^ |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Here , we show that coexpression of the JAK2V617F mutant kinase with a homodimeric Type 1 cytokine receptor , the erythropoietin receptor ( EpoR ) , the thrombopoietin receptor , or the granulocyte colony stimulating factor receptor , is necessary for transformation of hematopoietic cells to growth factor independence and for hormone independent activation of JAK STAT signaling . ^^^ |
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| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| OBJECTIVES : To examine the association of granulocyte colony stimulating factor ( G CSF ) and G CSF receptor ( G CSFR ) expression with increased beta 1 integrin expression and determine the ability of autocrine G CSFR signaling to promote bladder cancer cell adhesion by way of beta 1 integrin . beta 1 integrin is expressed at higher levels in more invasive bladder carcinoma cells and participates in the process of tissue invasion . ^^^ Granulocyte colony stimulating factor receptor signals for beta 1 integrin expression and adhesion in bladder cancer . ^^^ |
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| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| We studied surface expression of granulocyte colony stimulating factor receptor ( G CSFR ) on CD34++ progenitor cells of myelodysplastic patients . ^^^ |
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| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Loss of SHIP and CIS recruitment to the granulocyte colony stimulating factor receptor contribute to hyperproliferative responses in severe congenital neutropenia / acute myelogenous leukemia . ^^^ |
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| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| CCAAT / enhancer binding protein ( C / EBP ) alpha , PU . 1 , granulocyte colony stimulating factor receptor , PR 3 , C / EBP epsilon and lactoferrin were sequentially expressed during neutrophil differentiation but rapidly down regulated during the early erythroid stages . ^^^ |
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| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Unique structural determinants for Stat 3 recruitment and activation by the granulocyte colony stimulating factor receptor at phosphotyrosine ligands 704 and 744 . ^^^ |
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| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| By circumventing IL 6 receptor gp 130 coupled signaling with ectopic expression of the granulocyte colony stimulating factor receptor ( GCSFR ) gp 130 ( 133 ) chimeric receptor , overexpression of Stat 3 induced gammaFBG promoter activity 30 fold in A 549 cells . ^^^ |
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| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| Neutrophil elastase and granulocyte colony stimulating factor receptor mutation analyses and leukemia evolution in severe congenital neutropenia patients belonging to the original Kostmann family in northern Sweden . ^^^ |
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| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| OBJECTIVES : To determine whether granulocyte colony stimulating factor receptor ( G CSFR ) autocrine signaling promotes endothelial cell adhesion and invasion of bladder cancer cells through a beta 1 integrin mediated pathway . ^^^ |
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| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| In order to understand a possible inter relationship between the G CSF and GM CSF induced leukocyte responses and expression levels of receptors for G CSF ( G CSFr ) and GM CSF ( GM CSFr ) , the levels of each receptor and CSF were measured in patients with basophilia ( 8 ) , eosinophilia ( 14 ) and bacterial infection showing neutrophilia ( 12 ) in comparison with normal healthy adults ( 12 ) and children ( 14 ) . ^^^ |
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| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| We analyzed the comparative amounts of granulocyte colony stimulating factor ( G CSFr ) and granulocyte macrophage CSF ( GM CSFr ) receptors expressed on neutrophils and monocytes in measles patients to investigate the role of these CSFrs in the development of leukopenia including neutropenia and monocytopenia in measles . ^^^ |
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| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and Q99062 |
Pubmed |
SVM Score :0.0 |
| NA |
|