| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| The human interleukin 3 receptor ( IL 3R ) is composed of an IL 3 specific alpha subunit ( IL 3R alpha ) and a common beta subunit ( beta c ) that is shared by IL 3 , granulocyte / macrophage colony stimulating factor ( GM CSF ) and IL 5 receptors . ^^^ |
|
| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| We show that neutrophils cultured for 24 hours in granulocyte macrophage colony stimulating factor ( GM CSF ) express mRNA for the IL 3 receptor ( R ) alpha subunit , as shown by RNase protection assays , and IL 3R alpha chain protein , as shown by cytometric analysis using two different specific monoclonal antibodies . ^^^ |
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| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| Whereas the human IL 3R alpha gene is tightly linked with the granulocyte macrophage colony stimulating factor receptor alpha subunit ( GM CSFR alpha ) gene in the pseudoautosomal region of the 10 and Y chromosomes , the mIL 3R alpha gene ( II3ra ) is located in the proximal region of mouse chromosome 14 , separated from the mouse GM CSFR alpha gene , which is on chromosome 19 . ^^^ |
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| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| The human interleukin 3 receptor ( IL 3R ) is a heterodimer that comprises an IL 3 specific alpha chain ( IL 3R alpha ) and a common beta chain ( beta C ) that is shared with the receptors for granulocyte macrophage colony stimulating factor ( GM CSF ) and IL 5 . ^^^ |
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| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| HRMCs were also negative for CD 116 ( granulocyte macrophage colony stimulating factor [ GM CSF ] receptor alpha ) , CD 123 ( interleukin [ IL ] 3Ralpha ) , CD121a ( IL 1R type 1 ) , CD 122 ( IL 2Rbeta ) , and CD 127 ( IL 7R ) and were also found to lack C5aR ( CD 88 ) . ^^^ |
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| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| Cells from all samples strongly expressed c kit , granulocyte colony stimulating factor receptor ( G CSFR ) , c fms ( macrophage colony stimulating factor receptor ) , interleukin 3 receptor alpha chain ( IL 3Ralpha ) , and granulocyte macrophage colony stimulating factor receptor alpha chain ( GM CSFRalpha ) , and these data corresponded well to the growth responsiveness to the cytokines . ^^^ |
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| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| OBJECTIVE : To investigate the iufluence of dexamethasone ( DM ) on expression of interleukin 5 receptor alpha ( IL 5R alpha ) , interleukin 3 receptor alpha ( IL 3R alpha ) , granulocyte macrophage colony stimulating factor receptor alpha ( GM CSFR alpha ) and common beta receptor ( beta cR ) in bronchalveolar lavage fluid ( BALF ) eosinophils in guinea pig asthma model , and to study the mechanism of promotion effect of steroid on eosinophil apoptosis . ^^^ |
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| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| CD 116 [ granulocyte macrophage colony stimulating factor receptor alpha ( GM CSFRalpha ) ] and CD 123 ( IL 3Ralpha ) were expressed on MC precursors on day 14 , but disappeared thereafter . ^^^ |
|
| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| In addition , hybrid receptors composed of the first 104 amino acids ( aa ) of IL 3R alpha joined to aa 118 through 400 of the alpha subunit of the GM CSF receptor ( GM R alpha ) [ IL 3R alpha / GM R alpha ] or the first 118 aa of GM R alpha joined to aa 104 through 378 of IL 3R alpha [ GM R alpha / IL 3R alpha ] failed to bind 125I IL 3 in the presence of the beta subunit . ^^^ |
|
| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| IL 3 transmits its signal through a specific cell surface receptor which consists of a primary binding alpha subunit ( IL 3R alpha ) and a signaling beta subunit that is shared by the IL 5 and GM CSF receptors . ^^^ |
|
| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| Single CD34+ cells from the CD 123 subsets were cultured in a cytokine cocktail of stem cell factor , interleukin 3 ( IL 3 ) , IL 6 , GM CSF , erythropoietin , insulin like growth factor 1 , and basic fibroblast growth factor . ^^^ |
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| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| Exposure to increasing concentrations ( 10 500 U / ml ) of GM CSF was unable to override the suppressive effect of AZT on CFU GM derived colonies , however , treatment in combination with IL 3 ( 10 250 U / ml ) ameliorated the suppressive effects of AZT on CFU GM and on GM CSFR alpha and IL 3R alpha gene expression . ^^^ |
|
| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| In contrast to these findings , eosinophil expression of IL 3R alpha was increased by IL 3 , IL 5 , and GM CSF , whereas GM CSF receptor alpha was down regulated by GM CSF , but was not affected by IL 3 or IL 5 . ^^^ |
|
| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| We found high levels of expression of CD 123 , IL 5R and GM CSF receptors , also found on eosinophils and basophils , and high levels of expression of the receptor for the inflammatory cytokine IL 18 . . ^^^ |
|
| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| In this study , we revealed that blood CD 123 ( hi ) DC in the presence of cytokine ( granulocyte macrophage colony stimulating factor and interleukin 3 ) undergo progressive , step wise maturation through an `` early ' ' stage , delineated by expression of the antigen detected by the new monoclonal antibody CMRF 58 ( CD 123 ( hi ) CMRF 58 ( + ) CD 40 ( ) CD 86 ( ) CD 83 ( ) ) to the `` late ' ' stage with costimulatory antigen expression ( CD 123 ( hi ) CMRF 58 ( + ) CD 40 ( + ) CD 86 ( + ) CD 83 ( + / ) ) . ^^^ |
|
| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| Two DC subsets present in human cerebrospinal fluid ( CSF ) are probably recruited from myeloid ( CD11c ( + ) CD 123 ( dim ) ) and plasmacytoid ( CD11c ( ) CD 123 ( high ) ) blood DC . ^^^ |
|
| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| Four out of seven GBS patients examined prior to treatment with high dose intravenous immunoglobulins ( IvIg ) had elevated numbers of CD 123 ( + ) plasmacytoid DC in the CSF , while both GBS and CIDP patients examined prior to treatment had elevated numbers of CD11c ( + ) myeloid DC in the CSF , as compared to patients with noninflammatory neurological diseases ( OND ) . ^^^ |
|
| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| GMR alpha and IL 3R alpha were expressed on GM CSF and IL 3 responsive cell lines , such as TF 1 and UT 7 , whereas the expression levels were much lower on UT 7E , a GM CSF and IL 3 unresponsive subline of UT 7 . ^^^ |
|
| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| By Southern analysis of somatic cell hybrid panels , pulsed field gel electrophoresis ( PFGE ) , and fluorescence chromosomal in situ hybridization , we have mapped the cloned sequence for the IL 3 receptor alpha ( IL3RA ) to the 10 Y pseudoautosomal region at bands Xp22 . 3 and Yp11 . 3 , near the gene for the alpha subunit of the CSF 2 receptor ( CSF2RA ) . ^^^ |
|
| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04141 and P26951 |
Pubmed |
SVM Score :0.0 |
| NA |
|