| We demonstrate that GILZ interacts in vitro and in vivo with endogenous Raf 1 and that Raf 1 coimmunoprecipitated with GILZ in murine thymocytes treated with DEX . 0.75667346^^^ These data suggest that GILZ contributes , through protein to protein interaction with Raf 1 and the consequent inhibition of Raf MEK ERK activation , to regulating the MAPK pathway and to providing a further mechanism underlying GCH immunosuppression . . 0.60698402^^^ |