| Interacting proteins: O43597 and P04049 |
Pubmed |
SVM Score :1.050413 |
| Furthermore , we show that Spry 2 interacts with Raf 1 in a glutathione S transferase pulldown assay and that this interaction may involve multiple sites . 1.050413^^^ |
|
| Interacting proteins: O43597 and P04049 |
Pubmed |
SVM Score :0.0 |
| We found that SPRY 2 , an inhibitor homologous to SPRY 4 , which was previously shown to suppress Ras / ERK signaling via direct binding to Raf 1 , had reduced expression in WT BRAF cells . ^^^ |
|
| Interacting proteins: O43597 and P04049 |
Pubmed |
SVM Score :0.0 |
| Still , others have emphasized the consequences of the down modulation of endogenous raf inhibitors , such as Sprouty family members ( e . g . , SPRY 2 ) and raf 1 kinase inhibitory protein , in the regulation of the pathway . ^^^ |
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