| Interacting proteins: O15519 and P04049 |
Pubmed |
SVM Score :1.0283107 |
| Interestingly , FLIP was stabilized by MG 132 and interacted with Raf 1 , resulting in enhancement of p 38 signals and cytotoxicity . 1.0283107^^^ |
|
| Interacting proteins: O15519 and P04049 |
Pubmed |
SVM Score :0.0 |
| In turn , this impaired ERK1 / 2 activation in K 8 null hepatocytes is associated with a drastic reduction in c Flip protein , an event that also holds in a K 8 null mouse mammary cell line . c Flip , along with Raf 1 , is part of a K8 / K18 immunoisolated complex from wild type hepatocytes , and Fas stimulation leads to further c Flip and Raf 1 recruitment in the complex . ^^^ |
|
| Interacting proteins: O15519 and P04049 |
Pubmed |
SVM Score :0.0 |
| Fas recruited FLIP interacts with TNF receptor associated factors 1 and 2 , as well as with the kinases RIP and Raf 1 , resulting in the activation of the NF kappaB and extracellular signal regulated kinase ( Erk ) signaling pathways . ^^^ |
|