| Interacting proteins: P02787 and P17936 |
Pubmed |
SVM Score :0.0 |
| There was , however , a small , but significant association between IGFBP 3 concentrations and both serum transferrin and blood hemoglobin concentrations . ^^^ |
|
| Interacting proteins: P02787 and P17936 |
Pubmed |
SVM Score :0.0 |
| MEASUREMENTS AND MAIN RESULTS : In addition to daily routine laboratory studies , the visceral proteins prealbumin , retinol binding protein , and transferrin , and nitrogen balance were measured twice a week , as were the thyroid hormones triiodothyronine , thyroxine , and thyroid stimulating hormone , plasma insulin levels , and the insulin like growth factor ( IGF ) 1 binding proteins IGF BP 1 and IGF BP 3 . ^^^ |
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| Interacting proteins: P02787 and P17936 |
Pubmed |
SVM Score :0.0 |
| Plasma concentrations of albumin , total protein , transferrin , leptin IGF 1 , IGFBP 3 and the protein catabolic rate remained unchanged . ^^^ |
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| Interacting proteins: P02787 and P17936 |
Pubmed |
SVM Score :0.0 |
| The Ati Negritos showed lower growth hormone binding protein ( GHBP ) , insulin like growth factor 1 ( IGF 1 ) , insulin like growth factor binding protein 3 ( IGFBP 3 ) , acid labile subunit ( ALS ) , zinc , albumin , ferritin , iron , iron saturation and much higher insulin like growth factor binding protein 2 ( IGFBP 2 ) and plasma transferrin concentrations . ^^^ |
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| Interacting proteins: P02787 and P17936 |
Pubmed |
SVM Score :0.0 |
| Transferrin binds insulin like growth factors and affects binding properties of insulin like growth factor binding protein 3 . ^^^ |
|
| Interacting proteins: P02787 and P17936 |
Pubmed |
SVM Score :0.0 |
| To this goal , in 22 patients with burn [ BURN , age ( mean+ / SE ) : 46 . 5+ / 3 . 4 yr , BMI : 25 . 0+ / 0 . 8 kg / m2 , % burn surface area : 26 . 0+ / 3 . 0 % , ROI score : 0 . 22+ / 0 . 1 ] we evaluated IGF 1 , IGF binding protein ( IGFBP 3 ) , GH , GH binding protein ( GHBP ) , pre albumin ( pre A ) , albumin ( A ) and transferrin ( TRA ) levels on days 1 , 3 , 7 , 14 and 28 after intensive care unit ( ICU ) admission . ^^^ |
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| Interacting proteins: P02787 and P17936 |
Pubmed |
SVM Score :0.0 |
| RESULTS : The serum levels of GH , IGF 1 , IGFBP 3 , serum prealbumin and transferrin in rhGH treatment group were evidently higher than those in control groups at 10 and 17 PBDs ( P < 0 . 05 approximately 0 . 01 ) . ^^^ |
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| Interacting proteins: P02787 and P17936 |
Pubmed |
SVM Score :0.0 |
| Components of the IGF 1 system ( total and free IGF 1 ; IGFBP 1 , 3 , and ALS ; nonternary IGF 1 and IGFBP 3 ) , biomarkers of metabolic and nutritional status ( transferrin , ferritin , prealbumin , glucose , free fatty acids , glycerol , beta hydroxybutyrate ) , and body composition were measured in 12 men ( 22 + / 3 yr , 87 + / 8 kg , 183 + / 7 cm , 20 + / 5 % body fat ) on days 1 , 3 , and 4 during a control and experimental ( Exp ) period . ^^^ |
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| Interacting proteins: P02787 and P17936 |
Pubmed |
SVM Score :0.0 |
| We hypothesized that IGFBP 3 is first secreted then taken up again into cells and that its internalization could occur via binding to transferrin or caveolin . ^^^ Nuclear localization of exogenously added IGFBP 3 was rapid , occurring within 15 min , inhibited by co incubation and extracellular sequestration with IGF 1 , and dependent on the transferrin binding C terminal peptide region of IGFBP 3 . ^^^ Co immunoprecipitation assays confirmed that IGFBP 3 binds transferrin but not directly to the transferrin receptor ( TfR 1 ) ; however , transferrin binds TfR 1 and a ternary complex is formed . ^^^ Co treatment with anti transferrin receptor antibody and cholesterol depletion agents completely abolished endogenous and exogenous IGFBP 3 uptake . ^^^ |
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| Interacting proteins: P02787 and P17936 |
Pubmed |
SVM Score :0.0 |
| Mass spectrometry and Western blotting revealed the presence of IGFBP 3 , IGFBP 5 , transferrin , plasminogen , prekallikrein , antithrombin 3 , and the soluble IGF II / mannose 6 phosphate receptor in the eluate . ^^^ IGF 2 ligand blotting and surface plasmon resonance spectrometry have been used to identify plasminogen as a novel high affinity IGF 2 binding protein capable of binding to IGFBP 3 with 50 fold higher affinity than transferrin . ^^^ Size exclusion chromatography of the IGF 2 matrix eluate revealed that transferrin , plasminogen , and the IGFBP 3 protease are present in different high molecular mass complexes of > or =440 kDa . ^^^ |
|
| Interacting proteins: P02787 and P17936 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P02787 and P17936 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P02787 and P17936 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P02787 and P17936 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P02787 and P17936 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P02787 and P17936 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P02787 and P17936 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P02787 and P17936 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P02787 and P17936 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P02787 and P17936 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P02787 and P17936 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P02787 and P17936 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P02787 and P17936 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P02787 and P17936 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P02787 and P17936 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P02787 and P17936 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P02787 and P17936 |
Pubmed |
SVM Score :0.0 |
| NA |
|