| Interacting proteins: P05546 and P02787 |
Pubmed |
SVM Score :0.0 |
| The effects of the stoichiometric inhibitors tissue factor pathway inhibitor ( TFPI ) , antithrombin 3 ( AT 3 ) and heparin cofactor 2 ( HC 2 ) on thrombin generation were evaluated in a reaction system composed of coagulation factors VIIa , 10 , 9 , 8 , and 5 and prothrombin initiated by tissue factor ( TF ) and phospholipids . ^^^ |
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| Interacting proteins: P05546 and P02787 |
Pubmed |
SVM Score :0.0 |
| An increased risk of venous thrombotic disease in HIV infected patients could be explained by the presence of a hypercoagulable state , characterised by an increase in procoagulant factors , such as endothelial TF expression and thrombogenic properties of microparticles , and a decrease in anticoagulant factors , including AT 3 , HC 2 and the protein C pathway . ^^^ |
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| Interacting proteins: P05546 and P02787 |
Pubmed |
SVM Score :0.0 |
| Recent studies suggest that dermatan sulphate which catalyzes thrombin inhibition by heparin cofactor 2 ( HCII ) , can inhibit TF and TG as effectively as HEP . ^^^ |
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| Interacting proteins: P05546 and P02787 |
Pubmed |
SVM Score :0.0 |
| These `` antithrombotic ' ' features of the endothelium encompass antiaggregatory mechanisms ( formation and release of prostacyclin [ PGI 2 ] , adenosine , EDRF [ NO ] , degradation of ADP and other nucleotides mediated by ecto nucleotidases ) as well as anti coagulatory properties ( formation and release of `` tissue factor pathway inhibitor ' ' [ TFPI ] , which blocks the coagulation cascade by joining F Xa , TF and F VIIa into an inactive complex , thrombomodulin thrombin induced activation of protein C , which , together with protein S , inactivates F Va and F VIIIa , thereby attenuating further generation of thrombin , and the heparan sulfate enhanced activation of antithrombin 3 and heparin cofactor 2 ) . ( ABSTRACT TRUNCATED AT 250 WORDS ) . ^^^ |
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| Interacting proteins: P05546 and P02787 |
Pubmed |
SVM Score :0.0 |
| NA |
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| Interacting proteins: P05546 and P02787 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P05546 and P02787 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P05546 and P02787 |
Pubmed |
SVM Score :0.0 |
| NA |
|