Pubmed abstracts for Protein-Protein Interaction search result :


Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
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Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.87304125
In contrast to the association of fibronectin with integrins , the interaction with 5 ' nucleotidase does not require divalent metal ions . 0.87304125^^^
Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
Polyclonal and monoclonal antibodies raised against chicken gizzard 5 ' nucleotidase were tested in adhesion assays of embryonic chicken fibroblasts ( CEF ) for their ability to interfere with the adhesion process of these cells on either laminin or fibronectin substrata . ^^^ The initial attachment process of CEF on fibronectin and laminin substrata was not influenced by preincubating these cells with antibodies against chicken gizzard 5 ' nucleotidase . ^^^
Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
The ecto enzyme 5 ' nucleotidase isolated from chicken gizzard has previously been shown to be a potent ligand of two glycoproteins of the extracellular matrix , namely fibronectin and laminin . ^^^ In contrast , ecto 5 ' nucleotidase was only faintly detectable on cells surrounded by a matrix expressing high levels of fibronectin . ^^^
Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
Modulation of 5 ' nucleotidase activity in plasma membranes and intact cells by the extracellular matrix proteins laminin and fibronectin . ^^^ Modulation of 5 ' nucleotidase activity by the extracellular matrix proteins fibronectin , laminin and their fragments has been studied in plasma membrane preparations as well as in intact BCS TC 2 and Rugli cells . ^^^
Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
Monoclonal antibodies against 5 ' nucleotidase from a human pancreatic tumor cell line : their characterization and inhibitory capacity on tumor cell adhesion to fibronectin substratum . ^^^ PTN 63 reduced the attachment to fibronectin substratum of a human pancreatic adenocarcinoma tumor cell line possessing a high amount of plasma membrane bound ecto 5 ' nucleotidase , but had no effect on a cell line lacking the membrane bound AMPase . ^^^
Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
Previous studies have shown that 5 ' nucleotidase , an ectoenzyme from chicken gizzard , interacts specifically with laminin and fibronectin , two glycoproteins of the extracellular matrix . ^^^
Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
Evidence for the direct interaction of chicken gizzard 5 ' nucleotidase with laminin and fibronectin . ^^^ The ectoenzyme 5 ' nucleotidase purified from chicken gizzard is shown to specifically interact with laminin and fibronectin , components of the extracellular matrix , by a number of different techniques : ( 1 ) cosedimentation with laminin by sucrose gradient centrifugation ; ( 2 ) affinity adsorption to both laminin and fibronectin Sepharose 4 B ; ( 3 ) specific binding to both laminin and fibronectin dotted onto cellulose filters ; and ( 4 ) monoclonal antibodies against 5 ' nucleotidase are shown to interfere with the interaction of 5 ' nucleotidase with laminin and fibronectin . ^^^
Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
The extracellular matrix proteins laminin and fibronectin modify the AMPase activity of 5 ' nucleotidase from chicken gizzard smooth muscle . ^^^ Laminin and fibronectin , but not collagen , affect the AMPase activity of the purified transmembrane protein 5 ' nucleotidase . ^^^
Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
Immunoreactivity for 5 ' nucleotidase was essentially absent from fibroblasts that could be identified by their immunoreactivity for fibronectin . ^^^
Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
The proteins were ( 1 ) seminal vesicle derived fibronectin , ( 2 ) prostate derived 5 ' nucleotidase and ( 3 ) a hitherto unidentified 100 kD membrane protein from epididymis , seminal vesicle and prostate . 1 . ^^^ These findings point to a possible post testicular regulatory function of seminal fibronectin . 2 . 5 ' Nucleotidase ( 5 ' NT ) is an enzyme that hydrolyzes nucleotides such as AMP or IMP into inorganic phosphate and the respective nucleoside . ^^^
Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
The myoblast cell surface activity of ecto 5 ' nucleotidase was stimulated by a laminin substrate , whereas fibronectin and gelatin did not increase the AMPase activity of ecto 5 ' nucleotidase . ^^^
Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
Flow cytometry analyses and immunocytochemistry stain showed that placental MSC was a homogeneous cell population devoid of hematopoietic cells , which uniformly expressed CD 29 , CD 44 , CD 73 , CD 105 , CD 166 , laminin , fibronectin and vimentin while being negative for expression of CD 31 , CD 34 , CD 45 and alpha smooth muscle actin . ^^^
Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
Niacinamide ( 750 mg / kg , ip ) pretreatment ( 30 min ) reduced the incidence of MV ( 40 % ) and FN ( 45 % ) at 24 h , but did not reduce IE , EN , or PE . ^^^
Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
In addition , conventional en face sections were double labeled using combinations of phalloidin and antibodies to fibronectin and alpha 5 beta 1 integrin . ^^^
Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
En face confocal microscopy of arterial segments revealed that soluble fibronectin had polymerized on the alpha5beta1 integrin expressing SMCs of the luminal surface of the injured arterial neointima , but not on the alpha5beta1 integrin negative neointimal SMCs below this or on the endothelial cells of uninjured arteries . ^^^
Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
Measurements of the fetal nuclear ( FN ) elliptical angles ( anterior and posterior ) , embryonic nuclear ( EN ) anterior posterior ( A P ) axial thickness , and the number of EN fiber cell membrane folds over 20 microns were compared . ^^^ RESULTS : Diabetic lenses with nuclear cataract exhibited smaller FN elliptical angles , smaller EN axial thicknesses , and larger numbers of EN compaction folds than their non cataractous diabetic counterparts . ^^^
Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
The comparison of TPN and EN patients revealed differences in the distribution patterns of the ECM proteins laminin , fibronectin , and tenascin along the crypt villus axis . ^^^
Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
Evidence is presented here that a unique N terminal amino acid sequence of YadA ( pstb ) , which is absent in YadA ( ent ) , acts as an `` uptake domain ' ' by mediating tight binding to fibronectin bound on alpha ( 5 ) beta ( 1 ) integrin receptors , which are crucial for initiating the entry process . ^^^ Deleting this motif in YadA ( pstb ) generated all features of the YadA ( ent ) protein , i . e . , the molecule lost its adhesiveness to fibronectin and its invasiveness , but gained adhesion potential to collagen and laminin . ^^^
Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
Nucleotide ( nt ) and deduced amino acid ( aa ) sequences revealed the characteristic primary structure , which begins with a signal peptide and TN unique sequences , follows with 14 1 / 2 epidermal growth factor ( EGF ) like repeats and 13 fibronectin type 3 repeats ( FN repeat ) , and concludes with fibrinogen homologous sequences . ^^^
Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
To elucidate the relationship between Fn plasma levels , Fn rich cryoprecipitate infusion , and possible low grade DIC in these patients , we measured platelet count , prothrombin complex ( NT ) , fibrinogen , F 5 , F VIIIR : Ag , F 8 : C , F 12 , plasminogen ( Plg ) , antiplasmin ( AP ) , antithrombin 3 ( AT ) , kallikrein inhibiting activity ( KI ) and spontaneous proteolytic activity ( SPA ) . ^^^ Low levels ( p less than . 001 ) were found for Fn , NT , F 12 , AT and for the ratio F 8 : C / F CIIIR : Ag . ^^^
Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
We wanted to : compare some `` conventional ' ' DIC variables in the ICU ( platelet count , prothrombin complex = NT , FDP ) to additional variables : Fibronectin ( Fn ) , fibrinogen ( Fg ) , F 5 , FVIII R : Ag , F 8 : C activity , F 12 , plasminogen ( Plg ) , antiplasmin ( AP ) , antithrombin ( AT ) , kallikrein inhibiting activity ( KI ) and spontaneous proteolytic activity ( SPA ) : study the effects of cryoprecipitate or plasma infusion on three variables . ^^^ Fn , NT , 12 , Plg , AP and AT were markedly low ( p less than . 001 ) . ^^^
Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
Male Wistar rats were treated with pethidine ( PT ) or fentanyl ( FN ) subcutaneously ( sc ) followed by intrathecal ( ith ) non analgesic doses of methionine ( MENK ) or leucine enkephalin ( LENK ) , neurotensin , ( NT ) , substance P ( SP ) or cholecystokinin octapeptide 26 33 ( CCK 8 ) . ^^^ SP , CCK 8 and NT augmented FN analgesia . ^^^
Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
Correlations between numbers of ESFPs and turns , NTs and phases , NTs and turns , and NT and main spike duration for the MSF and CN MUP recordings , respectively , were statistically significant ( P < 0 . 05 ) . ^^^
Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
We have analyzed immunohistochemically and immunochemically the expression of VLA 3 integrin and its known ligands , namely , laminin ( LM ) , fibronectin ( FN ) , collagen type 4 ( Coll 4 ) , nicein ( NIC ) , and entactin / nidogen ( ENT ) , in lung tumors of various histological types . alpha 3 beta 1 was detectable in normal bronchial epithelium and along basement membranes of alveolar walls . ^^^ While the expression of both alpha 3 beta 1 and ligands LM , FN , Coll 4 , and Ent correlated in NSCLC with the presence of basement membranes , FN was the only ligand detectable in the stroma of SCLCs . ^^^
Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
The polymerase chain reaction ( PCR ) procedure has been utilised to clone , from mouse genomic DNA , a region of the fibronectin ( FN ) encoding gene ( FN ) which includes the 5 ' flanking nucleotide ( nt ) sequences . ^^^ The mouse promoter nt sequence shows high homology to the rat and human FN promoters , including consensus nt sequences for several DNA binding transcription factors . . ^^^
Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
Correlations of MUAP amplitude ( r = 0 . 767 ) , number of turns ( r = 0 . 839 ) , and number of negative going positive going turn ( NT ) ( r = 0 . 737 ) between the CN and MSF recordings were statistically significant ( p < 0 . 001 ) . ^^^
Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
NT 3 was delivered by grafting impregnated fibronectin ( 500 ng / ml ; NT group ) in the axotomised sciatic nerve . ^^^ By d 30 , exogenous NT 3 and nerve graft attenuated the upregulation of NPY ( P < 0 . 05 for NT and NG vs FN ) . ^^^ The mean cell diameter of NPY immunoreactive neurons was significantly smaller in the NT 3 group ( P < 0 . 05 for NT vs FN and NG ) suggesting a differential influence of NT 3 on larger neurons . ^^^
Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
We observed aligned fibrillar structures of fibronectin on NT not only on the basal site but interestingly , also on the apical cell surface . ^^^
Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
The FN mRNA expression of the SD + HG group was 0 . 749 , significantly higher than those of the FP + HG and NT + HP groups ( 0 . 463 and 0 . 475 respectively , both P < 0 . 01 ) . ^^^ The FN protein expression of the SD + HG group was 659 , 550 , significantly higher than those of the FP + HG and NT + HG groups ( 342 , 354 and 340 , 428 respectively , both P < 0 . 01 ) . ^^^
Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
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Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
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Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
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Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
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Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
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Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
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Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
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Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
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Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
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Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
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Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
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Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
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Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
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Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
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Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
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Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
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Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
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Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
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Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
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Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
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Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
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Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
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Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
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Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
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Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
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Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
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Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
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Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
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Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
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Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
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Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
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Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
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Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
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Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
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Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
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Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
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Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
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Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
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Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
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Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
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Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
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Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
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Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
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Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
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Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
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Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
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Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
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Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
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Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
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Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
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Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
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Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
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Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
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Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
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Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
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Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
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Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
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Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
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Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
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Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
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Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
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Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
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Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
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Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
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Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
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Interacting proteins: P21589 and P02751 Pubmed SVM Score :0.0
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