| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| Fibroblasts plated on a mixed substrate of FN and TN , but not on FN alone , upregulated synthesis of four genes : collagenase , stromelysin , the 92 kDa gelatinase , and c fos . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| To test the role of the fibronectin type 2 like repeats in elastolytic activity , we expressed the 92 kDa gelatinase CD with its fibronectin type 2 like repeats ( 92 CD / FN ) in yeast . 92 CD / FN degraded insoluble elastin with activity comparable to full length 92 kDa gelatinase . 92 and 72 CDs lacking the fibronectin type 2 like repeats did not bind elastin , whereas the parent enzymes and 92 CD / FN did bind elastin . ^^^ Furthermore , recombinant 92 kDa fibronectin type 2 like repeats inhibited binding of the 92 kDa gelatinase to elastin . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| PDL cells exposed to intact FN did not express the proteinases induced by the 120 kDa fragment but did express 92 kDa gelatinase and the 20 kDa proteinase inhibitor . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| Further , monoclonal antibodies to alpha 5 or beta 1 integrin block the bFGF induced adhesion to fibronectin . bFGF also stimulated U 937 cell secretion of a 92 kDa gelatinase which was identified by immunoblot to be gelatinase B . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| Alanine scanning mutagenesis and functional analysis of the fibronectin like collagen binding domain from human 92 kDa type 4 collagenase . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| Expression of 92 kDa type 4 collagenase could not be induced by peptides ( GRGDS , GRGES ) , proteins ( fibronectin , laminin , fibrinogen , albumin ) , or antibodies to fibronectin . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| Human 92 kDa type 4 collagenase : functional analysis of fibronectin and carboxyl end domains . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| To elucidate the origin of gelatinase B in cyst fluids of the MCAS 3 tumors , murine skin fibroblasts ( MSF ) were isolated from a subcutaneous tumor in a nude mouse and tested for their proteinase secretion in culture . ^^^ MSF cells , which secreted some gelatinase A and gelatinase B , were induced to secrete high levels of both enzymes , especially gelatinase B , by co cultivation with MCAS 3 cells . ^^^ In addition , gelatinase A activity was induced by incubation of MSF cells with the conditioned medium of either MCAS 3 or OVISE 3 cells , whereas gelatinase B was induced only with that of MCAS 3 . ^^^ Although cytokines or growth factors such as IL 1 beta , TGF beta 1 , TNF alpha or EGF stimulated the secretion of gelatinases A and B from MSF cells , their effects on gelatinase B activity were far less than that of the MCAS 3 conditioned medium . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| The fibronectin like domain is required for the type 5 and 11 collagenolytic activity of gelatinase B . ^^^ These data indicate that the fibronectin like domain of gelatinase B is an important determinant of the enzyme ' s fibrillar collagen substrate specificity . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| Immunohistochemical analysis for the detection of fibronectin , collagen 1 , 3 , and 4 , smooth muscle actin , MMP 1 ( interstitial collagenase ) , 2 ( gelatinase A ) , and 9 ( gelatinase B ) , and TIMP 2 , and in situ hybridization for the detection of MMP 9 mRNA were performed . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| Fibronectin upregulates gelatinase B ( MMP 9 ) and induces coordinated expression of gelatinase A ( MMP 2 ) and its activator MT 1 MMP ( MMP 14 ) by human T lymphocyte cell lines . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| Differential induction of gelatinase B ( MMP 9 ) and gelatinase A ( MMP 2 ) in T lymphocytes upon alpha ( 4 ) beta ( 1 ) mediated adhesion to VCAM 1 and the CS 1 peptide of fibronectin . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| Furthermore , the secreted enzyme appears structurally distinct from known gelatinase Bs and the activated enzyme can cleave fibronectin , which is not a substrate for mammalian gelatinase B . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| Incubation of purified human monocytes in serum free medium with CGP 42112 enhanced , in a dose dependent manner , cell attachment to fibronectin and collagen coated dishes as well as matrix metalloproteinase 9 secretion . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| Both focal adhesion kinase and c Ras are required for the enhanced matrix metalloproteinase 9 secretion by fibronectin in ovarian cancer cells . ^^^ We have shown previously that treatment of ovarian cancer cells with peritoneal conditioned medium or purified fibronectin ( FN ) activated matrix metalloproteinase 9 secretion and , thereby , cancer cell invasion . ^^^ By use of antisense oligonucleotides to focal adhesion kinase ( FAK ) and a dominant negative mutant of ras ( S17Nras ) , we found that both FAK and c Ras were required for the activation of matrix metalloproteinase 9 secretion by FN . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| Fibronectin bound TNF alpha stimulates monocyte matrix metalloproteinase 9 expression and regulates chemotaxis . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| Thus increased expression of alpha 5 beta 6 results in a fibronectin dependent increase in pro matrix metalloproteinase 9 , matrix metalloproteinase 9 activity increases normal human oral keratinocyte migration , and this may be further dependent on plasmin activation . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| Fibronectin activates matrix metalloproteinase 9 secretion via the MEK 1 MAPK and the PI3K Akt pathways in ovarian cancer cells . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| Free and immobilized vitronectin and fibronectin stimulated the proliferation of cells under serum free conditions and the production and release of urokinase type plasminogen activator , and increased the release of the activated forms of matrix metalloproteinase 2 and matrix metalloproteinase 9 in an alpha ( 5 ) beta ( 3 ) integrin dependent manner . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| OBJECTIVE : This work was conducted to investigate the expression of matrix metalloproteinase 9 ( MMP 9 ) gene in cancer cells by fibronectin adhesion and the underlying mechanism of cell invasion . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| The genes studied included collagen Type 1 ( Col 1 ) , collagen Type 2 ( Col 2 ) , decorin , fibronectin ( FN ) , interleukin 1a ( IL 1alpha ) , bone morphogenetic protein 2 ( BMP 2 ) , Fas , matrix metalloproteinase 1 ( MMP 1 ) , matrix metalloproteinase 9 ( MMP 9 ) , matrix metalloproteinase 13 ( MMP 13 ) , and tumor necrosis factor ( TNF ) . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| TNF alpha did not modify the secretion of matrix metalloproteinase 9 and oncofetal fibronectin . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| IGFBP 1 deficient livers had enhanced signaling via the integrin receptor at early times ( 0 . 5 to 1 hour ) after Fas agonist treatment accompanied by elevated activated matrix metalloproteinase 9 ( MMP 9 ) , a known target of fibronectin signaling and activator of TGF beta . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| BAL fluid was analyzed for cell count and differential , distribution of lymphocytes , and concentration of soluble factors ( histamine , IL 5 , matrix metalloproteinase 9 , tissue inhibitor of metalloproteinase 1 , and fibronectin ) . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| Elevated expression of matrix metalloproteinase 9 , and fibronectin concentration in recurrent epithelial ovarian cancer ] . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| METHODS : In a multicenter prospective study , we determined concentrations of interleukin 6 ( IL 6 ) , tumor necrosis factor alpha ( TNF alpha ) , matrix metalloproteinase 9 ( MMP 9 ) , and cellular fibronectin ( c Fn ) in blood samples obtained on admission from 183 patients with primary hemispheric ICH of < 12 hours ' duration . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| In addition , TNF alpha induced metastatic properties including adhesion to fibronectin , mRNA expression of integrin alpha 5 , production of matrix metalloproteinase 9 and invasion were inhibited by gefitinib without affecting cell proliferation . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| Abnormal expression of matrix components [ collagen 4 , fibronectin , matrix metalloproteinase 9 ( MMP 9 ) and MMP tissue inhibitor 1 ( TIMP 1 ) ] was also significantly reversed by iptakalim . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| Precoating of polycarbonate membranes with matrix components showed that fibronectin and an engineered poly RGD molecule substrate were required for KGF plus heparin to increase MMP 9 activity . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| These results strongly suggest that the invasiveness of squamous cell carcinoma is well correlated with cell matrix adhesion by fibronectin and with focal elaboration of metalloproteinases , especially MMP 9 , which play a major role in degrading the extracellular matrix components . . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| Moreover , degradation of fibronectin and processing of matrix metalloproteinase MMP 9 occurred under these conditions . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| Fraction ( > 100kD ) of conditioned medium of peritoneum could increase remarkably in MMP 9 , and this increase could be inhibited by anti alpha 5 antibody , which is the most popular receptor of fibronectin . ^^^ Furthermore , the addition of fibronectin to SAOV cells induced increase in the secretion of MMP 9 . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| Collagen 4 , fibronectin , and tenascin stimulated macrophages ' MMP 9 expression . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| In an effort to identify this MMP 9 stimulating factor , we examined the effects of extracellular matrix components , such as type 4 collagen , laminin , and fibronectin , on ovarian cancer cells . ^^^ We found that fibronectin increased the MMP 9 activity of NOM 1 cell CM in a concentration dependent manner and that the peritoneal CM contained high level of fibronectin . ^^^ Fibronectin and the peritoneal CM also increased MMP 9 activity and expression in NOM 1 cell lysate , and these effects were blocked by anti integrin alpha5 / FnR antibody . ^^^ These results suggested that fibronectin secreted from peritoneum increased MMP 9 activity and expression , and , in turn , invasiveness of ovarian cancer cells . . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| Fibronectin mediated cell adhesion is required for induction of 92 kDa type 4 collagenase / gelatinase ( MMP 9 ) gene expression during macrophage differentiation . ^^^ Induction of cell adhesion and MMP 9 gene expression in HL 60 cells and blood monocytes was strongly inhibited by neutralizing monoclonal antibodies to fibronectin ( FN ) and its receptor alpha 5 beta1 integrin . ^^^ HL 525 cells , which constitutively display high levels of surface alpha 5 beta1 integrin , adhered and spread on immobilized FN with concomitant induction of MMP 9 gene expression . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| Since fibronectin ( FN ) mediated cell adhesion and spreading are prerequisite for both macrophage differentiation and MMP 9 gene expression in HL 60 cells , we hypothesized that TNF alpha might be involved in modulating the expression of either the FN or its integrin receptor genes . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| MMP 2 ( 72 kDa ) and MMP 9 ( 92 , 130 , and 225 kDa ) were selected since both contain a fibronectin like region and fibronectin binds fibrin . ^^^ Fibronectin and TIMP 1 competition studies indicated that the fibronectin and C terminal MMP 9 domains , respectively , were not involved with fibrin binding . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| Competition based reverse transcription polymerase chain reaction revealed that nondiabetic and diabetic HRECs expressed constitutively mRNA for MMP 2 , MMP 9 , tissue inhibitor of metalloproteinase ( TIMP ) 1 , TIMP 2 , and fibronectin . ^^^ After exposure to 5 or 30 mmol / l glucose , no changes were detected in mRNA levels in MMP 2 or MMP 9 , their inhibitors TIMP 1 and TIMP 2 , or fibronectin in either nondiabetic or diabetic HREC cultures . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| Immunohistochemistry using anti human ( MMP 1 , MMP 2 , MMP 9 , and fibronectin ) antibodies was performed on additional biopsies . ^^^ In ischemic / reperfused myocardium from live pigs investigated , myocyte necrosis could be confirmed by fibronectin immunoreaction in myocytes and MMP 1 and MMP 9 immunoreactions were increased . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| It was found that in the presence of the 70 kDa fibronectin fragment and gelatin , matrix metalloprotease 2 ( MMP 2 ) and matrix metalloprotease 9 ( MMP 9 ) activity in the cell layers was significantly decreased or undetectable , respectively . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| Type 1 and 4 collagens and gelatin but no other purified extracellular matrix nor basement membrane proteins ( types 1 and 4 collagen , laminin 1 and 5 , fibronectin ) were able to bind MMP 9 from the conditioned medium . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| These three neuropeptides had no effect on either adhesion to fibronectin and laminin or on the gelatinolytic activities of MMP 9 in gelatin zymography , nor did they affect the growth of tumor cells at concentrations used in this study . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| RESULTS : MMPs were divided into three main groups : interstitial collagenase ( MMP 1 ) which degrade type 1 and 3 native collagen ; gelatinases ( MMP 9 , MMP 2 ) which act on elastin and type 4 collagen ; stromelysins ( MMP 3 ) with specific proteolytic action towards proteoglycans , fibronectin and laminine . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| To determine the ability of radiation to modulate mesangial cell expression of various molecules involved in promoting extracellular matrix ( ECM ) accumulation [ fibronectin , plasminogen activator inhibitor 1 ( Pai 1 ) , and tissue inhibitor of metalloproteinase 2 ( Timp 2 ) ] and degradation ( Tgfb , plasminogen activators u PA or t PA , matrix metalloproteinases Mmp 2 and Mmp 9 ) , primary cultures of rat mesangial cells ( passage number 6 11 ) were placed in serum free medium 24 h prior to irradiation with single doses of 0 . 5 20 Gy ( 137 ) Cs gamma rays . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| Significant increases in mRNA for fibronectin ( 7 . 5 fold , P < 0 . 01 ) , heparan sulfate proteoglycan core protein ( 53 fold , P < 0 . 001 ) , laminin beta 1 ( 12 fold , P < 0 . 001 ) , collagen alpha 1 ( 4 ) ( 17 fold , P < 0 . 001 ) , collagen alpha 1 ( 3 ) ( fourfold , P < 0 . 001 ) , and MMP 9 ( twofold , P < 0 . 05 ) were observed after perfusion with TGF beta 1 . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| MMP 2 and MMP 9 bioactivity ( zymography ) and immunoactivity were measured in the culture supernatants together with total human chorionic gonadotrophin ( HCG ) , fetal fibronectin ( FFN ) and leptin . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| The effects of vinblastine ( VBL ) on endothelial cell functions involved in angiogenesis , namely proliferation , chemotaxis , spreading on fibronectin ( FN ) , secretion of matrix metalloproteinase 2 ( MMP 2 ) and MMP 9 , and morphogenesis on Matrigel were tested in vitro , whereas its effects on angiogenesis were studied in vivo by using the chick embryo chorioallantoic membrane ( CAM ) model . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| In tumor tissue specimens of 27 primary and 17 secondary glioblastomas and the precursor lesions , the immunohistochemical expression patterns of the membrane protein CD44s , the basal lamina proteins laminin , collagen 4 , and fibronectin , the lectin galectin 3 recognizing tenascin and N CAM as well as of the matrix degrading enzymes matrix metalloproteinase MMP 2 and MMP 9 , and cathepsin D were studied . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| PURPOSE : To determine the ability of radiation to modulate kidney tubule epithelial cell expression of various molecules involved in regulating extracellular matrix accumulation ( collagen types 1 and 3 , fibronectin , plasminogen activator inhibitor 1 ( PAI 1 ) , TGF beta and tissue inhibitor of metalloproteinases 2 ( TIMP 2 ) ) and degradation ( plasminogen activators u PA or t PA , MMP 2 and MMP 9 ) . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| We demonstrated that the transcriptional expression of MT 1 MMP , MMP 9 , cathepsin K , and TRAP in highly enriched osteoclasts were regulated by different matrix proteins that bind to integrin on osteoclast , such as collagen type 1 ( CoI ) , fibronectin ( FN ) , vitronectin ( VN ) , osteopontin ( OPN ) , and ivory . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| Since the invasive ability of the distally located extravillous cytotrophoblast of cell columns is known to be regulated by a variety of proteases and some extracellular matrix molecules , we tested the influence of leptin on the in vitro production of matrix metalloproteinase ( MMP ) 2 , MMP 9 and fetal fibronectin ( fFN ) by cytotrophoblastic cells . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| Forty five gliomas ( astrocytomas , glioblastomas , oligodendrogliomas , and mixed gliomas ) were investigated for the immunohistochemical expression of the membrane protein CD44s , the basal lamina proteins laminin , collagen 4 , and fibronectin , the lectin galectin 3 recognizing tenascin and N CAM , as well as for the matrix degrading enzymes metalloproteinases MMP 2 , MMP 9 , and cathepsin D . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| Fibronectin , however , also induced the secretion of MMP 9 . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| The infiltrating cells did not express fibronectin receptor alpha5beta1 integrin but showed MMP 9 secretion and cell surface associated MMP 2 . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| We found induction of MMP 9 activity and fibronectin degradation . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| RESULTS : Fibronectin ( 5 micrograms / ml ) was found to stimulate the secretion of MMP 2 but not MMP 9 by SKOV 3 cells . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| METHODS : The tissue distribution of MMP 2 , MMP 9 , TIMP 1 , TIMP 2 and fibronectin was analysed by immunohistochemistry . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| We measured expression of the extracellular matrix protein fibronectin , the activity of the gelatinases MMP 2 and MMP 9 , the proinflammatory transcription factor NFkappaB , and the adhesion molecules , vascular cell adhesion molecule ( VCAM ) 1 and platelet endothelial cell adhesion molecule ( PECAM ) 1 in hearts of DOCA salt hypertensive ( DS ) rats treated or not with the endothelin ET ( A ) antagonist BMS 182874 ( BMS ) . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| We report that minocycline , a widely used generic drug with a good safety record , inhibited MMP activity , reduced production of MMP 9 and decreased the transmigration of T lymphocytes across a fibronectin matrix barrier . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| Comparisons were made of intrarenal expression of TGF beta , collagen , fibronectin , metalloproteinase 2 ( MMP 2 ) , MMP 9 , and tissue inhibitor of MMP 2 , using reverse transcriptase polymerase chain reaction . ^^^ RESULTS : Intrarenal expression of TGF beta , collagen , fibronectin , MMP 2 , MMP 9 , and tissue inhibitor of MMP 2 was significantly increased in rats treated with CsA for 180 days compared with untreated rats and those treated for 30 days . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| Pretreatment of cells with genistein significantly decreased the secretion of MMPs , particularly MMP 9 in cells maintained on ECM protein ( FN ) indicating a phosphorylation dependent signalling process in mediating matrix effect . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| DESIGN AND METHODS : The ability of bone marrow plasma cells to adhere to VN and FN and the consequent formation of focal adhesion plaques on the cell surface , their composition and phosphorylation of several signal transduction proteins , cell proliferation and secretion of matrix metalloproteinase 2 ( MMP 2 ) and 9 ( MMP 9 ) and urokinase type plasminogen activator ( uPA ) were studied . ^^^ Free and immobilized VN and FN stimulated cell proliferation and the production and the release of uPA , and increased the release of the activated forms of MMP 2 and MMP 9 in an avb 3 integrin dependent manner . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| Furthermore , activation of MMP 2 and MMP 9 was greatly reduced for HT 1080 fibrosarcoma cells cultured on either of the fibronectin fragments compared to full length FN . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| We used electron microscopy and immunoconfocal ( IF ) labeling for bFGF , matrix metalloproteinase ( MMP ) 2 , MMP 9 , tissue type plasminogen activator ( tPA ) , its inhibitor ( PAI 1 ) , fibronectin ( FN ) , and Ki 67 . ^^^ Quantitative IF showed that adventitial MMP 2 , MMP 9 , and FN were 9 . 2 , 7 . 5 , and 8 . 6 fold , bFGF was 5 . 1 fold , and PAI 1 was 3 . 4 fold higher in CV than in normal vessels ( NV ) . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| The levels of interleukin ( IL ) 1alpha , IL 1beta , IL 6 , IL 8 , matrix metalloproteinase ( MMP ) 1 , MMP 2 , MMP 9 , tissue inhibitors of matrix metalloproteinase ( TIMP ) 1 , TIMP 2 , granulocyte elastase , and fetal fibronectin in cervical diluted specimens were measured by immunoassay , and the uterine cervix was assessed by transvaginal ultrasonography . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| This activation proceeded in a time and dose dependent manner , facilitating the efficient cleavage of fibronectin by MMP 9 . ^^^ Specific anti MMP 26 and anti MMP 9 functional blocking antibodies both reduced the invasiveness of ARCaP cells across fibronectin or type 4 collagen . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| Incubation of monocytes with matrix , fibronectin , laminin and collagen 4 enhanced production of interleukin 1beta ( IL 1beta ) , interleukin 6 ( IL 6 ) , TNF alpha and metalloproteinase 9 ( MMP 9 ) when compared to cells incubated in plastic wells . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| We used enzyme linked immunosorbent assay and reverse transcriptase polymerase chain reaction to assess the production of the following proteins : matrix metalloproteinase ( MMP ) 3 , MMP 9 , tissue inhibitor of MMP 1 , transforming growth factor beta 1 , thrombospondin 1 , tenascin , and fibronectin . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| FN and LN induced MMP 9 to lesser extents compared with TN C . b FGF had no effect on MMP 9 expression . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| Dynamics of MMP 2 and MMP 9 content in wound or burn fluids as well as that of adhesive protein fibronectin content could be used as a base for development of method of controlling the extracellular matrix remodelling process . . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| Immunohistochemistry showed positive staining for MMP 9 , fibronectin , and eosinophil cationic protein ( ECP ) on the superficial corneal stroma of the ulcer bed , but no inflammatory cells . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| Transfection of a double stranded RNA that targets the MMP 9 mRNA into COH cells depleted the corresponding mRNA and protein as demonstrated by reverse transcriptase PCR , enzyme linked immunosorbent assay , and gelatin zymography . proMMP 9 extinction resulted in the following : ( 1 ) decreased spreading on extracellular matrix ( fibronectin , laminin , collagen 4 ) coated surfaces , ( 2 ) inhibition of migration toward fibronectin , and ( 3 ) induced aggregation , which was specifically disrupted by a function blocking E cadherin antibody . ^^^ Finally , an inhibitor of gelatinolytic activity of pro MMP 9 did not reduce COH cell migration confirming that the enzymatic property of COH MMP 9 was not required for migration toward fibronectin . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| METHODS : Using RT PCR , intrarenal expression of TGF beta , collagen , fibronectin , MMP 2 , MMP 9 and TIMP 2 were studied in renal biopsies from patients with histological diagnosis of CsA or Tac nephrotoxicity and acute rejection . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| Col 4 and Fn distribution in prostatic adenocarcinoma and correlation of 67LR , MMP 9 and TIMP 1 expression with Gleason score . ^^^ RESULTS : Overexpression of Col 4 , Fn , 67LR and MMP 9 was detected in PAc as compared with BPH , whereas no difference was determined in TIMP 1 expression . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| We also demonstrate that the deposition of fibronectin and tenascin C matrices by SCC9beta6 cells and peritumor fibroblast cocultures is counter regulated by the UPA > MMP 3 > MMP 9 pathway . ^^^ When the SCC9beta6 / PTF cocultures were incubated with TGFbeta 1 , the deposition of fibronectin and tenascin C as well as the activation of MMP 3 and MMP 9 was increased . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| Addition of the broad spectrum matrix metalloprotease ( MMP ) inhibitor FN 439 , neutralizing MMP 9 or tumour necrosis factor alpha ( TNF alpha ) antibodies reduced invasiveness to basal levels . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| Finally , no difference of metalloprotease ( MMP 2 , MMP 3 , MMP 7 , MMP 9 ) activity was observed between cells plated on FN and on FN plus TN , except for B MM which showed an increased MMP 7 activity when TN was added to FN . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| In vitro effects of flunisolide on MMP 9 , TIMP 1 , fibronectin , TGF beta 1 release and apoptosis in sputum cells freshly isolated from mild to moderate asthmatics . ^^^ We evaluated the ability of flunisolide to inhibit in vitro the release of metalloproteinases 9 ( MMP 9 ) , tissue inhibitor metalloproteinases 1 ( TIMP 1 ) , transforming growth factor ( TGF beta ) and fibronectin by sputum cells ( SC ) as well as to induce sputum eosinophil apoptosis . ^^^ CONCLUSIONS : These results demonstrate that flunisolide may play an important role in the inhibition of airway inflammation and remodelling , by promoting the resolution of eosinophilic inflammation and by inhibiting the release of MMP 9 , TIMP 1 , TGF beta and fibronectin . . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| Two matrix metalloproteinases , MMP 2 and MMP 9 , contain each three fibronectin type 2 like modules , which form their collagen binding domains ( CBDs ) . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| LN and FN could stimulate the secretion of MMPs by MHCC 97 H cells cultured in vitro , especially MMP 9 and its activated type . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| More interestingly , however , MMP 9 expression and fibronectin concentration were significantly elevated and the activated forms of both MMP 9 and MMP 2 were more frequent in ovarian cancer patients who developed recurrent disease . ^^^ Our data support the notion that high expression of MMP 9 and fibronectin indicates poor prognosis of ovarian cancer patients . . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| Exposure of CF to pioglitazone caused an antiproliferative ( P < 0 . 0001 ) and hypertrophic ( P < 0 . 0001 ) effect ; reduced type 4 collagen secretion ( P < 0 . 01 ) , fibronectin secretion ( P < 0 . 0001 ) , and proline incorporation ( P < 0 . 0001 ) ; decreased MMP 9 activity ( P < 0 . 05 ) ; and reduced tissue inhibitor of metalloproteinase 1 ( TIMP 1 ) and TIMP 2 secretion ( P < 0 . 001 and P < 0 . 0001 , respectively ) . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| RESULTS : The results showed that rhein markedly inhibit the proliferation of HMCs , significantly reduce the bioactivity of TGFbeta 1 and FN secretion in HMCs , and decrease the increased activity of p38MAPK , but showed no action on the activities of MMP 2 and MMP 9 . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| RESULTS : Various amounts of matrix metalloproteinase 2 ( MMP 2 ) , 9 ( MMP 9 ) , fibronectin ( FN ) , and their fragments were identified on 2 D PAGE gels from cancer bearing patients , but not from normal individuals . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| The MMPs ( matrix metalloproteinases ) MMP 9 and 2 each possess a unique CBD ( collagen binding domain ) containing three fibronectin type 2 like modules . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| RESULTS : The levels of MMP 9 and fibronectin , but not those of MMP 2 , were significantly higher in tumour tissues and in the ascites fluid of the recurrent patient group and the patient group who did not survive , as compared to the non reccurent cases . ^^^ CONCLUSION : Our data support that high expression of MMP 9 and fibronectin indicate poor prognosis for ovarian cancer patients who have similar clinicopathological prognostic factors . . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| Incubation of cultured human coronary smooth muscle cells with human HGF ( 1 100 ng / ml ) did not significantly alter cell migration and collagen 1 , fibronectin , EMMPRIN , MMP 1 , MMP 2 and MMP 9 release . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| We measured VEGF A , PlGF , SCF , MMP 9 , EDB+ fibronectin , sVEGFR 2 , sVEGFR 1 , salphaVbeta 3 , sTie 2 , IL 8 and CRP in the blood of 22 healthy volunteers , 17 early breast , 17 early colorectal , and 8 advanced sarcoma / melanoma cancer patients . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| Membrane bound MMP ( MT 1 MMP ) , MMP 9 , and fibronectin levels were also increased , and ABT 627 treatment did not have an effect on MMP activity and expression . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| The migratory response of mesenchymal cells cultured in 3D fibrin matrices supplemented with fibronectin was associated with specific activated MMP 9 . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| The localization and expression of tTG , MMP 9 gelatinase , and the ECM component fibronectin ( FN ) in kidneys was determined by immunohistochemistry and measured by semi quantitative analysis . ^^^ Enhanced cross linking of ECM by tissue transglutaminase and decreased degradation due to reduced active MMP 9 expression may be at least partially responsible for the deposition of FN within injured glomeruli in experimental FSGS . . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| Western blotting was used to analyse the expression of cartilage specific markers , such as collagen type 2 and cartilage specific proteoglycan , fibronectin , cell adhesion and signal transduction receptor beta 1 integrin , matrix metalloproteinases ( MMP 9 , MMP 13 ) , cyclo oxygenase ( COX ) 2 and the apoptosis commitment marker , activated caspase 3 . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| Gene expression profile of MMP 2 , MMP 9 , MT 1 MMP , fibronectin , procollagen type 1 , c fos and c jun , were determined by quantitative real time ( qRT ) PCR . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| Among matrix metalloproteinases ( MMPs ) , the subfamily of gelatinases ( MMP 2 , MMP 9 ) is of particular interest due to their ability to degrade type 4 collagen and other non fibrillar collagen domains and proteins such as fibronectin and laminin . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| The in vivo transfection of the ets 1 gene into nephritic kidney resulted in the increases in glomerular MMP 1 , MMP 3 , and MMP 9 mRNA , decreases in mesangial ECM deposition , and attenuation of fibronectin extradomain A ( EDA ) and type 1 collagen expression . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| Expression of matrix metalloproteinases ( MMP 2 , MMP 3 , and MMP 9 ) and fibronectin in lichen planus . ^^^ Immunochemical stainings were performed for MMP 2 , MMP 3 , MMP 9 and fibronectin . ^^^ OBJECTIVE : To determine MMP 2 , MMP 3 , MMP 9 and FN expressions in LP and discuss the possible associations . ^^^ |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14780 and P02751 |
Pubmed |
SVM Score :0.0 |
| NA |
|