Interacting proteins: O75173 and P02751 |
Pubmed |
SVM Score :0.57519883 |
Interaction between ADAMTS 4 and fibronectin was demonstrated by chemical cross linking . 0.57519883^^^ Wild type ADAMTS 4 was co localized with fibronectin as determined by confocal microscopy on the cell surface of stable 293T transfectants expressing ADAMTS 4 , although ADAMTS 4 deletion mutants , including Delta Sp ( Delta Arg ( 693 ) Lys ( 837 ) , lacking the spacer domain ) , showed negligible localization . 0.57516262^^^ |
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Interacting proteins: O75173 and P02751 |
Pubmed |
SVM Score :0.0 |
Neither ADAM TS 5 nor ADAM TS 4 was able to cleave the extracellular matrix proteins fibronectin , thrombospondin , type 1 collagen , type 2 collagen , gelatin or general protein substrates such as casein and transferrin . ^^^ |
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Interacting proteins: O75173 and P02751 |
Pubmed |
SVM Score :0.0 |
Linkage analysis of the genes involved in EDS and other connective tissue disorders , excluded COL1A1 , COL1A2 , COL2A1 , COL3A1 , COL5A1 , COL5A2 , COL5A3 , COL6A1 , COL6A2 , ADAMTS 2 , ELN , FN 1 , TNXA , and TNXB as candidate genes in the family under study , thus indicating that ATS is a distinct clinical and molecular entity . . ^^^ |
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