| Interacting proteins: P02746 and P02745 |
Pubmed |
SVM Score :0.0 |
| Northern blot and dot blot analysis showed that the mRNAs for all classical pathway complement components ( C1qA chain , C1qB chain , C1qC chain , C1r , C1s , C 4 and C 2 ) and the fluid phase regulatory components ( C 1 inhibitor , C 4 bp and factor 1 ) were present in all three types of synovial membrane . ^^^ In three instances mRNA was detected in the absence of secreted protein : mRNAs for the C1qA and C1qC chains were detected in HUVEC , whereas the mRNA for the C1qB chain was not , and C 4 mRNA was detected in both fibroblasts and HUVEC . ( ABSTRACT TRUNCATED AT 250 WORDS ) . ^^^ |
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| Interacting proteins: P02746 and P02745 |
Pubmed |
SVM Score :0.0 |
| The three genes C1qA , C1qB , and C1qC are closely arranged on a 19 kilobase stretch of DNA in the 5 ' to 3 ' orientation A C B . ^^^ Southern blot analysis of chromosomal DNA from 14 vertebrate species demonstrated highest similarity between the C1qB genes , followed by C1qC and finally C1qA . . ^^^ |
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| Interacting proteins: P02746 and P02745 |
Pubmed |
SVM Score :0.0 |
| C1q genes are composed of three genes , C1qa , C1qc , and C1qb , arranged in this order , and each gene consists of two exons separated by one intron . ^^^ |
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| Interacting proteins: P02746 and P02745 |
Pubmed |
SVM Score :0.0 |
| Here we show that components of both the classical ( C1qa , C1qb , C1qc , C 2 and C 4 ) and alternative ( C 3 , B and adipsin ) pathways are expressed by uninjured peripheral nerve as well . mRNAs of components of the alternative pathway were predominantly found in the peri / epineurium , although factor C 3 and factor B were also detected in the endoneurial compartment of adult nerve . ^^^ |
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