| Interacting proteins: P02533 and P00533 |
Pubmed |
SVM Score :0.0 |
| RESULTS : Thirteen cases ( eight DCIS and five IDC ) showed expression of CK 8 , CK 14 , CK 18 , vimentin , and EGFR , consistent with a stem cell phenotype , whereas 44 cases ( 27 DCIS and 17 IDC ) showed expression of CK 8 and CK 1 , weak or negative expression of CK 18 , but were negative for vimentin and EGFR , consistent with a luminal cell phenotype . ^^^ |
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| Interacting proteins: P02533 and P00533 |
Pubmed |
SVM Score :0.0 |
| EXPERIMENTAL DESIGN : Histopathologic material from 182 tumors in BRCA 1 mutation carriers , 63 BRCA 2 carriers , and 109 controls , collected as part of the international Breast Cancer Linkage Consortium were immunohistochemically stained for CK 14 , CK5 / 6 , CK 17 , epidermal growth factor receptor ( EGFR ) , and osteonectin . ^^^ RESULTS : All five basal markers were commoner in BRCA 1 tumors than in control tumors ( CK 14 : 61 % versus 12 % ; CK5 / 6 : 58 % versus 7 % ; CK 17 : 53 % versus 10 % ; osteonectin : 43 % versus 19 % ; EGFR : 67 % versus 21 % ; P < 0 . 0001 in each case ) . ^^^ |
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| Interacting proteins: P02533 and P00533 |
Pubmed |
SVM Score :0.0 |
| Our immunohistochemical antibody panel included pan cytokeratin ( CK ) , basal cell type CKs ( 34betaE12 , CK5 / 6 , CK 14 , CK 17 ) and vimentin antibodies , antibodies to established ( SMA , CD 10 , p 63 , S 100 , maspin , calponin , GFAP , SM myosin ) , and novel ( CD 29 , 14 3 3sigma ) myoepithelial markers , as well as antibodies to CD 34 , desmin , h caldesmon , steroid receptors ( estrogen , progesterone , androgen ) , and EGFR ( Her 1 ) . ^^^ |
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| Interacting proteins: P02533 and P00533 |
Pubmed |
SVM Score :0.0 |
| The high rate of cell proliferation was accompanied by overexpression of cell cycle progression and tumorigenesis biomarkers , including proliferating cell nuclear antigen , cyclin D 1 , cyclin dependent kinase 4 , p 53 , cytokeratin 14 , epidermal growth factor receptor , and by a reduced rate of apoptosis . ^^^ |
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| Interacting proteins: P02533 and P00533 |
Pubmed |
SVM Score :0.0 |
| To characterize the epidermal compartment keratin 14 , keratin 16 , epidermal growth factor receptor , apoptotic and Ki 67 positive cells were examined . ^^^ |
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| Interacting proteins: P02533 and P00533 |
Pubmed |
SVM Score :0.0 |
| NIKS cells express steady state levels of transforming growth factor alpha , transforming growth factor beta 1 , epidermal growth factor receptor , c myc , and keratin 14 mRNAs comparable with the parental BC 1 Ep keratinocyte strain . ^^^ |
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| Interacting proteins: P02533 and P00533 |
Pubmed |
SVM Score :0.0 |
| Using a panel of antibodies to ER alpha , PR , HER 2 / neu , and EGFR , along with cytokeratin ( CK ) markers ( CK5 / 6 , CK 8 , CK 14 , CK 17 , and CK 18 ) , we found that all 3 cell origin subtypes can express ER alpha and PR , and their expression is higher in non high grade DCIS than in high grade DCIS ; the expression of HER 2 / neu is associated with luminal subtype only in non high grade DCIS , but can be seen in all 3 subtypes in high grade DCIS ; the expression of EGFR is low and is present only in luminal cell subtypes in both high and non high grade DCIS . ^^^ |
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| Interacting proteins: P02533 and P00533 |
Pubmed |
SVM Score :0.0 |
| Immunohistochemistry with antibodies for HER 2 , ER , EGFR , CK5 / 6 , CK 14 and p 63 was performed according to standard methods . ^^^ |
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| Interacting proteins: P02533 and P00533 |
Pubmed |
SVM Score :0.0 |
| In this study , we used tissue microarray to examine the expression of basal cytokeratins ( CK ) ( CK 5 and CK 14 ) and luminal CK ( CK8 / 18 ) , epidermal growth factor receptor , c kit , hormone receptors ( HRs ) , p 53 , and Her2 / neu in 776 consecutive patients diagnosed with invasive breast carcinoma from January 1993 to December 1998 and categorized these cases into 5 subgroups ( basal like , HR expressing , Her2 / neu overexpressing , HR and Her2 / neu expressing , and null subtypes negative for all markers ) , based on the immunohistochemical data . ^^^ |
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| Interacting proteins: P02533 and P00533 |
Pubmed |
SVM Score :0.0 |
| Ultraviolet B irradiation increases keratin 5 and keratin 14 expression through epidermal growth factor receptor of SV 40 transformed human keratinocytes . ^^^ |
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| Interacting proteins: P02533 and P00533 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P02533 and P00533 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P02533 and P00533 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P02533 and P00533 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P02533 and P00533 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P02533 and P00533 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P02533 and P00533 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P02533 and P00533 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P02533 and P00533 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P02533 and P00533 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P02533 and P00533 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P02533 and P00533 |
Pubmed |
SVM Score :0.0 |
| NA |
|