| Interacting proteins: P45452 and P02458 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P45452 and P02458 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P45452 and P02458 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P45452 and P02458 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P45452 and P02458 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P45452 and P02458 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P45452 and P02458 |
Pubmed |
SVM Score :0.0 |
| Subsequently , collagenase 3 ( matrix metalloproteinase 13 ; MMP 13 ) is up regulated as type 10 collagen is expressed leading to extensive cleavage and removal of type 2 collagen and of the remaining COL 2 domain of type 9 collagen alpha 1 ( 9 ) chain . ^^^ |
|
| Interacting proteins: P45452 and P02458 |
Pubmed |
SVM Score :0.0 |
| For gene analysis , conventional and quantitative polymerase chain reactions were used for COL1A2 , COL2A1 , aggrecan , BMP 2 , biglycan , decorin , osteonectin , fibromodulin , fibronectin , matrix metalloproteinase 13 ( MMP 13 ) , and tissue inhibitor of MMP 1 . ^^^ |
|
| Interacting proteins: P45452 and P02458 |
Pubmed |
SVM Score :0.0 |
| Left ventricular ( LV ) mRNA [ MMP 1 , 2 , 3 , 7 , 9 , 11 , 13 , 14 ; TIMP 1 , 2 , 3 , 4 ; and collagen alpha 1 ( 1 ) and alpha 1 ( 3 ) ] and protein ( MMP 2 and MMP 9 zymographic activity ; Western blot analysis of MMP 13 , and TIMP 1 , 2 , 4 ) levels could be quantified . ^^^ |
|
| Interacting proteins: P45452 and P02458 |
Pubmed |
SVM Score :0.0 |
| Specifically , we studied the expression of genes encoding COL2A1 and COL10A1 , the latter a marker of cellular hypertrophy , the matrix metalloproteinases ( MMP ) , MMP 13 and MMP 9 , as well as the transcriptional factors , Sox 9 and Cbfa 1 , the growth factors basic fibroblast growth factor ( bFGF ) , parathyroid hormone related peptide ( PTHrP ) , transforming growth factor ( TGF ) beta 1 , and beta 2 , Indian hedgehog ( Ihh ) , and the matrix protein osteocalcin . ^^^ The upregulation of expression of COL2A1 , its transcriptional activator Sox 9 , osteocalcin , MMP 13 , and TGFbeta 2 was observed immediately before and at the onset of cyclin B 2 expression and also in the hypertrophic zones . ^^^ |
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