Pubmed abstracts for Protein-Protein Interaction search result :

Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The HT 1 cells expressed CD 1 , CD 2 , CD 3 , CD 4 , CD 5 , CD 7 , CD 8 , CD 57 , and terminal deoxynucleotidyl transferase ( TdT ) but lacked B cell associated antigens and myeloid associated antigens . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
In none of these patients did the leukemic cells react with CD 1 , CD 2 , CD 3 , CD 4 , CD 5 , CD 8 , CD 10 , CD 19 or CD 20 . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Negative reactions were also seen with CD 4 , CD 8 , CD 5 , CD 7 , CD 16 , CD 30 and CD 57 . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
However , although they do not express the T cell markers Thy 1 , CD 2 , CD 3 , CD 4 and CD 5 , 20 % 30 % of dendritic cells are positive for the interleukin 2 receptor alpha chain ( CD 25 ) , and about 30 % express intermediate levels of CD 8 . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The proportion of nucleated splenocytes bearing B lymphocyte markers B 220 , surface IgM ( sIgM ) and sIgD , as well as the T lymphocyte markers Thy 1 . 2 , CD 5 , CD8a and CD 4 were quantitated by flow cytometric analysis ( FACS ) throughout postpartum development in the A / J mouse . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
These cells are Thy 1+ , CD45+ , CD3+ and asialo GM1+ but CD 5 , CD 4 , CD 8 , or Ia 1 , and express T cell receptor ( TCR ) gamma delta . ^^^ Using 1F4 and a recently developed monoclonal antibody to rat TCR alpha beta , we could identify dendritic CD 4 , CD 8 , CD 5 , CD3+ , TCR alpha beta cells in the rat epidermis . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
After transfection , the parental D 011107 T cell line reexpressed CD 5 and CD 4 surface molecules . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The percentages of total B lymphocytes ( CD 19 ) , natural killer ( NK ) cells ( CD 16 ) , T lymphocytes and their subsets ( CD 2 , CD 3 , CD 4 , CD 5 , CD 7 , CD 8 ) , and IL 2R ( CD 25 ) were found to be within the range found in normal donors . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Molecular associations between the T lymphocyte antigen receptor complex and the surface antigens CD 2 , CD 4 , or CD 8 and CD 5 . ^^^ This provided a sensitive assay for molecular complexes , and associations were demonstrated between the TCR complex and the surface antigens CD 2 , CD 4 , or CD 8 and CD 5 in normal rat T cells . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Expression of thymocyte differentiation markers ( Thy 1 , CD 5 , CD 8 , CD 4 , CD 3 , and HSA ) is severely affected in Ts 16 fetuses aged 14 18 gestational days . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Unlike the sIg CD 5 transplantable RCS 10 cell line , the IgM+ CD5+ NJ 101 lymphoma cells will grow in immuno compromised hosts , such as irradiated recipients or in recipients treated with CD 4 mAb in vivo . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
We examined the TcR gamma delta usage and co expression of CD 5 , CD 4 , CD 8 and major histocompatibility complex ( MHC ) class 2 on isolated sheep IEL and lamina propria lymphocytes ( LPL ) , and compared them with the TcR gamma delta + cells in peripheral blood , intestinal lymph and jejunal Peyer ' s patches ( PP ) . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Anti CD 4 coprecipitated p56lck , p 32 , and CD3 / TCR zeta subunits but precipitated less CD 5 , suggesting the existence of CD 4 TCR zeta / CD3 complexes distinct from the CD 5 TCR zeta / CD3 complexes . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Immunohistochemical analysis of six cases showed no reactivity with CD 1 , CD 2 , CD 4 , CD 5 , CD 8 , and CD 10 and high reactivity with CD 19 and CD 20 . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The number of neurons in the sympathetic ganglia was counted and four subpopulations of mononuclear inflammatory cells were identified by monoclonal antibodies MHC 2 , CD 8 T cells / NK cells , CD 5 T cells , CD 4 T cells / macrophages . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Useful methods for characterizing AIDS related non hodgkin ' s lymphomas include immunophenotypic studies using B cell differentiation and activation antigens ( HLA DR , CD 10 , CD 19 , CD 20 , CD 21 , CD 22 , CD 23 , CD 38 ) , evaluation of expression of surface immunoglobulins ( IgS ) , activation and proliferation ( CD 25 , CD 30 , CD 71 , Ki 67 ) , and identification of T cell markers ( CD 1 , CD 2 , CD 3 , CD 4 , CD 5 , CD 7 , CD 8 ) . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Leukocyte antigens investigated were CD 2 , CD 3 , CD 4 ( two antibodies ) , CD 5 , CD 8 , CD 25 , CD 30 , CD 63 antigens and HLA DR ; HIV 1 encoded antigens were gag p 24 , pol reverse transcriptase , and env gp 41 and gp 120 . ^^^ Compared with uninfected cells , a significantly lower density was found on infected cells in labelling for CD 4 , CD 5 and anti HLA DR . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
CD 5 , CD 15 and CD 45 antigens were detected at 6 weeks of gestation , whereas CD 4 , CD 8 , CD 10 , CD11c , CD 14 and IgM were not expressed at this stage . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
TcR gamma delta + IEL , although a minority population , are also phenotypically distinct , insofar as they are 50 % CD8+ , mainly 5 delta 1+ 5 gamma 9 and CD 4 CD 5 . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The immunological behaviour of the host was assessed through the determination of lymphoid populations ( CD 2 , CD 4 , CD 5 and CD 8 ) and cytolytic cells were studied with monoclonal antibodies CD and CD 16 . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
With a combination of 15 antibodies , including CD 2 , CD 3 , CD 4 , CD 5 , CD 7 , and CD 8 for T cell marker analysis , CD 10 , CD 19 , CD 20 , surface immunoglobulins , and cytoplasmic mu chain for B cell marker analysis , CD 13 and CD 33 for myeloid marker analysis , and HLA DR and CD 25 for other marker analysis , acute lymphoblastic leukemias of T cell type , cALL type , pre B cell type and B cell type , acute myeloid leukemias , acute unclassified leukemias and adult T cell leukemias could be clearly diagnosed by immunophenotyping of cell membrane molecules . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Among the monoclonal antibodies ( mAb ) defining the B cell clone phenotype or activation state ( CD 19 , CD 20 , CD 21 , CD 22 , CD 23 , CD 24 , CD 5 , CD 10 , CD11a , and Ki 67 ) , only CD 23 ( P = . 0003 ) and Ki 67 ( P = . 0007 ) revealed statistical association with the percentage of naive CD 4 lymphocytes . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Surface markers of the leukemic cells were CD 2 ( + ) , CD 3 ( + ) , CD 5 ( + ) , CD 7 ( + ) , CD 8 ( + ) , and CD 4 ( ) . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Consecutive sections were stained for T 1 ( CD 5 ) , T 4 ( CD 4 ) , T 8 ( CD 8 ) , TAC ( CD 25 ) , the delta chain markers delta TCR 1 and delta TCS 1 , and the beta chain marker beta F 1 . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
All these Ts cell clones were shown to be Thy1 . 2+ , CD 4 , CD 5 , CD8+ , and to express CD 3 and the alpha beta heterodimer of the T cell receptor . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Here we document that T 560 cells are IgG2a kappa + , Ia+ , B220+ , J11d . 2+ , CD 3 , CD 4 , CD 5 , Mac 1 , Mac 2 , non specific esterase . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
PI sheep had an increased percentage of cells expressing the T cell associated molecules CD 5 , CD 4 , CD 8 and T 19 , also an increase in cells expressing CD 1 and a population of cells expressing low levels of the T 19 molecule which was not present in control sheep . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The level of cells defined by monoclonal antibodies ( CD 1 , CD 2 , CD 3 , CD 4 , WT 31 , and CD 5 ) was less than 3 % . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Thy 1 ( CD 5 ) , L3 / T4 ( CD 4 ) and Lyt 2 ( CD 8 ) positive cells were located predominantly at the basal area adjacent to fat cells under the lymphoid tissue . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Of special interest was the unexpectedly high proportion of cells expressing T cell markers ( CD 3 , CD 5 , CD 4 greater than CD 8 ) in the amyloid nodules of both patients . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The number of CD 5 , CD 4 , CD 8 , natural killer cells and the CD 4 / CD 8 ratio were significantly decreased . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Lack of antigens reactive with CD 2 , CD 3 , CD 5 , and WT 31 monoclonal antibody panels was one factor in bad prognosis , but the presence of CD 4 and CD 8 antigen abnormalities was much more significant . . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Myelomonocytic cells in peripheral blood expressed both myeloid antigens ( CD11b , CD 13 , CD 14 , CD 15 , CD 33 ) and T / B lymphoid antigens ( CD 2 , CD 4 , CD 5 , CD 7 , CD 10 , PCA 1 ) . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
T 560 is IgG2a kappa + , Ia+ , B220+ , J11d+ , Thy 1 , CD 3 , CD 4 , CD 5 , Mac 1 , Mac 2 , nonspecific esterase negative and binds bromelain treated mouse RBC but not SRBC or ORBC . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
To investigate whether the retargeting of resting CTL can benefit from cooperative signaling between the TCR / CD3 complex and various accessory molecules , such as CD 2 , CD 4 , CD 5 , and CD 8 , we have constructed a series of trispecific F ( ab ' ) 3 derivatives . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Our results indicated that among B cells , CD 5 cells predominated ( about 92 % ) , the minor CD5+ fraction showed variations between individuals but sometimes was as high as 20 % in B cells ; the CD45RA+CD29 subset ( naive cells ) accounted for 31 . 56 + / 10 . 03 % in CD 4 cells , as compared to CD4+CD29+CD45RA ( memory cells ) ( 46 . 54 + / 10 . 35 % ) , while CD4+CD29+CD45RA+ ( transition cells between naive and memory state ) represented 9 . 6 + / 5 . 3 % as compared to double negatives ( 12 . 3 + / 5 . 24 % ) . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Three years following the accident , exposed subjects were compared to residents of a nearby unexposed community for the following immunological parameters : white blood cell count , total lymphocyte count , percent and total lymphocyte subsets ( CD 5 , CD 4 , CD 8 , CD 19 , CD 25 , and CD 26 cells ) , prevalence of autoantibodies , and antibodies to HCHO human serum albumin ( HCHO HSA ) conjugate . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Factors examined included white blood cell ( WBC ) level , age , gender , race ( black 5 other ) , presence of a mediastinal mass , hepatomegaly , splenomegaly , marked lymphadenopathy , hemoglobin level , platelet count , blast cell expression of antigens such as the common acute lymphoblastic leukemia antigen ( CALLA , CD 10 ) , HLA DR , and T cell associated antigens ( CD 3 , CD 4 , CD 8 , CD 7 , CD 5 , and THY ) . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Nonpulsed macrophages were lysed to a much lower but still significant extent . hsp 65 induced effector cells expressed CD 3 , CD 5 , CD 4 , CD 8 and CD 56 markers . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Flow cytometry of isolated IEL stained with monoclonal antibodies against Thy 1 , CD 3 , CD 4 , CD 5 and CD 8 showed that scid / scid mice IEL contained cells with the Thy 1 CD 4 CD5 CD8+ phenotype . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The effects of selectively depleting for pan T ( Thy 1+ ) , CD 4 ( L3T4+ ) , CD 8 ( Lyt 2+ ) , or CD 5 ( Lyt 1+ ) cells were then evaluated and the results were compared with the incidence and severity of GVHD in the recipients . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The mAb used in the panel were : CD 1 , ( T 6 ) , CD 2 ( T 11 , X 11 , D 66 , clone 2 ) , CD 3 ( T3 / Leu4 ) , CD 4 , ( T4 / Leu3a ) , CD 5 ( Leu 1 , T 1 , A 50 , I73D9 ) , CD 7 ( Leu 9 , I 21 ) , CD 8 ( T8 / Leu2a ) and HNK 1 . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Intrathymic changes in murine CD 3 , CD 5 and CD 8 expression after in vivo administration of anti CD 4 . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Neither 1 . 6 nM PMA , nor immobilized anti CD 5 mAb were mitogenic as a sole stimulus . mAb identifying CD 4 , CD 7 , CD11a , CD 18 , and major histocompatibility complex class 1 molecules were not comitogenic with PMA . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Frozen sections were additionally stained for Leu 1 ( CD 5 ) , Leu 2a ( CD 8 ) , Leu 3a+b ( CD 4 ) , Leu 4 ( CD 3 ) , and Leu 14 ( CD 22 ) . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
In the CD 4 CD8+TcR2+ subset there was a remarkable heterogeneity of CD 5 expression . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Polymorphism of the CD 4 and CD 5 differentiation antigens in cattle . ^^^ Monoclonal antibodies ( mAbs ) specific for bovine CD 4 and CD 5 antigens have been found to identify polymorphic determinants on these molecules . ^^^ Sequential immuno precipitation experiments together with family studies showed that the allotypes of CD 4 and CD 5 are both inherited in a simple Mendelian manner and are co dominantly expressed . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
In this work , we have studied the effect of the steroid hormone 17 beta estradiol ( E 2 ) on the different subsets of CD 4 / CD8 double negative ( DN ) thymocytes by analyzing the expression of CD 5 , CD 3 epsilon and of several 5 beta gene family products of the T cell antigen receptor ( TCR ) . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
A majority of the cells from peripheral blood coexpressed the antigens against MAbs CD 11 , CD 13 , and CD 33 but did not express the antigens against CD 1 , CD 3 , CD 4 , CD 5 , CD 8 , CD 19 , CD 20 , CD 21 , CD 41 and 42 , and glycophorin A . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
In the synovial tissue and synovial fluid of RA patients there was an increased percentage of cells expressing HLA DR , beta 2 microglobulin receptors , CD 25 , CD 5 , CD 4 , and Thy 1 , but the proportion of CD8+ cells was significantly decreased compared with that seen in peripheral blood . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Whereas CD 7 expression was increased 78 + / 25 % by 0 . 5 microM ionomycin , expression of CD 25 ( IL 2R alpha ) , class 2 MHC , 4F2 , transferrin receptor , CD 2 , CD 3 , CD 4 , CD 5 , and CD 8 molecules was not increased . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Patients with PAPS ( n = 20 ) were found to have increased total B cells , as well as CD 5 + B cells , in their peripheral blood , but normal total lymphocytes , as well as CD 4 and CD 8 T lymphocytes , compared to normal controls . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The cellular infiltrates for the surface phenotypic markers for alpha / beta and gamma / delta T cell receptors , CD 4 , CD 8 , CD 45 , and CD 5 were examined in lip biopsy specimens from two patients with primary Sjgren ' s syndrome , six with secondary Sjgren ' s syndrome , and seven healthy controls . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
This evidence suggests that CVS 5 , CVS 4 and CVS 8 recognize the equine homologues of CD 5 , CD 4 and CD 8 , and that the characteristics of these antigens are similar to those of other species . . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Removal of plasma from whole blood by washing them before labelling the lymphocytes with fluorescein conjugated antibodies reduced the proportion of CD5+CD19+ cells and increased the proportions of CD16+ CD 57 and CD16+ CD57+ cells , as compared with those measured without washing , but did not change the proportions of CD5+ CD 19 , CD 5 CD19+ , CD4+ CD 8 , CD 4 CD8+ and CD 16 CD57+ cells . ^^^ Removal of plasma from whole blood also reduced the fluorescence intensity of CD 4 and CD 5 antigens and increased that of CD 8 , CD 16 , CD 19 and CD 57 antigens on each lymphocyte subsets . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Marked differences were found in the percentage and distribution of lymphocyte subsets ( CD 5 , CD 4 , CD 8 , T 19 , CD 45 , and CD45R cells ) in hemal nodes compared to those in mesenteric lymph nodes and blood . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
We have examined the functional heterogeneity of 43 monoclonal antibodies which recognised CD 1 , CD 2 , CD 4 , CD 5 , CD 6 or CD 8 . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
To investigate the role that each of the T cell subsets may have in the pathogenesis of EAS , LEW rats sensitized with WF SMG homogenate were injected with monoclonal antibodies to deplete or inactivate , in vivo , the CD 4 , CD 5 ( OX 19 ; pan T lymphocyte ) , CD 8 , or RT 6 ( 70 % of peripheral T cells ) T cell populations . ^^^ Treatment with the OX 8 ( CD 8 ) , OX 19 ( CD 5 ) , or W3 / 25 ( CD 4 ) only partially reduced in vivo the respective splenic or lymph node T cell subsets when analyzed on Day 14 , while treatment with DS4 . 23 ( anti RT 6 ) resulted in greater than 95 % depletion of RT6+ spleen and lymph node T cells . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
N methyl N nitrosourea induces murine CD 4 8+ T lymphomas that express high levels of J11d and low levels of CD 5 antigens , a phenotype characteristic of immature CD 4 8+ thymocytes . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The staining pattern of Th 5 in the thymus was apparently different from those with other T cell markers ( Thy 1 , CD 3 , CD 4 , CD 5 , CD 8 ) including J11d , Pgp 1 , IL 2R , and 3A10 ( TCR gamma delta ) . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The majority of early CD3+ spleen cells ( 21st 28th week ) expressed TCR alpha beta but not TCR gamma delta , although a significant proportion of these cells was still lacking CD 4 , CD 8 , and CD 5 differentiation antigens , suggesting their immaturity . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The monoclonal antibodies used in this study were SBU T 1 ( CD 5 ) , SBU T 4 ( CD 4 ) , SBU T 8 ( CD 8 ) , SBU 2 ( anti DR antibody ) , and E 53 which are reported to be sheep homologues of human T 1 , T 4 , T 8 , HLA DR , and pan B cell antibodies , respectively . ^^^ Not only did CD 5 labeled cells show a high percentage in each regional lymph examined , but the percentage of CD 4 labeled cells was consistently higher than that of CD 8 labeled cells . ^^^ The sum of the percentages of CD 4 and CD 8 labeled cells was less than the percentage of CD 5 labeled cells , indicating the presence of a minor T cell subpopulation which was CD5+ , CD 4 , and CD 8 . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The phenotype was : Thy 1+ , Lyt 1+ ( CD 5 ) , triple negative ( CD 4 , CD 8 , and CD 3 ) , B220+ ( Ly 5 , CD45RA ) , positive for IL 3 receptors , but not IL 2 receptors , and positive for antibodies that react with a putative constant or framework portion of DTH initiating factors such as anti PC 1 F antibodies and 14 30 mAb . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The IL 2 treatment resulted in the expansion of Thy 1+ / , CD 4 , CD 8 , CD 3 , Fc gamma RII+ , CD 5 ( Lyt 1 ) , HSA , Pgp 1+ , Mel 14 population . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
In addition , other markers such as CD 4 and CD 5 were induced by IL 2 in this cell line . . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Transmembrane signaling of normal human T cells was explored with mAbs directed at TCR , CD 2 , CD 4 , CD 5 , or CD 8 antigens and highly purified CD4+ T cells and CD8+ T cells . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Targeting pokeweed antiviral protein to CD4+ T cells by conjugating it to monoclonal antibodies reactive with CD 5 , CD 7 or CD 4 expressed on CD4+ cells , increased its anti HIV potency up to 1 , 000 fold . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Phenotypic studies of fresh isolated PP T cells demonstrate that all PP CD 4 T cells ( both Thy 1 and Thy 1+ ) express CD 3 , alpha beta TCR , and CD 5 ( Lyt 1 ) , whereas none coexpress CD 8 ( Lyt 2 ) . ^^^ Thy 1 and Thy 1+ CD 4 T cell lines generated from PP also coexpress CD 3 and alpha beta TCR , but are heterogeneous in expression of CD 5 and again do not coexpress CD 8 . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
In some clusters almost all antibodies cross reacted ( CD 2 , CD 8 ) , in others almost none cross reacted ( CD 4 , CD 5 ) and in cluster CD 6 , mAbs only reacted with buffalo but not waterbuck . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The relative molecular weight ( Mr ) of the CD 1 , CD 2 , CD 4 , CD 5 , CD 6 , CD 8 and additional molecules identified by monoclonal antibodies ( mAb ) submitted to the workshop was determined using 125I surface labelled leukocytes . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The increased percentage of surface CRP was not due to an abnormal change in major lymphocyte subset ( CD 5 , CD 4 , CD 8 , or CD 19 ) . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The phenotype of these cells were as follows : Fc gamma R+ , CD2+ , CD 5 , CD 7 , CD 3 , CD 4 , CD 1 , CD 8 , sIg , CD 20 , CD 11 , CD 13 , OKIa+ , CD 25 , CD16+ , Leu 7 . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Of the new therapies monoclonal antibodies to CD 4 and CD 5 positive lymphocytes are showing promise of marked efficacy in the short term . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
They demonstrated the T cell association antigens , CD 2 and CD 4 , but no CD 3 , CD 8 , CD 1 , CD 5 , CD 7 nor T cell antigen receptor on their cell surfaces . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
There were no changes in the percentages of cells expressing CD 4 , CD 5 , CD 8 or immunoglobulin . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Morphometric analysis revealed significant increases in numbers of cells expressing CD 5 , CD 4 , CD 8 , CD45R ( mainly B cells ) , major histocompatibility complex ( MHC ) class 2 antigens , Fc receptors ( FcR ) on macrophages ( VPM 32 ) and FcR on B cells and macrophages ( VPM 33 ) from five days post infection . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Of the cases tested , membrane CD 1 expression was found in 38 % of cases , CD 3 in 33 % , CD 4 in 50 % , CD 5 in 94 % , CD 8 in 55 % , and CD 10 in 35 % . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
CD 4 CD8 double negative ( DN ) and CD4+CD8 T cell clones were derived from splenic precursors resistant to killing by anti Thy 1 , CD 5 , CD 4 and CD 8 monoclonal antibodies and complement . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
A majority of the cells from peripheral blood coexpressed the antigens against MAbs CD 2 , CD 3 , CD 4 , CD 5 , Ti ( WT 31 ) , CD 25 , CD 38 , CD 45 , and CD 29 , but did not express the antigens against CD 1 , CD 13 , CD 14 , CD 33 , CD 36 , CD 10 , CD 19 , CD 20 , CD 21 , CD 24 , CD 41 , CD 42 , CD45RA , CD 56 , and CD 57 . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
By FMF with appropriate antibody reagents , these cells were shown to be Thy 1+ , CD 4 , CD 5 , and CD8+ and to express CD 3 and the alpha beta TCR . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Antigen specific nonresponsiveness was induced by both nonmitogenic and mitogenic anti CD 3 antibodies but not by antibodies against CD 2 , CD 4 , CD 5 , CD 8 , CD 18 , or CD 28 . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
B CLL showed heterogeneity by showing reactivity against various T cell markers such as CD 5 ( present on mature T cells ) and also CD 4 ( T helper / inducer ) , CD 8 ( T suppressor / cytotoxic ) and a very high percentage of Ia ( HLA DR ) . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Flow cytometric analysis of lymphocyte populations from lymphomas in six recipients revealed that , while all lymphomas expressed phenotypic markers of immature cortical thymocytes , i . e . , Thy 1 , Pgp 1 , Jlld , and CD 5 , they were not uniform with regard to other T cell markers , notably CD 4 and CD 8 . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Stable expression of the TCR , class 1 , and CD 5 molecules but not Thy1 . 2 and CD 4 molecules has been demonstrated , and the C6VL / 1 origin of this cell has been confirmed by Southern blot analysis using probes specific for the TCR beta chain gene . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Natural killer cell activity and the number of Leu 19 ( CD 56 ) positive cells decreased at 24 h after infusion ; significant changes in LAK activity and the number of Leu 1 ( CD 5 ) , Leu 3 ( CD 4 ) , Leu 2 ( CD 8 ) cells were not observed . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
CD 7 , CD 5 , and CD 2 were the most frequently expressed T cell antigens , and CD 2 and CD 4 were more frequently observed in children than in adults . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
PHA was mostly mitogenic for T PBL bearing the CD 3 , CD 5 , CD 7 , CD 8 and CD 25 differentiation clusters , and a low density of CD 1 and CD 4 had a small effect on human natural killer cells ( HNK ) and also did not stimulate B ( CD 19 ) and HLA DR+ PBL . ^^^ The mitogenic effect of PWM was evident on CD 3 , CD 5 , CD 7 , CD 4 , CD 25 and CD 8 , but not on HNK , HLA DR and CD 19 B PBL , which presumably had already differentiated into antibody secreting cells . ^^^ After MLC stimulation all T , B and HNK PBL subsets tested were increased , but the cells bearing CD 1 , CD 4 , CD 5 , CD 7 , CD 25 , HNK , CD 19 and HLA DR had the greatest proliferation with respect to the unmixed control PBL . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Monoclonal antibody studies performed on biopsy specimens from both patients revealed 70 % to 100 % cells staining with CD 5 , 80 % to 90 % staining with CD 4 , 30 % to 50 % staining with CD 8 , and an increase in CD 1 staining cells in the papillary dermis , indicating a predominantly helper T cell infiltrate . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The predominant cell population expressed CD 3 , CD 2 , CD 5 , and CD 4 , while results of testing for CD 8 were negative . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Using immunohistochemical methods , the authors studied the expression of pan T and majority T cell antigens ( CD 5 , CD 2 , CD 3 , TCR beta , CD 7 ) and T cell subset antigens ( CD 4 , CD 8 ) in cutaneous T cells in mycosis fungoides ( MF ) ( 177 biopsies from 124 patients ) and a variety of inflammatory lesions ( 45 biopsies from 45 patients ) . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The T cell surface antigens CD 5 and / or CD 2 and focal acid phosphatase were additional markers of this subgroup traditionally called pre T ALL , whereas thymocyte antigen CD 1 as well as CD 4 and CD 8 antigens were not expressed . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
On cryostat sections all CBCL so tested were positive for surface membrane immunoglobulins ( IgMk most often ) and B cell antigens ( CD22+ , CD37+ ) with a variable T cell reactive component identified by MoAbs against T cell antigens ( CD 2 , CD 3 , CD 4 , CD 5 , CD 8 ) . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
At relapse the leukemic cells expressed CD 1 , CD 2 , CD 5 , CD 7 , and CD 4 or CD 8 , antigens of the common thymocyte compartment . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
CD 2 , CD 3 , CD 4 , and CD 5 antigens were homogeneously expressed on all TLC in contrast to CD 6 and CD 7 antigens which were present on only a fraction of the cells in a given TLC . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
In search for agents able to complement the signals provided by BMA 030 F ( ab ' ) 2 , several antibodies directed against CD 2 , CD 4 , CD 5 , CD 6 and CD 8 were used . ^^^ However , if BMA 030 F ( ab ' ) 2 and any other of these anti CD 2 , CD 4 , CD 5 , CD 6 or CD 8 antibodies were cross linked , then proliferation of T cells occurred . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The data suggest that when anti CD 3 stimulation is suboptimal , responses can be enhanced by MAb to CD 5 or CD 28 ( Tp 44 ) or by immobilized MAb to CD 4 , CD 2 , CD11a ( LFA 1 ) , or class 1 MHC encoded gene products . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Following this one color stain the process was repeated using a different primary mouse MAb against another lymphocyte antigen ( CD 4 , Ig light chain , CD 3 , MHCII DR , CD 5 ) and fast blue BB naphthol AS MX phosphate at the last step to yield a blue product . ^^^ To achieve an intense blue in the second stain for some antigens , e . g . , CD 4 , either the MAb concentration had to be increased or two different MAbs recognizing differing epitopes of the same antigen , e . g . , T 1 and UCHT 2 for CD 5 , were applied . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The intensity of CD 5 expression on B cells was at least 10 times ' duller ' than on T cells , CD 5 ' dull ' cells were CD 3 negative , and T cells bearing the gamma delta antigen receptor did not express either CD 4 or CD 8 on their surface . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The relationship between surface molecule expression and encephalitogenicity of myelin basic protein ( BP ) sensitized cells induced by three different sensitization protocols was studied using adoptive transfer in Lewis rats . ( 1 ) In BP / CFA sensitization , CD4+ blastoid T cells showing marked upregulation of CD 4 , class 1 and 2 MHC , and IL 2 receptor molecules , but not CD 5 , CD 8 , or CD 45 , were generated after culture with BP . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The experiments reported in this paper examine the cell surface phenotype ( CD 5 , CD 4 , CD 8 , T 19 , MHC class 2 and sIg ) and cell output of lymphocyte subsets circulating through a subcutaneous lymph node in the sheep fetus , in an environment unaffected by foreign antigen and circulating immunoglobulins . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The immunological marker profile of MKB 1 indicated that unlike a myeloid phenotype of the original leukemic cells , the cells were positive for CD 3 ( both cell surface and cytoplasm ) , T cell receptor ( TcR ) alpha / beta heterodimer , CD 4 , CD 5 , CD 7 , CD 10 , CD 57 ( Leu 7 ) , SN 1 and the cytoplasmic TcR beta chain . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
CD 4 ( helper inducer ) cells dropped , rosettes , CD 5 , CD 8 , CD 16 ( NK ) and T HLA DR ( activated ) number of cells did not change significantly . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Neither Thy 1 nor CD 5 ( Ly 1 ) , H 2 K , H 2 D , LFA 1 ( all positive ) nor CD 4 ( L3T4 ) or MEL 14 ( both negative ) were influenced by this treatment . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Immunocytochemistry revealed the pale cells to bear T cell markers ( MT 1 , CD 5 , CD 8 or CD 4 ) and IgM positive cell distribution . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Stimulation was not blocked by CD 4 , CD 5 , CD 6 , CD 7 , or CD 45 MoAbs , despite high levels of expression of these antigens on the TCC . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Cryostat sections of normal human adult gastrointestinal mucosae were studied by double label immunofluorescence with antibodies to CD 3 , CD 4 , CD 8 , CD 5 and CD 6 , in parallel with antibodies beta F 1 and TCR delta 1 against beta chains and delta chains of the T cell receptor ( TcR ) types TcR 2 ( alpha / beta ) and TcR 1 ( gamma / delta ) , respectively . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Heterogeneity among the 18 clones was detected with respect to the expression of the CD 4 , CD 5 and CD 8 antigens : one clone was CD4+ , nine clones were CD5+ and two clones were CD8+ . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Autologous mixed lymphocyte reaction ( AMLR ) and phenotypical composition of circulating lymphocytes obtained from nine subjects with untreated hepatocellular carcinoma ( HCC ) ; three HCC patients locally treated by means of intraarterial chemoembolization ; six subjects with gut derived carcinoma ( GDC ) ; nine chronic active liver disease patients ( CALD ) , and 14 normal controls have been evaluated , using monoclonal antibodies ( MAB ) against CD 5 , CD 8 , CD 4 glycoproteins and anti LAK 1 molecule , a novel 120 KD surface antigen that is present on the membrane of large granular lymphocytes , by means of classical indirect immunofluorescence technique . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
These leukemic blasts did not express both T cell lineage antigens which are detectable by monoclonal antibodies , T 6 ( CD 1 ) , T 11 ( CD 2 ) , T 3 ( CD 3 ) , T 4 ( CD 4 ) , T 1 ( CD 5 ) , Tp 40 , Leu 9 ( CD 7 ) , T 8 ( CD 8 ) , and B cell lineage antigens which are detectable by monoclonal antibodies , B 4 ( CD 19 ) , B 1 ( CD 20 ) , B 2 ( CD 21 ) and J 5 ( CD 10 ) . ( ABSTRACT TRUNCATED AT 400 WORDS ) . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Lymphoid cell subsets ( CD 5 , CD 4 , CD 8 , IgA 1 , IgA 2 , IgM , IgD , IgG , and IgE positive cells ) in the lamina propria , and HLA DR antigens on the epithelia were studied in 7 patients with FPC . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Virtually all TCR gamma / delta+ thymocytes / lymphocytes expressed CD 7 , CD 2 , and CD 5 but were heterogeneous with respect to their expression of CD 1 , CD 4 , CD 8 , CD 28 , CD11b , CD 16 , and Leu 7 . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Dendritic epidermal T cells ( DETC ) are CD45+ , Thy 1+ , CD 5 , CD 8 , CD 4 murine lymphocytes that express surface bound CD 3 antigens associated with T cell receptor gamma / delta heterodimers . ^^^ Although a portion of proliferating DETC expressed CD 8 antigens , essentially none bore detectable amounts of surface bound CD 4 or CD 5 antigens , or both . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
TKS 1 cells were not reactive with any of the following antibodies : anti OK M 1 ( CD11b ) , Leu M 2 , Leu M 3 ( CD 14 ) , Leu M 4 , Leu 1 ( CD 5 ) , Leu 2 ( CD 8 ) , Leu 3 ( CD 4 ) , Leu 4 ( CD 3 ) , Leu 7 and Leu 11 ( CD 16 ) . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Whereas small lymphocytes displayed a CD19+ ; CD24+ ; CD37+ ; CD5+ phenotype , the blastic population exhibited , besides CD 13 , CD 14 and CD 15 positivity , which is usually noted in such a monoblastic leukemia , definite CD 9 , CD 10 , CD 22 , CD 24 , CD 37 , CD 5 and CD 4 staining . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
To investigate whether the presence or absence of tissue eosinophilia is related to the immunophenotype of the T cells , we studied 43 cases of HD ( 28 nodular sclerosing , ten mixed cellularity , and five unclassifiable ) for the relative numbers of lymphocytes positive for CD 2 , CD 3 , CD 4 , CD 5 , CD 8 , CD 25 , CD 38 , T 9 , TQ 1 , HLA DR , and beta F 1 , and for the number of eosinophils in tissue sections . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Although the staining intensity of other T cell antigens ( CD 4 & CD 5 ) , B cell antigens ( CD 19 , CD 21 & CD 37 ) , activation antigens ( Ki 1 ) and nuclear proliferation antigen ( Ki 67 ) was slightly weaker as compared with frozen sections , this could be corrected by increasing the monoclonal antibody concentration . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The tumor cells expressed , CD 2 , CD 3 , CD 4 , CD 5 and CD 7 antigens , which corresponded to the phenotype of helper inducer T lymphocytes . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Here a time dependent decrease of labelling by CD 2 ( OX 34 ) , CD 8 ( OX 8 ) , CD 4 ( ER 2 ) , and CD 5 ( OX 19 ) was observed . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Vitamin B 6 status was positively related to percentages of T cell subsets : the lowest percentages of CD 5 and CD 4 cells were observed in the low B 6 status group ( 50 . 6 and 32 . 6 per cent ) and the highest percentages in the high B 6 status group ( 62 . 0 and 41 . 0 per cent ) , with intermediate values in the medium group ( 57 . 6 and 39 . 5 per cent ) . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Complete inhibition of MRBC formation was obtained with monoclonal antibodies against CD 5 , CD 3 and CD 8 while partial inhibition was observed with anti Ia and no activity with CD 4 and CD 10 antibodies . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Moreover , pretreatment with anti Thy 1 . 2 antibody or anti L3T4 ( CD 4 ) antibody was more effective than pretreatment with anti Lyt 1 ( CD 5 ) antibody or anti Lyt 2 ( CD 8 ) antibody as an initial step in tolerance induction . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Phenotypical analysis was carried out by the indirect immunofluorescence technique using monoclonal antibodies specific to CD 5 ( mature T lymphocytes ) , CD 4 ( helper / inducer T lymphocytes ) , CD 8 ( suppressor / cytotoxic T lymphocytes ) , glycoproteins , and an immunoglobulin fraction from rabbit directed to membrane alpha 1 acid glycoprotein ( AGP ) that is involved in T cell activation process . ^^^ No differences were present in circulating T lymphocytes expressing CD 5 , CD 4 , and CD 8 on their membrane , whereas AGP bearing lymphocytes were significantly lower in chronic alcoholics ( 14 . 4 + / 8 . 6 ) than in controls ( 31 . 9 + / 8 . 1 ; p less than 0 . 001 ) . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Eleven or more days after tumour inoculation the proportions of tumour bearer splenic leucocytes expressing Ly 1 . 2 ( CD 5 ) , Ly 2 . 2 ( CD8a ) or L3T4 ( CD 4 ) surface antigens were significantly less than similar preparations from normal animals . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
We used enzyme ( acid phosphatase [ AP ] ) and immunohistochemical techniques and a set of monoclonal antibodies ( CD 11 , CD 5 , CD 4 , CD 19 , CD 8 , OKIa ) , including two recently developed antibodies for example , HECA 452 ( specific for an adhesion molecule on high endothelial venules ) and RFD 1 ( specific for ' active ' human dendritic cells ) to analyse the composition of the gut wall infiltrate of 10 well defined cases of chronic inflammatory bowel disease ( CIBD ) ( six Crohn ' s disease ( CD ) , four ulcerative colitis ( UC ] . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Basing on the data concerning the distribution of McAb reactivity with cells from different organs and tissues , and with tumour cell lines , on experiments on the mutual blockage and comodulation of antigens , on two colour immunofluorescence and determination of the molecular weight of the detected antigens a conclusion is made that the McAb obtained react with CD 5 , CD 2 , CD 4 , CD 6 , CD 7 , CD 8 , CD 21 and HLA DR antigens , respectively . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
In comparison to aged cross matched male controls , significant increases of absolute number of lymphocytes and of T and B cell subpopulations with significant reduction of the percentages of CD 3 , CD 4 , CD 2 , CD 5 , sIg , and CD 16 cells was found in haemophiliacs . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Granulated lymphoid cells ( CD2+ , CD7+ , CD38+ , NKH1+ , CD 3 , CD 5 , CD 4 , CD 8 , CD 25 ) are prominent in human endometrial stroma in the late secretory phase of the menstrual cycle and in early pregnancy , and may play an important role in implantation and placentation . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
These immature cells are TdT and do not express membrane CD 3 ( mCD 3 ) or TCR beta identified by beta F 1 , but show CD 7 and CD 45 positivity without CD 1 , CD 2 , CD 5 , CD 4 , CD 8 , CD 10 , and class 2 Ag . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Antigenic modulation induced by four monoclonal antibodies adsorbed on gold particles ( specificity anti CD 4 , anti CD 5 , anti CD 7 , and anti 150 kDa antigen ) : relationship between modulation and cytotoxic activity of immunotoxins . ^^^ The present study concerns the antibody induced antigenic modulation of CD 4 , CD 5 , CD 7 , and 150 kDa antigens present on cells of the CCRF CEM human T line . ^^^ Thus , the anti CD 7 monoclonal antibody ( MoAb ) was frequently internalized via the coated structures of the cell membrane , whereas anti CD 5 MoAb was rarely internalized via those structures and anti CD 4 and anti 150 kDa antigens never used this route . ^^^ The delay required for 50 % internalization of the labeled MoAb receptor complexes was 30 min . 1 h , 2 h , and 9 h for anti CD 7 , anti CD 5 , anti CD 4 , and anti 150 kDa antigen MoAbs , respectively . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The tumor cells carried the CD 3 and CD 7 T cell antigens , but were double negative for CD 4 and CD 8 and also lacked other T cell antigens ( CD 1 , CD 2 , and CD 5 ) . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
In eight cases , a variable percentage of typical Hodgkin ' s and Reed Sternberg cells showed a clear cut cytoplasmic and / or surface positivity for the T cell associated antigens CD 3 , CD 5 , CD 6 and CD 4 ( seven cases ) or CD 8 ( one case ) , but consistently lacked B cell and macrophage associated markers . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The leukemic cells were large granular lymphocytes by light and electron microscopic criteria , and had the following immunophenotype : CD2+ , DR+ , Leu7+ , NKH1+ , CD11+ , CD 3 , CD 5 , CD 4 , CD 8 , CD 16 . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Five isolates of Pseudomonas aeruginosa ( CD 2 , CD 3 , CD 4 , CD 5 , and CD 10 ) from a patient with cystic fibrosis were examined with regard to several genotypic and phenotypic characteristics to determine whether the patient was colonized with one or several distinct strains . ^^^ Isolates CD 2 , CD 3 , and CD 4 were obtained from a single sputum sample , and CD 5 and CD 10 were obtained 1 and 2 years later , respectively . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The leukaemic blasts were shown ( by immunocytochemical analysis ) to have a mature , T helper cell phenotype , i . e . , OX 19 ( CD 5 ) + / , W3 / 25 ( CD 4 ) + , OX44+ , MHC class I+ , OX 26+ , corresponding to a population comprising 5 % of normal rat medullary thymocytes . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Dual color flow microfluorimetry ( FMF ) demonstrates that MAb 22 staining has concordant distribution with pan T MAb specific for CD 3 and CD 5 and includes the CD 4 and CD 8 subsets ; other FMF studies confirm T cell specificity of MAb 22 expression by cells of hematopoietic origin . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Immunolabeling experiments showed that resident Thy 1+DEC are CD45+ , Thy 1+ , CD3+ , TcR 5 beta 8 , CD 5 , CD 4 CD 8 , CD 25 lymphocytes . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
In addition to the CD 3 T cell receptor complex , the CD 2 , CD 4 , CD 5 , CD 7 , CD 8 and CD 28 receptors mobilize cytoplasmic calcium within minutes of binding with monoclonal antibodies and additional crosslinking occurs on the cell surface . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
We have compared the requirements of the primary MLR and the responses of alloreactive , primed lymphocytes ( PL ) by inhibition studies using monoclonal antibodies ( MoAb ) directed against ( 1 ) adhesion molecules belonging to the CD 11 cluster of leucocyte antigens ( CD11a , LFA 1 ; CD11b , MAC 1 = CR 3 ; and CD11c , p 150 , 95 ) ; ( 2 ) various T cell related antigens ( CD 2 , CD 4 , CD 5 and CD 8 ) ; and ( 3 ) recombinant IL 1 beta . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
In this study , CD 4 CD 8 adult murine thymocytes were separated into subsets based on the expression of the `` heat stable antigen ' ' ( HSA ) and of Ly 1 ( CD 5 ) . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
These results indicate that ( a ) mAb CTLA 5 and 8 identify antigens on mature T lymphocytes that are similar in tissue distribution , molecular mass and function to the mammalian CD 5 antigen ; ( b ) mAb CTLA 3 , 4 and 9 detect the avian homologue of CD 8 antigen ; and ( c ) mAb CTLA 1 and 6 identify the avian homologue of CD 4 antigen . . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The validity of the method was assessed on human peripheral blood mononuclear cells by using three sets of two monoclonal antibodies : CD 8 and CD 5 , CD 3 and CD 4 , CD 11 and HLA DR . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
In peripheral blood lymphocytes , 1 / 3 of the CD3+ , CD 5 cells were positive for Leu 2a ( CD 8 ) while virtually all were negative for Leu 3a ( CD 4 ) . ^^^ Four colour flow cytometric analysis revealed a small subset of T cells positive for CD 3 and negative for CD 5 , CD 4 and CD 8 . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
From three days , small aggregates of CD 4 ( + ) , Ia ( + ) , CD 5 ( ) and IL 1 ( + ) cells were observed in the lamina propria . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Immune regulatory derangements include lymphokine induced aberrant expression of MHC Class 2 molecules on synovial tissues , the presence of a ' resistant ' subset of B cells ( CD 5 + ve ) , failure of anti idiotypic control of autoantibodies ( not well established as yet in rheumatoid arthritis ) , and defective immune suppression , revealed by low counts in synovial fluids of a suppressor inducer subset of CD 4 + ve T cells . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Comparison of the lymphocyte subsets in the BALF with those of the peripheral blood revealed much higher values for the ratios of each Leu 3a+ ( CD 4 ) , Leu 3+8 , and Leu 2+15 cells , while the ratios of Leu 1+ ( CD 5 ) , Leu 2a+ ( CD 8 ) , Leu 7+ , Leu 8+ , Leu 10+ , Leu 11a+ ( CD 16 ) , Leu 12+ , and Leu 2+15+ cells were low in the BALF . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Antibodies binding to a large subset of T cell differentiation antigens , including CD 2 , CD 4 , CD 5 , CD 6 , CD 7 , CD 8 , Tp 44 , and CDw 18 , cause an increase in the cytoplasmic calcium concentration [ ( Ca2+ ] 1 ) after the antigens are crosslinked on the cell surface . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The immunologic phenotype of PTC , as revealed on frozen tumor tissue sections , comprised the expression of CD 5 ( T 1 ) , CD 4 ( T 4 ) , and HLA DR , but not CD 8 ( T 8 ) and CD 2 ( T 11 ) and suggested an affiliation to the T cell system . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
THP 6 cells were positive for CD 7 and CD 5 antigens and terminal deoxynucleotidyl transferase , but negative for CD 2 , CD 1 , CD 4 , CD 8 , CD 10 , cytoplasmic and surface CD 3 and HLA DR antigens , suggesting a precursor T cell line . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Antibodies directed against Leu 1 / T1 ( CD 5 ) , Leu 3 / T4 ( CD 4 ) , LFA 3 , and class 1 ( HLA A , B , C ) and class 2 ( HLA DR , DQ ) major histocompatibility complex molecules had no effect on either the generation or the effector function of Ts . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
A preponderance of T lymphocytes , with approximately equal numbers of cells expressing CD 5 , CD 4 and CD 8 antigens , was found . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
This response was noted as soon as 2 h after addition of rIL 2 . 2 h rIL 2 activated plastic adherent lymphocytes were 90 98 % LGL , expressed surface markers characteristic of rat NK cells ( OX 8 [ CD 8 ] + , asialo GM 1 , laminin+ , OX 19 [ CD 5 ] , R 1 3B3 [ CD 5 ] , W3 / 25 [ CD 4 ] , OX 39 [ CD 25 ] , Ia , and Ig ) , and expressed very high levels of cytotoxicity against YAC 1 target cells . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Detailed immunological analysis demonstrated that the vast majority of these cells expressed T cell associated antigens ( i . e . , CD 7 , CD 5 , CD 2 , CD 4 , and to a lesser extent , CD 8 ) . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The sustained loss of CD 4 and CD 8 surface expression on DP cells is a selective event because CD 5 expression is enhanced , H 2 expression is unchanged , and CD 3 expression is only transiently diminished by PMA stimulation . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
We investigated the phosphorylation of CD 2 , CD 3 , CD 4 , CD 5 , CD 7 , CD 8 , CD 28 ( Tp 44 ) , CD 43 ( sialophorin , gp 115 ) , and LFA 1 after incubation of human PBMC with the ( PKC ) activator PMA . ^^^ These proteins were chosen for their role in transmembrane signal transduction ( CD 2 , CD 3 , CD 5 , CD 28 , CD 43 ) , cell cell interaction and adhesion ( CD 2 , CD 4 , CD 8 , and LFA 1 ) , or involvement in immunodeficiency states ( CD 43 , CD 7 ) . ^^^ PMA induced rapid hyperphosphorylation of CD 5 , CD 7 , and CD 43 , but not of the LFA 1 alpha chain , and induced the phosphorylation of CD 3 , CD 4 , CD 8 and of the LFA 1 beta chain . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The cells , which expressed the T cell associated markers CD 4 and CD 5 , were positive for HLA DR , epithelial membrane antigen , and CD 30 ( Ki 1 antigen ) . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
In this study we analysed the efficacy of different monoclonal antibodies ( MoAb ) WT 32 ( CD 3 ) , OKT 4 ( CD 4 ) , T 101 ( CD 5 ) , WT 1 ( CD 7 ) , and WT 82 ( CD 8 ) with respect to their cytotoxicity to T cells either as immunotoxin ( IT ) or in combination with complement . ^^^ The natural killer ( NK ) activity , as measured by cytotoxicity to K 562 , was hardly depressed by anti CD 3 , anti CD 4 , anti CD 5 , and anti CD 8 , but was eliminated by anti CD 7 . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The relative proportions of CD 5 , CD 4 , CD 8 , SBU T 19 and surface immunoglobulin ( sIg ) positive lymphocytes in normal sheep livers were determined by flow cytometry analysis of isolated liver leucocytes and compared to lymphocyte subpopulations found in peripheral blood and hepatic lymph nodes . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The efficacy of the monoclonal antibodies ( MoAbs ) WT 32 ( CD 3 ) , OKT 4 ( CD 4 ) , T 101 ( CD 5 ) , WT 1 ( CD 7 ) and WT 82 ( CD 8 ) conjugated to ricin A chain was expressed by the extent of protein synthesis inhibition of four leukaemic T cell lines ( CEM , GH 1 , Jurkat and HPB ALL ) . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Several leukocyte antigens that were not found initially on LCs did not appear , including B 220 anti B cell , 33D1 anti dendritic cell , and CD 4 , CD 5 , CD 8 T cell specificities . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
With our system , a wide variety of antigens are detected in plastic sections without trypsinization or prolonged embedding procedures ; pan B ( CD 19 , CD 22 ) , pan T ( CD 7 , CD 5 , CD 3 , CD 2 ) , T subset ( CD 4 , CD 8 , CD 1 , CD 25 ) markers as well as surface immunoglobulin and markers for myeloid and mononuclear phagocyte cells are preserved . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The surface phenotypes ( CD 1 , CD 4 , CD 5 , CD 8 , SBU T 19 , MHC class 1 , MHC class 2 , and sIg ) of cells in blood , lymph nodes , and lymph were determined to examine simultaneously the distribution of lymphocyte subsets circulating in blood , afferent lymph , and efferent lymph of a peripheral lymph node . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The densities of CD 3 , CD 4 , CD 5 , CD 8 and sIgM lymphocyte antigens were the same on patients ' lymphocytes as on lymphocytes from healthy subjects . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Some of the major sheep antigens , including CD 5 , CD 4 , CD 8 , SBU T 19 , Pgp 1 , LCA and the MHC antigens , are described in detail . . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Phenotypic analysis showed that the hybrids could be grouped as follows : a high frequency expressing CD 25 ( IL 2 receptor ) , human T 200 , HLA class 1 alpha and beta 2microglobulin , and reacting with the mAb H 207 and 12E7 ; an intermediate frequency expressing CD 1 and CD 2 ; and a low frequency expressing CD 3 , CD 4 , CD 5 , CD 7 , CD 8 and CD 9 . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
We demonstrate that alloimmunization of BN rats can result in either OX19+ ( CD5+ ) or OX 19 ( CD 5 ) cytolytic alloselective lymphocytes and show that the OX 19 ( CD 5 ) cytolytic cells are OX34+ W3 / 25 ( CD 4 ) OX8+ ( CD8+ ) lymphocytes not exposing surface Ig . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
We have demonstrated that the most aggressive IL 2 dependent killer cells ( directed against leukemic and solid cancer targets ) exhibited LGL morphology and expressed NK cell associated antigens NKH 1 and CD 16 , but not T cell associated antigens CD 3 , CD 4 , CD 5 , or CD 8 . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
In contrast , the cells which express high levels of CD3 / Ti alpha / beta co express high levels of CD 5 and are predominantly contained in the more mature single positive cells which express either CD 4 or CD 8 . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The immunological phenotype of the lymphoma resembled that of immature T cells present in the normal thymus cortex positivity for CD 1 , CD 2 , CD 4 , CD 7 , CD 38 and terminal deoxynucleotidyl transferase ; faint positivity for CD 5 and in the second specimen for CD 3 ; negativity for CD 6 and MHC class 1 antigen . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
These patterns of CD3 / beta F 1 expression , along with the patterns of CD 2 , CD 4 , CD 5 , CD 7 , and CD 8 antigen expression in these neoplasms , indicate that T cell lymphomas can manifest phenotypes not apparently reflective of normal T populations and suggest the presence of abnormal gene expression in these malignancies . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Immunohistological analysis with a range of monoclonal antibodies showed the PTC of our case to be CD 5 ( T 1 ) + , CD 4 ( T 4 ) + , CD 3 ( T 3 ) , CD 8 ( T 8 ) , CD 2 ( T 11 ) , and CD 25 ( TAC ) , but HLA DR+ and transferrin receptor positive . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The atypical lymphocytes were positive for CD 3 , CD 4 , CD 5 , CD 7 and HLA DR , and negative for CD 8 . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Surface marker analysis revealed the blasts to be CD 2 , CD 3 , CD 4 , CD 5 , CD7+ , CD 8 , CD 10 , CD 13 + / , CD 19 , CD 20 , CD 25 , CD33+ and human leukocyte antigen DR ( HLA DR+ ) . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Peripheral blood mononuclear cells were quantified for the subsets of CD 4 , CD 8 , and CD 19 lymphocytes by using CD45RA ( 2H4 ) , CD 29 ( 4B4 ) , CD 57 , CD 5 , CD 10 , Leu 8 , HLA DR , and TCR gamma delta 1 monoclonal antibodies and dual color immunofluorescence . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Anti CD 5 also precipitated the kinase from various T cells irrespective of the expression of TcR zeta / CD3 or CD 4 . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
These horses , however , maintained a residual population of CD2+ T lymphocytes [ 15 ( + / 3 ) % of pretreatment numbers ] that did not express CD 5 but expressed either CD 4 or CD 8 . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The expression or in vitro induction of CD 13 and / or CD 33 antigens correlated with the immaturity of these neoplastic T cells , since it was observed in all 11 CD7+ CD 5 CD 2 and CD7+ CD5+ CD 2 , and some CD7+ CD5+ CD2+ ( CD 3 CD 4 CD 8 ) cases , but not in CD 3 + / CD4+ CD8+ or CD3+ CD4+ CD 8 cases . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
No changes were noted for CD 3 , CD 4 , CD 5 , CD 14 , CD 16 , CD 19 , CDw49a , or TCR delta . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Murine Thy 1+ , TcR 5 gamma 3 / V delta 1+ dendritic epidermal T cells ( DETC ) differ from most other T cell subsets by the absence of CD 4 and CD 8 antigens as well as the lack of CD 5 expression . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
CD34bright thymocytes were CD 33 / dull and were negative for CD 38 , CD 2 , and CD 5 as well as for the lineage markers CD 3 , CD 4 , and CD 8 ( T cells ) , CD 19 and CD 20 ( B cells ) , CD 56 ( NK cells ) , glycophorin ( erythrocytes ) , and CD 14 ( monocytes ) . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
In sheep at the asymptomatic stage , depending on the extent of progression of the disease , the proportions of CD 2 ( + ) , CD 4 ( + ) , CD 8 ( + ) , and gamma delta TCR ( + ) T cells that coexpressed CD 5 decreased , but CD5+ sIgM+ cells as well as CD 5 sIgM+ cells increased for a period . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
To study other mucosa associated T cell populations , we examined T cell subsets separated according to expression of alpha beta T cell receptor , CD 4 , CD 5 , CD 8 , Thy 1 and B 220 in the lung and the female genital tract ( FGT ) of adult MRL lpr , C3H lpr and C3H gld mice . alpha beta T cell accumulation was detected in both the FGT and the lungs of lpr and gld mice but , in contrast to the spleen and LN , equal proportions of DN B220+ and CD4+ of CD8+ ( single positive , SP ) B 220 T cells were observed in these sites , and the T cells had an increased expression of Thy 1 and CD 5 . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Glomerular accumulation of CD 5 positive T cells [ 2 . 45 + / 0 . 21 cells per glomerular cross section ( c / gcs ) , normal 0 . 18 + / 0 . 10 c / gcs ] , CD 4 positive T cells , ( 1 . 87 + / 0 . 46 c / gcs , normal 0 . 14 + / 0 . 08 c / gcs ) , and macrophages ( 22 . 7 + / 5 . 9 c / gcs , normal 0 . 05 + / 0 . 05 c / gcs ) , together with the appearance of multinucleated giant cells ( 0 . 42 + / 0 . 15 c / gcs , normal 0 c / gcs ) suggested a DTH like reaction in glomeruli . ^^^ Sensitized rats given anti GBM globulin were treated with monoclonal anti CD 5 or anti CD 4 antibodies in a protocol which prevented cutaneous DTH to sheep globulin without altering the humoral immune response . ^^^ Both treatments significantly reduced glomerular accumulation of CD 5 and CD 4 positive T cells at day 10 . ^^^ Crescent formation was significantly reduced ( CD 5 treated , 13 + / 4 % of glomeruli affected ; P < 0 . 001 ; CD 4 treated 13 + / 3 % of glomeruli affected , P < 0 . 001 ) compared to rats treated with an isotype matched irrelevant monoclonal antibody . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The tumor cells were pleomorphic medium sized cells that expressed a range of T cell specific antigens , including CD 2 , CD 3 , CD 4 , CD 5 , CD 6 , CD 7 , and beta F 1 . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
This artifact can result in the apparent coexpression of CD 4 and CD 8 ( observed in lymphoblastic processes ) or of CD 5 and CD 20 ( characteristic of chronic lymphocytic leukemia ) in normal persons , leading to an erroneous diagnosis . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The temporal and spatial pattern of leukocyte infiltration was characterized immunocytochemically using monoclonal antibodies against CD 5 , a pan T cell marker , against CD 4 and CD 8 for subtyping of T lymphocytes , and ED 1 , a marker for macrophages . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Tissue sections were tested by peroxidase antiperoxidase method , using the following monoclonal antibodies : OX 19 ( CD 5 ) , W3 / 25 ( CD 4 ) , OX 8 ( CD 8 ) , OX 6 ( Ia ) , OX 33 ( LCA ) and OX 39 ( CD 25 ) . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
A sustained decrease in the number of CD 3 , CD 4 , CD 5 , and CD 8 bearing lymphocytes persisted for 2 months after treatment ( p < 0 . 05 ) . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The leukemia cells expressed CD 2 , CD 6 , CD 7 , CD13low , CD 56 , beta chain of IL 2 receptorlow ( IL 2R beta ) , and HLA DR antigens , but not other pan T ( CD 5 , CD 3 , CD 4 , and CD 8 ) ; pan B ( CD 10 , CD 19 , CD 20 , and CD 24 ) ; natural killer ( NK ) ( CD 16 , CD 57 ) ; or myeloid ( CD 33 ) antigens . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
In the absence of gp 120 , CD 4 displayed high association with CD 3 , CD 5 , CD45RC , CD 25 , CD 28 , CD 44 , and CD 53 ; weak association with CD 2 , CD 38 , CD45RB , CD62L , and CD 26 ; and no association with CD45RA , CD45RO , CD11b , CD11a , CD 54 , CD 7 , CD 48 , CD 98 , CD 59 CD55 , HLA class 1 and class 2 molecules . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The cell line with the highest level of binding was PER 423 ( Kees et al , Leukemia Res 1993 ; 17 : 51 59 which has the phenotype CD7+ , CD56bright , CD 2 , CD 4 , CD 5 , CD 8 , CD 16 , has rearranged T cell receptor beta chain genes , expresses cytoplasmic CD 3 and is strictly dependent on interleukin 2 ( IL 2 ) for proliferation . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Murine Thy 1+ , TCR 5 gamma 3 / V delta 1+ dendritic epidermal T cells ( DETC ) express CD 2 antigens , but differ from most other T cell subsets in their absence of CD 4 , CD 5 , and CD 8 antigens . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
In addition to CD 4 , jacalin interacts with the CD 5 molecule . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The expression of other differentiation molecules was unaffected , except for CD 1 , CD 4 , and CD 5 , which were either decreased or absent in most of these mutants . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
T cells were observed in plaques of their aortic arches ( CD 5 positive , 11 . 1 + / 7 . 3 cells / mm2 ; CD 4 positive , 9 . 9 + / 4 . 9 cells / mm2 ) by immunofluorescence using monoclonal anti rabbit CD 5 and CD 4 antibodies . ^^^ No CD 4 or CD 5 positive cells were observed in their plaques . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The involvement of T cells in the early cellular events in atherosclerosis was studied in rabbits fed a 1 % cholesterol diet by use of specific monoclonal anti rabbit CD 5 and CD 4 antibodies . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
By a two color flow cytometric analysis , Mac1+ lymphocytes were demonstrated to be TCR alpha beta intermediate+ , TCR gamma delta , CD3intermediate+ , CD 4 , CD 8 , Thy 1 , CD 5 , and B 220 . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
On immunohistochemical examination , Ki 1 , HLA DR , CD 25 ( IL 2 receptor alpha ) , CD 122 ( IL 2 receptor beta ) , CD 4 , CD11c and CD 68 were all positive in the tumor cells , whereas CD1a , CD 3 , CD 5 , CD 8 and CD 19 were negative . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The relative density of lymphocyte CD 3 , CD 4 , CD 5 , CD 8 , CD 20 , CD 23 , CD 28 , CD 38 , CD45RA , CD45RO , CD 57 and HLA DR antigens was measured as antibody binding capacity ( ABC ) in 58 blood donors aged 19 66 years . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The immunological behaviour of the host was assessed through the determination of lymphoid populations ( CD 2 , CD 3 , CD 4 , CD 5 and CD 8 ) and natural killer cells were studied with monoclonal antibodies CD 3 and CD 16 . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Expression patterns of non lineage specific markers ( terminal deoxynucleotidyl transferase ( TdT ) , CD 34 , and HLA DR ) , B lineage markers ( CD 10 , CD 19 , CD 20 , and CD 22 ) , T lineage markers ( CD 1 , CD 2 , CD 3 , CD 4 , CD 5 , CD 7 , and CD 8 ) , and cross lineage myeloid markers ( CD 14 , CD 15 , and CD 33 ) were compared at diagnosis and relapse . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Immobilized mAb identifying CD 4 , CD 7 , or LFA 1 were not co mitogenic with either mAb 9 . 3 or one of the anti CD 5 mAb . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Generation and characterization of monoclonal antibodies against rabbit CD 4 , CD 5 and CD11a antigens . ^^^ We describe in this report the production and characterization of monoclonal antibodies ( mAb ) to the rabbit homologues of CD 4 , CD 5 and CD11a antigens , and their use for phenotypic analysis of rabbit lymphoid cell lines . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
T antigens CD 3 , CD 4 and CD 5 were not detected , the CD 8 was faintly expressed . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The atypical lymphoid cells were positive for CD 19 , CD 20 , CD 22 and HLA DR but negative for CD 3 , CD 4 , CD 5 , CD 10 , CD 43 , CD45RO and CDw 75 . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
CD 4 , CD 8 , CD 2 and CD 5 ) . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Flow cytometry analysis revealed that these cells express CD 45 , CD 56 , CD 2 , CD 7 , CD11a , CD 18 , CD 69 and the intermediate affinity ( p 70 ) IL 2 receptor ( IL 2R ) but not CD 57 , CD 16 , CD 3 , CD 4 , CD 5 , CD 8 , CD45RA , CD 25 , or the high affinity p 55 IL 2R . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Phosphoaminoacid analysis of the in vitro phosphorylated proteins and Western blot analysis of the immunoprecipitates with an antiphosphotyrosine mAb show that , in contrast with other lymphocyte receptors ( CD 3 , CD 4 , IL 2R ) , CD 5 coimmunoprecipitates a serine kinase activity . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The T CLL cells coexpressed antigens detected by MAbs CD 2 , CD 3 , CD 4 , CD 5 , Ti ( TcR alpha / beta ; WT 31 ) CD 45 and CD45RA , but did not express any other antigens including CD 1 , CD 8 , CD 29 , and TCR gamma / delta , Ti gamma A and TQ 1 . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
By flow cytometric analysis with both rabbit CD 5 and CD 4 MoAbs , a decrease of the CD4+ and CD5+ subpopulations was observed in the spleen and mesenteric lymph nodes . . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Activities found in four lots each of horse ATG ( ATGAM , Upjohn ) , rabbit and horse ATG ( thymoglobulin and lymphoglobulin , Merieux ) , horse ALG ( Minnesota ) , and rabbit ATG ( Fresenius ) have been compared for CD 2 , CD 3 , CD 4 , CD 5 , CD 7 , CD 8 , CD11a , CD 18 , CD 28 , CD 44 , CD 45 , and TCR alpha / beta antigens . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Also , both trophoblast and decidual cells caused no significant changes in the expression of Thy 1 , CD 5 , CD 4 , CD 8 , CD 3 , CD 25 , CD 44 , and L selectin by the thymocytes . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Antibodies to gamma delta T cell receptor , CD 2 , CD 3 , or CD11a were also inhibitory , whereas antibodies to alpha beta T cell receptor , CD 4 , CD 5 , and CD 8 had no effect . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The immunophenotypical analysis of lymphoma revealed that the tumor expressed CD 2 , CD 3 , CD 4 , CD 5 , CD 25 and HLA DR . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
At 6 and 24 h after intradermal injection of 10 ( 9 ) mol oIL 8 , there was intense accumulation of neutrophils , and very mild accumulation of eosinophils , CD 5 , CD 4 and T 19 ( a gamma delta TCR subset ) cells but not CD 8 cells . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The NTCL patients presented clinically with lethal midline granuloma , had histologic findings of tumor necrosis and angioinvasion , and had a peculiar CD2+ , Leu 4 , CD 3 epsilon+ , CD 5 , CD7+ , CD45RO+ , CD 4 , CD 8 , beta F 1 , T cell receptor ( TRC ) delta 1 , CD56+ phenotype . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Thalidomide does not perturb CD 2 , CD 4 , CD 5 , CD 8 , HLA DR , or HLA A , B , C molecules in vitro on the membranes of cells with immune potential . ^^^ Thalidomide did not modify : ( a ) adhesion and / or signal transducing molecules such as CD 2 , CD 4 , CD 5 and CD 8 , or ( b ) molecules that facilitate antigen presentation such as HLA DR , HLA A , HLA B , or HLA C . . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
TCR / CD3 induced tyrosine phosphorylation of the intracellular enzyme phospholipase C gamma 1 and the surface receptor / substrates CD 5 and CD 6 was unaffected by virus infection , whereas augmented responses normally observed after the co ligation of CD 4 with TCR / CD3 on T lymphocytes were absent in HIV 1 infected H 9 cells . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Our results demonstrate that whereas expression of major histocompatibility complex ( MHC ) molecules , CD 45 , Mac 1 , LFA 1 , B cell markers , macrophage markers and some T cell markers ( as CD 2 , CD 4 and CD 8 ) did not undergo changes in culture , the level of expression of the adhesion molecules VLA 4 and ICAM 1 , and the T cell markers CD 5 , CD 25 and Thy 1 increased after 14 h incubation at 37 degrees C . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Results obtained showed that the majority of the CD3+ dendritic epidermal cells are CD45+ , CD2+ , TCR alpha beta , major histocompatibility complex class 2 , Thy 1 , asialo GM 1 , CD 4 , CD 5 , and CD 8 lymphocytes . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Other markers were occasionally expressed , such as CD 38 , CD45RO , CD 23 , CD 15 , CD 4 , CD 5 , and CD 10 ( expressed on more than 20 % of the hairy cells in 44 % , 25 % , 21 % , 18 % , 12 % , 10 % , and 5 % of evaluated cases , respectively ) . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Comparative two dimensional analysis of CD 2 , CD 3 , CD 4 , CD 5 , and CD 8 immunoprecipitates revealed that pp29 / 30 associates with these signaling receptor complexes but not with CD 18 , CD 27 , and CD 29 in human T lymphocytes . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Values of a coefficient reflecting individual reactivity of immunocompetent cells with surface antigens CD 5 , CD 4 , and CD 8 corresponding to type 2 reaction were found characteristic of children whatever their age or sex . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Flow cytometric analysis showed that BNY 2 cells were positive for CD 4 and CD 5 and were negative for CD 8 and RT 6 , indicating that these cells were phenotypically Th cells rather than cytotoxic T cells . mAbs against rat MHC class 2 Ags ( anti RT1 . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
For four cases of malignant lymphoma , T cell type , the pattern was again T cell phenotype with all of CD 2 , CD 5 , CD 7 and CD 4 . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
METHODS Phenotype analysis was performed on days 7 , 14 , 21 , 28 , 42 , 56 and 70 after arthritis induction using monoclonal antibodies to CD 5 , CD 4 and CD 8 subsets , and flow cytometry . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Human intrathymic precursors are characterized by mitogenic reaction on thymic hormone , lacking the cortical and medullar thymic membrane markers ( CD 3 , CD 4 and / or CD 8 ) and expressing of the common T cell CD 7 and CD 5 antigens . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
On both peripheral blood lymphocytes and thymocytes , PMA resulted in a rapid and transient down regulation of equine CD 4 expression , but had no such effect on the surface expression of equine CD 5 , CD 8 or major histocompatibility complex ( MHC ) class 1 and class 2 molecules . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
When we fixed cells with 50 % ice cold ethanol after staining cells with FITC conjugated antibodies , positive population ratio in these cells have been unchanged before and after fixing for CD 3 , CD 4 , CD 5 , CD 8 . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The cell phenotype was examined with immunofluorescence techniques using antibodies against SIg and monoclonal antibodies against CD 1 , CD 3 , CD 4 , CD 5 , CD 8 , CD 19 , and the kappa , and lambda light chains . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Encouraging results have been so far obtained with : a ) cyclosporine A , a somewhat more specific immunosuppressive agent ; b ) monoclonal antibodies against surface antigens ( CD 4 , CD 5 , CD 7 , CD 25 , CD 54 ) expressed on activated T cells ; c ) T cell vaccination ; and finally ( i . v . ) recombinant cytokines , their agonists or antagonists . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Re evaluation with additional immunohistochemical stainings in 11 patients showed a pleomorphic malignant infiltrate of histiocyte like cells of T cell origin , with a pattern of CD3+ ; CD 4 ; CD 5 + / ; CD7+ and CD 8 . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Trials have been conducted using antibodies against the surface markers CD 7 , CD 5 , CDw 52 and CD 4 . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Approximately 90 % of gamma / delta T cells from peripheral lymphoid organs have the same cell surface phenotype as thymus derived MHC class 1 restricted alpha / beta T cells , i . e . , they are CD 4 but express the CD 8 alpha / beta heterodimer together with CD 2 and CD 5 . ^^^ In contrast , gamma / delta T cells from the epithelium of the small intestine lack CD 2 , CD 4 , and CD 5 and express CD 8 alpha only . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The expression of CD 3 , CD 4 and CD 5 was not influenced by the superantigen . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
F4 / 80 and CR 3 macrophage antigens were detected with anti F4 / 80 and anti Mac 1 monoclonal antibodies ( mAb ) respectively , CD 4 and THY1 . 2 T lymphocyte antigens with GK1 . 5 and J1j mAbs respectively , B CD 5 lymphocytes were identified with LY1 . 2 mAb and Fc gamma RII / Fc gamma RIII were detected with 2 . 4G2 mAb . . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The neoplastic cells were negative for surface membrane CD 4 , CD 5 , and CD 8 . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The T cell composition of the thymus of 10 ray irradiated ( 3 . 5 Gy ) Wistar rat protected with WR 638 was analyzed by flow cytometry using monoclonal antibodies directed to the Thy 1 . 1 , CD 43 , CD 2 , CD 5 , CD 4 , CD 8 and class 1 and 2 MHC antigens . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Clusters of three or more antibodies were found that defined the canine equivalents of the CD 5 , CD 4 , CD 8 and Thy 1 antigens , and these could be used to label T cell subsets from the peripheral blood . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
In T lymphocytes , CD 2 forms part of a loosely associated membrane complex which includes the T cell receptor ( TcR ) for antigen , the CD 3 subunits , CD 4 or CD 8 , CD 5 and the protein tyrosine kinases p56lck and p59fyn . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
These were the antibodies against CD 2 , CD 4 , CD 5 , CD 8 , CD 14 , CD 18 , HLA DR , and the HLA ABC antigen . ^^^ Finally , the CD 2 , CD 4 , CD 5 and CD 8 antibodies reacted with leucocytes from monkey only . . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Con A treatment led to a significant increase in the percentage of cells bearing CD 8 , CD 6 , MHC Class 2 and J 5 , but it had no effect on the percentages of cells positive for the other T cell markers CD 5 , CD 4 , or CD 2 . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Absolute counts of CD 7 and CD 5 cells ( T cells ) were found reducing as was CD 4 cell ( T helpers ) level as the disease progressed . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
None of the other cytokines tested ( IL 1 alpha , IL 6 , TNF alpha , IFN alpha , IFN gamma ) supported growth of NK 92 cells which have the following characteristics : surface marker positive for CD 2 , CD 7 , CD11a , CD 28 , CD 45 , CD 54 , CD56bright ; surface marker negative for CD 1 , CD 3 , CD 4 , CD 5 , CD 8 , CD 10 , CD 14 , CD 16 , CD 19 , CD 20 , CD 23 , CD 34 , HLA DR . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Total melanoma gangliosides in micelles inhibited proliferation of peripheral blood mononuclear cells stimulated by various mitogens , modulated lymphocyte surface molecules CD 2 , CD 3 , CD 4 , CD 5 and CD 8 and inhibited the production of interleukin 1 beta ( IL 1 beta ) , tumor necrosis factor alpha ( TNF alpha ) and IL 6 by stimulated adherent cells . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
These results indicate that ( a ) the mAb KH 8 , NA 6 , PD 4 and TH 8 identify the avian homologue of the mammalian CD 4 molecule , ( b ) the mAb OC 2 detects the avian CD 2 antigen , and ( c ) the mAb OC 5 recognizes the putative avian CD 5 homologue . . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
AG F cell line demonstrated an unusual phenotype , lacking surface CD 2 and CD 3 , but expressing high levels of CD 4 , CD 5 , CD 7 , CD 29 , and CD45RO . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
We focused on immunophenotypic differences between the two types of lesions with respect to the T cell markers CD 2 , CD 3 , CD 4 , CD 5 and CD 8 . ^^^ Three of the patients studied ( 20 % ) showed a difference in immunophenotype between plaques and tumours , with an additional loss of one of the T cell markers in the tumours ( respectively , CD 5 , CD 2 and CD 4 ) . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Monoclonal antibodies against activation antigens , including CD 4 , CD 5 , CD 25 ( interleukin 2 receptor ) , CD 52 , and adhesion molecules , have been investigated in animal studies and open trials in humans . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Transfectants expressing CD 4 , CD 5 , CD 8 , CD 25 , CD 44 , two different WC 1 gene products and a transfectant expressing an unknown gene product were isolated using these techniques . ^^^ The results confirm the fine specificity of mAbs for two alleles of CD 4 and CD 5 ; they also subdivide mAbs recognizing CD 8 into two groups based on their specificity for the CD 8 alpha chain or a combination of both alpha and beta chains . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The medium and large lymphoid cells were positive for CD 20 , CD 22 and HLA DR and negative for CD 3 , CD 4 , CD 5 , CD 8 , CD 43 , and kappa and lambda light chain . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The first case expressed natural killer ( NK ) cell , some T cell ( CD 2 , CD 5 , CD 8 ) , and HLA DR antigens , but was negative for other T cell ( CD 3 , CD 4 , CD 7 ) , T cell receptor ( TCR ) , B cell , and myeloid antigens . ^^^ The second case expressed NK cell , some T cell ( CD 3 , CD 7 , CD 8 ) , and TCR antigens , but was negative for other T cell ( CD 4 , CD 5 ) , B cell , myeloid , and HLA DR antigens . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The lymphoid component showed a mature T cell immunophenotype ( positive for CD 2 , CD 3 , CD 5 , CD 7 , CD 4 , CD 8 ) . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The neoplastic cells expressed the T cell receptor ( TCR ) delta chain detected by TCR delta 1 and delta TCS 1 , CD 3 , CD 30 , CD45RO , and epithelial membrane antigen , but not the TCR beta chain detected by beta F 1 , CD1a , CD 2 , CD 4 , CD 5 , CD 7 , CD 8 , CD 25 , HLA DR , and terminal deoxynucleotidyl transferase . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Previously we have succeeded in generating monoclonal antibodies ( mAbs ) against rabbit CD 4 , CD 5 and CD11a antigens . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Multiparameter flow cytometry was used to analyze the array of immature phenotypes present in the SCID thymus at steady state , as defined by the markers CD 4 , CD 5 , Sca 1 , NK1 . 1 , CD 44 , heat stable antigen ( HSA ) , and IL 2R alpha . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Six cases displayed a CD 3 , TCR alpha beta , TCR gamma delta , CD2+ , CD7+ , CD 5 , CD 4 , CD 8 , CD56+ phenotype , suggesting that these tumors may be peripheral T cell lymphomas ( PTCL ) with extensive loss of T cell antigens and expression of the NK cell ( CD 56 ) antigen or , alternatively , NK cell neoplasias . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Protein tyrosine kinases have been implicated in signal transduction in T lymphocytes after stimulation of many cell surface molecules , including the T cell antigen receptor , CD 4 , CD 8 , CD 2 , CD 5 , and CD 28 . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Blocking experiments with monoclonal antibodies ( MoAbs ) against CD 4 , CD 21 ( complement receptor 2 [ CR 2 ] ) , CD 35 ( CR 1 ) , CD 19 , and CD 5 surface molecules indicated that infection of B cells involves CD 4 , CD 21 , and CD 35 antigens . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
According to the results obtained , the second level of investigation assessed the positivity for intra cytoplasmic ( Cy ) Ig , CD1a , CD 2 , CD 3 , CD 4 , CD 5 , CD 8 and CD 20 . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
These correlated with normal frequency of CD 4 , CD 5 , CD 8 phenotype subsets and B cells in recipient lymphoid organs , as shown by flow microfluorimetry . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The inability of LOA to present superantigen is not due to a structural difference in MHC 2 molecules between LOA and the splenic APC or to differential expression of major accessory / adhesion molecules , including CD 2 , CD 5 , CD 4 and CD 44 , on LOA . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
This report describes the immunocytochemical detection and distribution of different canine leucocytes antigens ( Thy 1 , CD 5 , CD 4 , CD 8 , MHC 2 and B cell antigen ) by means of monoclonal antibodies ( mAbs ) in frozen tissue sections of lymphoid organs of the dog . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
We have shown that when a whole blood method of cell staining is used for flow cytometric analysis of sheep lymphocytes ( i . e . red cell lysis after addition of antibody ) , staining may be delayed for up to 48 h after blood collection without significant effect on expression of CD 4 , CD 5 , CD 8 or B cell markers . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Indirect immunofluorescence , generated by monoclonal antibodies ( mAb ) specific for canine CD 5 , CD 4 , CD 8 , CD45pan , CD45RA , MHCII and THY 1 , was detected by flow cytometry . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
In this study the expression of ' classically ' considered lymphoid associated antigens ( CD 2 , CD 3 , CD 4 , CD 5 , CD 7 , CD 8 , CD 10 , CD 19 , CD 20 , and CD 22 ) was explored both in peripheral blood ( PB ) and bone marrow ( BM ) mast cells ( MC ) in a case of systemic mast cell disease ( SMCD ) by means of using multiple stainings and a direct immunofluorescence technique . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The percentage of T cells ( CD 5 ) , B cells and the ratio of CD 4 cells / CD 8 cells were smaller in the FK group . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Most of the infiltrated lymphocytes were positive for CD 2 , CD 3 , CD 4 and CD 5 . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Lymphocytes in both bronchoalveolar lavage and peripheral blood were labelled with monoclonal antibodies against the main T lymphocyte subsets ( CD 4 , CD 8 , CD 5 and gamma delta TCR ) in order to perform flow cytometric studies . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NKL cells express CD 2 , CD 6 , CD11a , CD 26 , CD 27 , CD 29 , CD 38 , CD 43 , CD 58 , CD 81 , CD 94 , CD 95 , class 2 MHC , and the C1 . 7 . 1 antigen , but do not express detectable levels of CD 3 , CD 4 , CD 5 , CD 8 , CD 14 , CD 19 , CD 20 , CD 28 , alpha / beta or gamma / delta T cell receptors on the cell surface . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Typical mature rat DCs were morphologically similar to their mouse and human counterparts and expressed major histocompatibility complex ( MHC ) class 2 ( common part determinant of Ia ) , OX 62 ( integrin molecule ) , OX 7 ( CD 90 ) , ICAM 1 ( CD 54 ) , and CTLA 4 counterreceptor , but were negative for OX 8 ( CD 8 ) , OX 19 ( CD 5 ) , W3 / 25 ( CD 4 ) , and ED 2 , a rat macrophage marker . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Immunohistochemical stains for CD 5 and CD 4 T lymphocyte markers were performed on lesion sections 4 , 10 , 15 , and 21 days from infection . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
IVIG has been shown also to interact with surface molecules of T cells that are essential to immune regulation , such as the alpha beta TCR , CD 5 , CD 4 , non polymorphic determinants of MHC class 1 molecules and adhesion molecules of T and B cells . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Using a monoclonal antibody to murine CD 38 , we showed that a population of adult bone marrow cells that expressed the markers Sca 1 and c kit but lacked the lineage markers Mac 1 , GR 1 , B 220 , IgM , CD 3 , CD 4 , CD 8 and CD 5 could be subdivided by the expression of CD 38 . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Immunophenotyping of lymphoma revealed CD45++ , c kit dim+ , terminal deoxynucleotidyl transferase ( TdT ) < + , CD38++ , CD34+ < ++ , CD33+ < , CD13dim+approximately+ , HLA DR+ , CD7+ , cytoplasmic CD 3 ( cCD 3 ) + , surface CD 3 ( sCD 3 ) , CD2dim+ , CD56+ , CD 16 , CD11b+ , CD 57 , CD1a , CD 5 , TCR alpha beta , TCR gamma delta , CD 4 , CD 8 , CD 28 , CD 10 , CD 19 , CD 20 , CD 22 , surface immunoglobulins , and CD 14 . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The proportion CD 4 , CD 5 , and CD 8 positive lymphocytes in BALF was not affected by administration of nHuIFN alpha . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Immunocytochemical analyses of tissue sections of ascending aortas performed with monoclonal antibodies to T and B lymphocytes and macrophages revealed that T lymphocytes immunoreactive for Thy 1 . 2 , CD 5 , CD 4 , and CD 8 were observed in lesions from both strains , but no B lymphocytes were detected . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Although they usually express a restricted number of T cell related antigens , namely , CD 2 , CD 43 , and CD45RO , other pan T or subset T lineage antigens , such as CD 3 ( membrane ) , CD 5 , CD 4 , CD 8 , and CD 7 , are frequently absent . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Immunohistochemistry was performed with antibodies against the macrophage markers ED 1 , ED 2 , and OX 42 , the MHC class 2 antigen marker OX 6 , the T lymphocyte markers CD 4 , CD 5 , and CD 8 , and other markers , such as alpha smooth muscle actin , proliferating cell nuclear antigen , and von Willebrand factor . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
In one case , frozen section immunohistochemistry demonstrated the absence of expression of CD 5 , CD 4 , or CD 8 by the T cell lymphoma . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Bronchoalveolar lavage fluid ( BALF ) and peripheral blood were obtained from each of 17 adult Arabian mares and absolute numbers and relative lymphocyte proportions were determined for total T lymphocytes , using CD 2 as a marker , CD 4 + T lymphocytes , CD 8 + T lymphocytes , CD 5 + lymphocytes , and sIgM + B lymphocytes . ^^^ The mean percentages of CD 4 + T lymphocytes ( 58 + / 13 % in BALF ; 62 + / 8 % in peripheral blood ) and CD 5 + lymphocytes ( 78 + / 11 % in BALF ; 71 + / 7 % in peripheral blood ) , a population composed primarily of T lymphocytes but also including a subset of sIgM + B lymphocytes , were not significantly different between the two compartments . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Leucocyte counts and lymphocyte phenotypic analyses were performed using either differential staining or an indirect immunofluorescence assay with monoclonal antibodies specific for equine ( Eq ) CD 4 , CD 5 , CD 8 and B lymphocytes . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
For each sample phycoerythrin ( PE ) conjugated CD 2 , CD 4 , CD 5 , CD 8 , and CD 56 monoclonal antibodies were combined with Cy 5 R phycoerythrin ( TC ) conjugated CD 3 and fluorescein isothiocyanate ( FITC ) conjugated CD 7 ; CD 2 and CD 7 PE were also combined with CD 3 TC and CD 4 FITC . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Lymphocyte subsets ( CD 5 , CD 3 , HLA DR , CD 4 , CD 8 , CD 19 , CD3 / CD16+56 , CD 57 , CD 18 , CD16 / CD122 ) all increased after the run , decreased to normal or subnormal levels after 2 h , and returned to normal after 24 h ( absolute numbers ) . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
They neo expressed CD1a , CD1b , CD1c , CD 80 , and CD 5 ; they massively up regulated CD 40 ( 109 fold ) and HLA DQ and DP ( 125 and 87 fold ) ; and significantly ( > 5 fold ) up regulated HLA DR , CD 4 , CD11b , CD11c , CD 43 , CD 45 , CD45R0 , CD 54 , CD 58 , and CD 59 . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Two types of large complexes containing protein tyrosine kinases were observed : the first one contained CD 3 and the transmembrane proteins CD 2 , CD 4 , CD 5 , CD 6 , CD 7 , CD 8 , CD11a , CD 38 , CD 43 , CD 45 , CD 71 , CD 98 and CD 99 and the other contained mainly the GPI anchored proteins CD 48 , CD 55 , CD 59 and CDw 108 as well as a fraction of CD 4 and CD 8 . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
This inhibitory effect is not due simply to nonspecific perturbation or Fc binding , since F ( ab ) fragments of anti CD 4 are as potent as the intact antibodies , whereas antibodies to class 1 molecules or T cell CD 5 have no effect . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The mononuclear cells stained positively for Pan T , CD 2 , CD 3 , CD 4 , CD 5 , CD 25 , and DNA from the cells showed HTLV 1 provirus monoclonal integration . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Frozen sections were stained with monoclonal antibodies directed against IL 7R , CD 25 , CD 30 and T antigens ( CD 3 , CD 2 , CD 5 , CD 7 , CD 4 , CD 8 ) , using the alkaline phosphatase antialkaline phosphatase technique . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
While the C kit+ population at this stage is more homogeneous than at any other stage of fetal thymus development , there are still markers ( B 220 , CD 5 , Tsa , Mac 1 , CD 4 , and Sca 1 ) that can split this population into other subsets . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Receptor mediated activation of LCK does not in itself lead to activation of this Tec kinase since induction of LCK by ligation of CD 4 or CD 5 did not result in activation of EMT . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The peripheral blood lymphocytes were analyzed using a double colored flow cytometry and adequate monoclonal antibodies to CD 2 , CD 3 , CD 4 , CD 5 , CD 8 , CD11b , CD 16 , CD 19 , and HLA DR receptors . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The percentages of CD 19 , CD 5 , CD 4 and CD 8 cells and of IL 2R were determined when rejection was present . ^^^ In both B and C groups , CD 5 and CD 4 cells decreased ( P < 0 . 005 ) and CD 8 cells increased ( P < 0 . 001 ) . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
In addition , the phenotype of the cells was measured using flow cytometry with antibodies against CD 4 , CD 8 , CD 5 , MHC class 2 , CD 25 , CD 14 and CD 19 . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
CD 2 , CD 5 , CD 10 , and CD 19 were expressed in a similar fashion among the different FAB groups , whereas CD 4 expression was significantly more frequent in AML M 0 , AML M 4 , and AML M 5 ( P = . 014 ) . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Pretreatment levels of natural killer ( NK ) activity , CD 3 , CD 4 , CD 5 , CD 8 , CD 16 , CD 19 , CD 56 , DR , and the CD4 / CD8 ratio were evaluated for any relationship with survival . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Splenic T lymphocytes were less impaired and were more responsive to rhIGF 1 treatment ; there was a maximum loss of 71 % of T cells in Restricted , alcohol fed rats . rhIGF 1 treatment completely restored splenic cellularity , as well as each of the T lymphocytes studied : CD 5 , CD 4 , and CD 8 . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Fostering also down regulated CD 5 antigen expression in E compared with C offspring and up regulated CD 4 antigen expression in C offspring compared with their nonfostered counterparts . ^^^ However , after fostering , E females had higher CD45RA and CD 5 antigen expression compared with PF and C females , whereas E males had increased CD 4 antigen expression and C males had decreased CD 5 antigen expression compared with their nonfostered counterparts . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
METHODS : Conjunctival biopsy specimens obtained 48 hours after a 2 mm biopsy of the epibulbar conjunctiva in 26 Turkish patients with inactive ocular Behet disease and 9 Turkish patients with inactive idiopathic uveitis were studied by immunoperoxidase using a panel of monoclonal antibodies : anti CD 1 , CD 3 , CD 4 , CD 5 , CD 14 , CD 22 , CD 25 , and CD 67 , HLA DR , E selectin , intercellular adhesion molecule 1 ( ICAM 1 ) , and vascular cell adhesion molecule 1 ( VCAM 1 ) . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The ration of CD 3 , CD 4 , CD 8 , CD 19 , CD 5 , CD 25 HLA DR cells in full blood was assessed by the monoclonal antibody technique of direct immunofluorescence , using evaluation by means of a flow cytometer . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Induction of HIV 1 resistance was specific for CD 28 costimulation , in that a variety of other accessory receptors , such as CD 2 , CD 4 , CD 5 , and MHC class 1 , failed to confer the antiviral resistance . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
CD 19 , CD 20 , CD 5 , CD 2 , CD 4 , CD 8 surface markers and amplification of the Ig heavy chain CDR 3 locus were used for immunophenotypic and genotypic analysis , respectively . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Extravascular fluids , suspension of single cells and BAL are preferred materials for detection and classification of non Hodgkin lymphomas ( MOAb for immunophenotyping of lymphocytes : CD 14 , CD 45 , CD 3 , CD 19 , CD 4 , CD 8 , CD16 / 56 , HLA DR , CD 38 , CD 25 , CD 23 , CD 5 , CDl1c , CD 30 , light chain immunoglobulins ) . . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
T cell receptors ( TCR ) , surface CD 3 , CD 4 , CD 5 and CD 8 were not expressed . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
BAL cells were harvested and stained with antibodies to the equine homologues of CD 5 , CD 4 , CD 8 , CD 44 , MHC 1 , MHC 2 and to equine IgG . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Immunophenotyping of the circulating lymphocytes revealed mature T cells ( CD 3 , CD 5 , CD 7 positive ) with normal proportions of both CD 4 ( 55 % ) and CD 8 ( 38 % ) positive cells . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Immunophenotyping showed that most peripheral blood mononuclear cells were negative with B lymphoid , myeloid , and stem cell associated markers and were also negative with most T lymphoid markers ( CD 2 , CD 4 , membrane / cytoplasmic CD 3 , CD 5 and CD 8 ) . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The immunophenotype of the tumour cells was CD2+ , CD 3 , CD 4 , CD 5 , CD7+ , CD 8 , CD45RO+ , CD45RA , CD56+ , CD 57 . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The phenotype of intraepithelial and lamina propria lymphocytes was assessed by FACS analysis using markers for CD 3 , TCR alpha beta , TCR gamma delta , CD 4 , CD 8 alpha , CD 8 beta , CD 5 , CD 18 , CD 54 , and CD49d . ^^^ The percentage of intraepithelial lymphocytes expressing TCR alpha beta , CD 4 , CD 5 , and CD 54 , as well as the levels of expression of these antigens , increased after spermine treatment on day 12 , similarly to natural maturation . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
RESULTS : Lipocortin 1 fluorescence was readily detected in control rat peripheral blood cells labeled with OX 1 ( pan leukocyte ) , OX 19 ( CD 5 ) , W3 / 25 ( CD 4 ) , and OX 8 ( CD 8 ) . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Constant detection of CD 2 , CD 3 , CD 4 , and CD 5 in fixed and paraffin embedded tissue using the peroxidase mediated deposition of biotin tyramide . ^^^ Using this optimized ImmunoMax method , we were able to detect CD 2 , CD 3 , CD 4 , and CD 5 with conventional monoclonal antibodies in formalin fixed , paraffin embedded tissue specimens of various lymphoid tissues . . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The lymphoid cells were positive for mature B cell antigens and the phenotype was : CD 5 , CD 10 , CD19+ , 20+ , CD22+ , IgG+ , IgA , IgM , kappa , lambda+ , CD 1 , CD 2 , CD 3 , CD 4 , CD 7 , CD 8 . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Within the lymphocyte population in thrombocytapheresis products the distribution of CD 3 , CD 19 , CD 4 , CD 8 , CD 57 , CD 5 , HLA DR and gamma / delta T cells did not differ significantly from the corresponding distribution in the peripheral blood of the donors . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
PBL subsets were analyzed by flow cytometry with the use of monoclonal antibodies against CD 2 , CD 3 , CD 4 , CD 5 , CD 8 , CD 16 , CD 20 , CD45RA , CD 56 , CD 57 and HLA DR . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The CL 1 cells were positive for CD 45 and MHC class 2 and negative for CD 4 , CD 5 , CD 8 , Thy 1 and B cell specific antigen and surface immunoglobulin . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Kidneys were examined morphologically and immunohistologically using monoclonal antibodies ( mAbs ) against macrophages ( ED 1 ) , T cells and their subsets ( CD 5 , CD 4 , CD 8 ) , MHC class 2 expression ( OX 3 ) and adhesion molecules ( ICAM 1 and LFA 1alpha ) . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
These cells express high levels of Sca 1 , H 2K and CD 38 and low levels of Thy 1 . 1 , but do not express CD 34 nor any of the lineage markers including CD 3 , CD 4 , CD 5 , CD 8 NK1 . 1 , 1 A , B 220 , Ig ( MGA ) , CD 40 , kappa , Mac 1 , Gr 1 or Ter 119 . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
All glycosylphospha tidylinositol ( GPI ) anchored proteins ( CD 14 , CD16B , CD 48 , CD 59 , CD 87 and GPI anchored versions of CD 2 and CD 25 ) and protein tyrosine kinase ( PTK ) Lck but not transmembrane proteins ( CD 2 , CD 4 , CD 5 , CD 6 , CD 8 ) and PTK ZAP 70 were in part localized in buoyant , lipid rich , detergent resistant membrane GPI microdomains of the COS cells . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
In whole blood samples , subpopulations of peripheral lymphocytes were analyzed by flow cytometry using FITC or PE labeled monoclonal antibodies against rat CD 5 , CD 4 , and CD 8 . ^^^ Flow cytometric analysis of peripheral blood lymphocytes revealed that , except for a transient increase in CD 4 positive T lymphocytes in OVX rats relative to SHAM animals at 1 week post surgery , the number of CD 5 , CD 4 , or CD 8 positive lymphocytes or the mean fluorescence per cell for these antigens in OVX rats remained unchanged throughout the study . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Immunohistochemical studies of lymphoma cells showed a T cell gamma delta phenotype ( CD3+ , CD2+ , TCR delta 1+ , 5 delta 2+ and beta F 1 ) without expression of CD 4 , CD 8 , CD 5 , or HML 1 . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Some immunophenotypes correlated with FAB type , including increased frequency of CD 2 expression in AML M 3 ; lack of CD 4 , CD11c , CD 36 , CD 117 , and HLA DR expression in AML M 3 ; increased frequency of CD 20 and CD 36 expression and lack of CD 34 expression in AML M 5 ; increased frequency of CD 5 expression in AML M5a ; and increased frequency of CD 14 expression in AML M5b , when compared with all other AMLs ( P < . 05 ) . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
IEL and LPL were isolated from the small intestine and the phenotype was assessed by FACS analyses , using antibodies for detection of T cell markers CD 3 , TCR alpha beta , TCR gamma delta , CD 4 , CD 8 alpha , CD 8 beta , CD 5 , CD 18 , CD 54 , and CD49d . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Newly confirmed mAb assignments included : two CD 2 ; one CD 4 ; two CD 5 ; one wCD 6 ; and one wCD 25 . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
However , analysis of cell surface marker expression by FACS revealed a surface phenotype similar to that of pre B cells ( MHC I+ , MHC II+ , B7 . 2+ , sIgM , sIgG , kappa , B 220 , CD 5 , Thy1 . 2 , TcR , CD 3 , CD 4 , CD 8 , Mac 1 , 33D1 ) . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
A large proportion of the CD19+ cells also expressed CD 4 , CD 5 , and CD 8 antigens . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Co labelling with CD 4 , CD 8 , and CD 5 indicated an increase in the percentage of GM 1 mutant cat thymocytes at this age which were CD5high , suggesting the presence of more mature cells . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
At fluorescence activated cell sorting ( FACS ) analysis of the peripheral blood , the lymphocytes were positive for CD 3 , CD 4 , CD 5 , CD 29 , CD45RA , CD 57 , and TCR alpha / beta and negative for CD 7 , CD 8 , CD 16 , CD 56 , CD 19 , CD 22 , and TCR gamma / delta . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Monoclonal antibodies were used against CD 3 , CD 4 , CD 5 , CD 8 , CD 10 , CD 19 , CD 22 , HLA DR , and TdT . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
METHODS : Immunohistochemical studies with antibodies to CD 4 , CD 5 , CD 7 , and CD 8 and TCR gamma gene rearrangement analysis with a polymerase chain reaction were performed on fresh frozen material of patients with `` classic ' ' histology of MF , `` inconclusive ' ' histology , and benign inflammatory dermatoses . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
With the advent of new monoclonal antibodies developed against T cell antigens , including CD 3 , CD 4 , CD 5 , and CD 8 , it is now possible to immunophenotype T cell subpopulations in paraffin embedded tissues . ^^^ To investigate the potential use of these antibodies for the evaluation of cutaneous lesions , 35 specimens ( 34 skin and 1 lymph node ) from 29 patients with MF were retrospectively reviewed and immunophenotyped in paraffin sections with antibodies to CD 3 ( T cell CD 3 ) , CD 4 ( NCL CD 4 1F6 ) , CD 5 ( NCL CD 5 4C7 ) , CD 8 ( CD8 / 144B ) , and CD 20 ( L 26 ) . ^^^ In 32 cases , the neoplastic cells expressed CD 3 , CD 4 , and CD 5 consistent with a T helper / inducer phenotype . ^^^ We concluded , therefore , that the immunophenotypic analysis of T cell subpopulations using monoclonal antibodies of CD 3 , CD 4 , CD 5 , and CD 8 was useful for histologic evaluation and confirmation of MF lesions in paraffin embedded tissue . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The whole extracellular region of CD 5 , expressed as a chimaera with rat CD 4 domains 3 and 4 ( cCD5d1 3 CD4d3+4 ) , was studied by electron microscopy and carbohydrate analysis to gain an overview of the structure of the extracellular portion of intact CD 5 . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The results demonstrate that low level expression of CD 5 on CD 4 ( ) CD 8 ( ) ( double negative , DN ) thymocytes is independent of TCR gene rearrangement ; however , induction of CD 5 surface expression on DN thymocytes requires engagement of the pre TCR and is dependent upon the activity of p 56 ( lck ) . ^^^ At the CD 4 ( + ) CD 8 ( + ) ( double positive , DP ) stage , intermediate CD 5 levels are maintained by low affinity TCR major histocompatibility complex ( MHC ) interactions , and CD 5 surface expression is proportional to both the surface level and signaling capacity of the TCR . ^^^ High level expression of CD 5 on DP and CD 4 ( + ) or CD 8 ( + ) ( single positive , SP ) thymocytes is induced by engagement of the alpha / beta TCR by ( positively or negatively ) selecting ligands . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
No cases were interpreted as T lineage , but the T cell antigens CD 3 , CD 4 , CD 5 , and CD 7 were expressed in 5 . 0 , 40 . 0 , 5 . 3 . and 30 . 0 % of all cases , respectively . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The vast majority of DPP 4 positive T ALL cases expressed CD 4 , CD 8 , CD 7 , CD 5 , CD 2 along with CD 71 and CD 38 antigens , but the cells were surface membrane CD 3 antigen negative . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The ITLs expressed cytoplasmic CD 3 and antigens associated with cytolytic function ( TIA 1 , granzyme B ) , but not CD 4 and CD 5 . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Nonlineage expression of markers ( CD 1 , CD 2 , CD 4 , CD 5 , CD 7 , and CD 56 ) was nonspecific as to AML subtype . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Recombinant soluble forms of six leukocyte antigens belonging to the Ly 6 ( CD 59 ) , scavenger receptor ( CD 5 ) , and immunoglobulin ( CD 2 , CD 48 , CD 4 , and Thy 1 ) superfamilies were expressed in the same Chinese hamster ovary cell line , thus providing an opportunity to examine the extent to which N linked oligosaccharide processing might vary in a superfamily , domain , or protein dependent manner in a given cell . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The lymphoma expressed CD 2 , CD 3 , CD 7 , CD 8 and CD 56 , and the gammadelta T cell receptor and did not express CD 5 , CD 4 and the alphabeta T cell receptor . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
A panel of specific antibodies against CD 3 , CD 4 , CD 5 , CD 8 , MHC 1 and 2 was used in single and two colour flow cytometry to define T cell subpopulations in bronchoalveolar lavage fluid of horses affected with chronic obstructive pulmonary disease and of healthy controls . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Lymphocyte measurements included total lymphocyte counts ; T cell ( CD 3 , CD 4 , CD 5 , and CD 8 ) , B cell ( CD 20 ) , and NK cell ( CD 16 and CD 56 ) subsets ; and expression of the activation antigen CD 25 on CD 3 T cells . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Examination of leukocyte cell surface antigens expressed by splenocytes revealed no statistically significant changes in the level of the T lymphoid antigens Thy 1 , CD 5 , CD 4 , CD 8 and CD 3 , the macrophage antigen Mac 1 , and the adhesion molecules LFA 1alpha , LFA 1beta and L Selectin , following GM CSF immunostimulation . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
A small fraction of rat 13 day old fetal liver ( r13FL ) cells , which weakly expressed the leukocyte common antigen CD 45 , constituted a homogeneous Thy 1 ( hi ) , CD 71 ( ) , CD 44 ( + ) , MHC class I+ , CD 43 ( + ) cell subpopulation negative for CD45RC , CD 3 , TCRalphabeta , TCRgammadelta , CD 2 , CD 5 , CD 4 , CD 8 , CD 25 , CD 28 , NKR P1a and sIg . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
FPM 1 originated from rat thymocytes cocultured with a human HTLV 1 producer , MT 2 cells , and expressed rat CD 4 , CD 5 , CD 25 , and HTLV 1 Tax . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
They did not express CD 3 , CD 4 , CD 5 , CD 10 , CD11b , CD 13 , CD 25 , CD 56 , CD 14 , CD 33 , or CD 64 . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
In three patients with identified clones ( Vbeta 3 . 1 , 5 . 3 and 6 . 7 ) , double staining revealed positivity for CD 2 , CD 3 , CD 4 , CD 5 , CD45RO and CD 7 in a significant proportion ( at least 35 % ) . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The blasts were strongly positive for both CD 7 and CD 56 but negative for other T lineage associated antigens , including CD 1 , CD 2 , surface membrane CD 3 , cytoplasmic CD3c ( 2 / 2 ) , CD 4 , CD 5 and CD 8 . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Phenotypic analysis showed CD2+ , CD3 / Leu4 , cytoplasmic CD3epsilon+ , CD 4 , CD 5 , CD7+ , CD 8 , CD 16 , CD38+ , CD56+ , CD 57 , TdT , granzyme B , and TIA1+ phenotype . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Although normal alveolar macrophages ( AMs ) did not bear or bore low levels of costimulatory molecules , AMs from sarcoid patients with CD 4 T cell alveolitis upmodulated CD 80 , CD 86 , and CD 72 and expressed high levels of interleukin ( IL ) 15 ; lymphocytes accounting for T cell alveolitis expressed Th 1 type cytokines [ interferon ( IFN ) gamma and / or IL 2 ] and bore high levels of CD 5 and CD 28 but not of CD 152 molecules . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
A panel of monoclonal antibodies was used : CD 5 , CD 4 , CD 8 , CD 25 , and CD45RA . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Her bone marrow was normocellular with an excess of blasts ( 89 . 1 % , peroxidase stain ( ) , PAS stain ( ) ) that displayed a positive immunophenotype for CD 2 , CD 4 , CD 5 , CD 7 , CD 34 , CD 38 , and CD 71 . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
An influence of CD 5 on the selection of CD 4 lineage T cells . ^^^ Combining CD 5 null , MHC deficient and lineage specific reporter animals , we have investigated the influence of CD 5 on positive selection and the choice of CD 4 versus CD 8 lineage commitment on broad populations of thymocytes . ^^^ Our results indicate that CD 5 negatively regulates the differentiation of CD 4 committed cells in suboptimal conditions , thus perhaps serving to tighten the correlation between restriction of the TCR and lineage choice . . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Flow cytometry ( FCM ) analyses of Thy 1 . 1+ IEL showed that Thy 1 . 1 was co expressed with CD 3 , CD 4 , CD 5 , CD 8 , TCR alpha beta and TCR gamma delta T cell markers . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Biopsy specimens of the small intestine disclosed extensive and diffuse infiltration of the lamina propria by pleomorphic small T lymphocytes , which were positive for CD 3 , CD 4 , CD 5 , and the beta chain of T cell receptor in all three cases studied and negative for CD 103 in all three cases studied . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Immunophenotyping of the peripheral blood T cells revealed evidence for a clonal expansion of highly activated CD 4 ( + ) T cells with reduced CD 2 and CD 5 surface expression . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Quantitative immunophenotyping with computer assisted imaging was performed using immunohistochemical stains of anti CD 3 , CD 4 , CD 5 , CD 7 , CD 8 , CD 20 , CD 30 , CD 56 , CD 68 , Bcl 2 , p 53 , and proliferating cell nuclear antigen ( PCNA ) . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
In addition , this association was enhanced following independent ligation of the CD 2 , CD 4 , or CD 28 costimulatory molecules , but not of CD 5 or CD 6 surface receptors , correlating to the induced tyrosine phosphorylation of Emt . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Negative regulation of CD 4 lineage development and responses by CD 5 . ^^^ Here we show that the development and responses of CD 4 lineage T cells are regulated by the function of CD 5 . ^^^ Finally , CD 5 deficiency partially suppresses the block of CD 4 lineage development in CD 4 deficient mice . ^^^ Taken together , the data support a general role for CD 5 as a negative regulator of Ag receptor signaling in the development and immune responses of CD 4 lineage T cells . . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The majority of normal gammadelta T cells are negative for surface CD 4 and CD 8 and a subpopulation does not express CD 5 , two immunophenotypic findings strongly suggestive of neoplasia in alpha beta T cells . ^^^ In this study , up to 22 % of PBLs were CD 4 and CD 8 negative gammadelta T cells and up to 33 % PBLs were CD 5 negative gammadelta T cells . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Immunoprecipitation of T cell lysates with anti CD 9 mAb followed by immunoblotting with mAb against various T cell molecules showed the association of CD 9 with CD 3 , CD 4 , CD 5 , CD 2 , CD 29 and CD 44 . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Histologic sections of a cervical lymph node demonstrated a marked paracortical proliferation of occasional small and intermediate sized lymphocytes and numerous large immunoblasts , the majority of which displayed a CD 3 ( + ) , CD 43 ( + ) , CD45RO ( ) ( OPD 4 , UCHL 1 ) CD 4 ( ) , CD 8 ( ) phenotype on paraffin sections , and which had a CD 2 ( + ) , CD 3 ( + ) , CD 5 ( + ) , CD 56 ( ) , Tdelta 1 ( ) , [ CD 4 ( ) , CD 8 ( ) ] double negative profile on flow cytometric analysis . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
In contrast , the CD123strong+ / CD33dim+ DC showed a stronger reactivity for the CD 4 and CD45RA molecules , whereas they did not express the CD 58 , CD 5 , CD11c and CD 13 antigens . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The patient had marked splenomegaly , generalized lymphadenopathy and marked proliferation of abnormal lymphocytes in the peripheral blood with an irregular nucleus , deeply basophilic cytoplasm and a single prominent nucleolus , which were positive for CD 2 , CD 3 , CD 5 , CD 7 , CD 4 and CD 8 . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
CD 5 costimulation up regulates the signaling to extracellular signal regulated kinase activation in CD4+CD8+ thymocytes and supports their differentiation to the CD 4 lineage . ^^^ When CD 3 and CD 5 on CD4+CD8+ thymocytes in culture were coligated , they lost CD 8 , down regulated CD 4 expression , and induced CD 69 expression , yielding a CD4+ ( dull ) CD 8 CD69+ population . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
K 2 MDS cells are positive for the expression of CD 4 , CD 5 , CD 13 , CD 25 , CD 71 , CD 95 , HLA DR and cytoplasmic CD 3 . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Flow cytometric analysis revealed that the expression of CD 4 and CD 8 on T cells was decreased in Donryu rats , though the expression of other T cell markers such as CD 2 , CD 3 and CD 5 was not different . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The variable CD 4 and / or CD 8 antigen expression , frequent CD 5 and CD 7 positivity and absence of surface membrane CD 3 antigen were the characteristic immunophenotypic features of CD26 / DPP 4 positive T lymphoblasts . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
CD 3 , CD 4 , CD 5 , and CD 8 antigen expression of T cells and IgG expression of B cells and canine distemper virus ( CDV ) antigen distribution were immunohistochemically examined in lymphoid tissues ( lymph node , spleen , thymus , and tonsil ) of control dogs and animals with spontaneous canine distemper . ^^^ In group 1 dogs , a marked loss of CD 3 , CD 4 , CD 5 , CD 8 , and IgG expression was noticed , hereby loss of CD4+ cells was more prominent than depletion of CD8+ cells . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
This paper presents a standardized gating protocol , and average values and ranges observed for normal canine and feline blood lymphocytes using commercially available antibodies to cell surface markers for CD 5 , CD 3 , CD 4 , CD 8 , MHC 2 , and B lymphocytes . ^^^ The averages for these markers on gated lymphocytes were as follows : Canine CD 5 83 . 3 % , Canine CD 4 45 . 0 % , Canine CD 8 28 . 8 % , Canine MHC 2 98 . 0 % , Canine B Cell 12 . 9 % , Canine CD4 / CD8 ratio 1 . 87 , Feline T lymphocytes 77 . 3 % , Feline CD 4 44 . 5 % , Feline CD 8 25 . 7 % , Feline B Cell 24 . 1 % , Feline CD4 / CD8 Ratio 1 . 75 . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Surface marker analysis of lymph node cells was positive for CD 2 , CD 3 , CD 4 , CD 5 , CD 56 , and HLA DR . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Immunologic characterization of these cells revealed positivity for CD 3 , CD 5 , CD45RO , CD 56 , and T cell intracellular antigen ( TIA ) , and negativity for CD 2 , CD 3 , CD 4 , CD 8 , CD 57 , CD 34 , and terminal deoxynucleotidyl transferase ( TdT ) . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Transformed and nontransformed cells expressing MHC class 1 , CD 5 , CD 3 , CD 4 , CD 6 , CD 7 , CD 34 , CD 45 , MHC class 2 , Fas ligand , and phosphatidylserine were assessed . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Dietary lutein increased ( P < 0 . 05 ) lymphocyte proliferative response to all three mitogens and increased the percentages of cells expressing CD 5 , CD 4 , CD 8 and major histocompatibility complex class 2 ( MHC 2 ) molecules . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Their immunoprofile is remarkably similar : CD 1 , CD2+ , surface CD 3 ( but cytoplasmic CD3epsilon+ ) , CD 4 , CD 5 , CD7+ , CD 8 , CD 16 , CD56+ , CD 57 , TCRalphabeta , TCRgammadelta , negative for B cell and myelomonocytic markers . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Following euthanasia , mononuclear cells were isolated from the thymus , peripheral blood , spleen , lymph node and bone marrow , and were labeled for flow cytometric analysis using mouse anti rat monoclonal antibodies directed against CD 5 , CD 4 , and CD 8 antigenic markers . ^^^ Although the percentages of some T cell subsets in the other lymphoid organs / tissues were altered by ovariectomy or E 2 treatment at d 0 and 14 , all these changes had normalized by d 28 except for CD 5 and CD 4 cells in peripheral blood . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
These cells express the T cell antigens CD 2 and CD 5 on their surface , but not CD 7 , and they express CD 4 and CD 45 at numbers of molecules per cell typical for T lymphocytes . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
There was a reduction in total T ( CD 3 ) , CD 4 and CD 8 cells in DHF and demonstrated that a low level of CD 3 , CD 4 , CD 8 and CD 5 cells discriminated DHF from DF patients during the febrile stage of the illness . ^^^ The reduction in CD 3 , CD 4 , CD 8 , CD 5 cells correlated with the degree of thrombocytopenia in DHF ( p < 0 . 05 ) which suggests that these cells probably participate in a common pathogenetic mechanism . . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
However , an augmentation of T lymphoid cells expressing CD 4 ( + ) , CD 5 ( + ) , or both , were observed with age , as well as after OVX . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The main findings were the following : ( 1 ) in the thymus , CD 8 ( ) CD 4 ( ) cells increased , CD 5 ( + ) alphabeta TCR ( ) and CD 8 ( + ) CD 4 ( + ) thymocytes decreased , while the most mature cell subset appeared well preserved with ageing ; ( 2 ) in the lymph nodes , T helper and T cytotoxic lymphocytes decreased in the most aged animals . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
In the two cases where tissue was available for immunohistochemical study in frozen sections , neoplastic cells showed CD 56 ( Leu 19 ) + perforin+ Fas ligand ( FasL ) + CD 2 ( Leu5b ) CD 3 ( Leu 4 ) CD 4 ( Leu 3 ) CD 5 ( Leu 1 ) CD 7 ( Leu 9 ) CD 8 ( Leu 2 ) betaF 1 TCRdelta 1 phenotypes . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
FACS analyses showed that spleen contained a minor subset ( 10 15 % ) of CD 4 ( + ) and class 2 ( int ) DCs that also expressed the OX 41 Ag and the lymphoid related Ags CD 5 and CD 90 ( Thy 1 ) and a major ( 80 85 % ) subset of CD 4 ( ) / OX41 ( ) / CD5 ( ) and class 2 ( int ) DCs . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The maxillar mass biopsy revealed a T cell infiltration , and its immunologic characterization by flow cytometry showed a gammadelta T cell phenotype ( CD45+ , CD3+ , CD2+ , TCR gammadelta+ ) , without expression of CD 7 , CD 5 , CD1a , TdT , CD 4 , CD 8 , TCR alphabeta , or NK antigens ( CD 16 , CD 56 , and CD 57 ) . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
There was also loss of CD 4 and CD 8 ( n = 5 ) , loss of CD 5 and CD 7 ( n = 5 ) , complete loss of CD 3 ( n = 4 ) , coexpression of CD 4 and CD 8 ( n = 1 ) , and partial loss of CD 3 ( n = 1 ) . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
A 72 year old Caucasian man presented with a malignant neoplasm comprised of blastoid cells without azurophilic granules in the Giemsa stain , with positivity for CD 2 , CD 4 , HLA DR , CD 45 and CD 56 , and negativity for CD 3 ( surface and cytoplasmic ) and CD 5 . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The main outcome measures were lymphocyte subset and activation markers determined by two and three color flow cytometry ( CD 2 , CD 3 , CD 4 , CD 5 , CD 8 , CD 16 , CD 19 , CD 23 , CD 25 , CD 56 , and HLA DR ) . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Skin biopsies were taken at the same time points , fixed , sectioned , and stained with Giemsa for histologic evaluation , or with mouse anti swine monoclonal antibodies ( CD 1 , CD 2 , CD 4 , CD 5 , CD 8 , CD 25 , CD 45 , MHCII ) and with one mouse anti human monoclonal antibody ( CD62E ) cross reacting with swine for immunohistochemical evaluation . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The immunoregulatory cells , which include the T ( CD 3 ) , B ( CD 19 ) , CD 4 , CD 8 , CD 5 and natural killer ( NK ) cells were significantly lower in DHF compared to DF patients ( p < 0 . 05 ) . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
BCL 6 ( + ) cortical and medullary thymocytes also expressed CD 2 , CD 3 , CD 4 , CD 5 , CD 7 , or CD 8 . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
In human PBMNC jaundice reduced the percentages of CD 3 , CD 5 , CD 4 , CD 8 and HLA DR expressing cells and increased the proportion of CD 25 and perforin positive lymphocytes . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Expression of some leukocyte antigens ( including CD 45 ) and its isoforms ( CD 2 , CD 4 , CD 5 , CD 6 , CD 7 , and CD 8 ) was examined in the human periapical granulation tissue samples in the present study . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The atypical lymphocytes were positive for CD 2 , CD 3 , CD 5 , CD 7 , CD 56 and TCR gamma delta , but negative for CD 4 , CD 8 , CD 57 , TCR alpha beta and B cell antigens . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Most ( > 75 % ) agreed that at least one more B ( CD 20 , CD 22 , CD79a , IgM ) , T ( CD1a , CD 2 , CD 4 , CD 5 , CD 8 ) , myeloid ( CD11b , CD 15 , CD 64 , CD 117 , myeloperoxidase ) , erythroid ( CD 36 , CD 71 , glycophorin A ) , and megakaryocytic ( CD 41 , CD 61 ) reagents should be included in the essential panel . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
There was also a reduction in the number of circulating T cells expressing CD 4 ( P = 0 . 03 ) , CD 5 ( P = 0 . 05 ) and CD11a ( P = 0 . 01 ) . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
RA patients , whether active or inactive , showed a distinct phenotype when compared to healthy donors : ( 1 ) the percentage of CD 4 ( + ) CD 28 ( high ) cells was increased twofold and the CD 4 ( + ) CD 28 ( low ) subset was reduced twofold ( P < 0 . 01 ) and ( 2 ) the CD 4 ( + ) CD 28 ( high ) cells from RA patients showed an in vivo activated phenotype , CD45RO ( + ) CD 5 ( high ) IL 2Ralpha ( + ) ( P < 0 . 01 ) . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
However , CD 5 expression , which is mediated by pre TCR stimulation , was significantly suppressed on the CD 4 ( ) CD 8 ( ) thymocytes of the transgenic mice . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
CD 4 , CD 8 , CD 5 , CD 16 , CD 19 surface antigen positive lymphocyte subsets , serum IgG , IgM , and cortisol levels were assessed in all samples . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
In the population of viral antigen positive PBMC , 38 . 4+ / 4 . 5 % were CD 5 ( + ) T lymphocytes ( 18 . 1+ / 3 . 2 % CD 4 ( + ) 13 . 6+ / 1 . 8 % CD 8 ( + ) ) , 18 . 1+ / 5 . 4 % were B lymphocytes , 8 . 5+ / 3 . 9 % were monocytes and 35 % remained unidentified . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The lymphoma cell was positive for CD 20 and T cell lineage markers such as cytoplasmic CD 3 , CD 4 , and CD 5 and had a monoclonal rearrangement of the T cell receptor ( TCR ) gamma chain gene . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Both MoAbs and complement treatment of the transferred cells demonstrated that the phenotype of the early response cells which elicited a response at 6 h after challenge was Thy 1 ( + ) , B 220 ( + ) , alphabeta TCR ( ) , gammadelta TCR ( ) , CD 3 ( ) , CD 4 ( ) , CD 5 ( + ) and CD 8 ( ) . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
PROCEDURE : Lymphocyte subset populations were identified , using monoclonal antibodies to cell surface markers CD 5 , CD 4 , CD 8 , and IgG . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Bone marrow and lymph node biopsies showed a T cell lymphoproliferative disease expressing NKRs ( CD 2 ( + ) , CD 3 ( + ) , CD 4 ( + ) , CD 5 ( + ) , CD 7 ( + ) , CD 8 ( ) , CD 56 ( ) , CD 94 ( + ) , CD158a ( + ) , CD158b ( + ) , CD 161 ( ) , p 70 ( ) , TCRalphabeta ( 1 ) , TCRgammadelta ( 2 ) , TIA 1 ( ) ) . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
MAb to antigens CD 25 , CD 8 , CDw 50 , CD 5 , CD 4 , CD 7 , CD 3 , CD 71 , CD 34 , CD 45 , CD 38 , CD11b , CD 16 , and CD 95 have gained worldwide recognition at International HDLA Workshop Conferences . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Here we show that pMHC contact modulates the expression of CD 5 by naive CD 4 T cells in a process that requires the continued expression of p 56 ( lck ) . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The atypical cells showed a CD2+ , CD3epsilon+ , CD7+ , CD43+ , CD45R0+ , CD56+ , and CD 4 , CD 5 , CD 8 betaF 1 phenotype with expression of the latent membrane protein ( LMP ) 1 of EBV . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
A T cell line generated in this way ( called TM PTR 4 ) had a CD 3 ( + ) , CD 5 ( + ) , CD 4 ( ) , CD 8 ( + ) , CD 45 ( Ro+ ) , CD 56 ( ) immunophenotype and a HLA A2 . 1 restricted cytotoxic activity to PTR 4 peptide pulsed CIR A 2 ( HLA A2 . 1 ( + ) ) target cells , PTH rP ( + ) / HLA A2 . 1 ( + ) CIR A 2 transfected with PTH rP gene , prostate carcinoma LNCaP cells , and autologous metastatic prostate cancer cells ( M CaP ) . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
All tested patients had CD 2 , CD 7 , CD 4 , and / or CD 8 positivity , whereas CD 5 and CD 3 were positive in 98 % and 96 % of tested patients , respectively . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The present study shows that B cell deficiency leads to decreased CD 4 ( + ) T cell apoptosis during infection and compares FasL expression and killer function of B 1a and CD 5 ( ) B lymphocyte subsets . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
B cell markers , such as terminal deoxynucleotidyl transferase ( TdT ) , CD 10 , CD 19 , CD 20 and HLA DR were positive , and CD 2 , CD 3 , CD 4 , CD 5 , CD 7 , CD 8 , kappa , lambda , cytoplasmic mu and myeloperoxidase were negative . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The flow cytometric immunophenotype of the lymphoma cells was CD 2 , CD 3 , CD 4 , CD 5 , CD8+ , CD10+ , CD19+ , CD20+ , CD 23 , kappa+ , lambda , CD25+ , and CD 56 . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Flow cytometric immunophenotyping showed expression of CD 2 , CD 3 , and CD 7 with lack of expression of CD1a , CD 4 , CD 5 , CD 8 , and CD 56 . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Flow cytometry analysis of spleen cells from CD 5 ( null ) me ( 5 ) / me ( 5 ) mice at 9 12 weeks of age revealed significant decreases in percentages of IgM / B220 double positive B cells , Mac 1 / Gr 1 double positive cells and CD 4 ( + ) T cells compared with me ( 5 ) / me ( 5 ) mice . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
In all cases tested , tumor cells were immunoreactive for CD 3 , CD 4 , CD 5 , and CD 25 and were nonimmunoreactive for CD 7 and CD 8 . ^^^ The tumor cells in all cases tested were positive for CD 2 , CD 3 , CD 4 , CD 5 , and CD 25 and were negative for CD 7 . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Lymphocyte subgroups containing CD 4 , CD 5 , CD 6 , CD 8 , CD 19 , CD 23 , and CD 25 , and immunoglobulin G ( IgG ) , IgM , IgA , and IgE , were in the normal range ; hemoglobin F ( HbF ) , 2 . 8 % . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Tumor cells were negative for surface CD 3 , CD 5 , and CD 20 in all cases , but some patients showed expression of CD 2 ( three out of five ) , cytoplasmic CD 3 ( two out of seven ) , CD 4 ( six out of seven ) , and CD 16 ( three out of seven ) . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
In conditions of severe energy structural deficiency and impaired function of oxygen transport systems , CVD patients develop secondary immune deficiency presenting with depression of basic immunoregulatory subpopulations of T and B cellular immunity ( CD 2 , CD 3 , CD 4 , CD 5 , CD 8 , CD 16 , CD 22 ) . . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The protective roles of different lymphocyte subsets were investigated in a rat vaginal candidiasis model by adoptive transfer of vaginal lymphocytes ( VL ) or sorted , purified CD 3 ( + ) T cells , CD 4 ( + ) or CD 8 ( + ) T cells , or CD 3 ( ) CD 5 ( + ) B cells from the vaginas of nave or immune rats following three rounds of Candida albicans infection . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Unlike the CD 4 ( ) subset , CD 4 ( + ) splenic DC expressed CD 5 , CD 90 , and signal regulatory protein alpha molecules . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The tumor was composed of primitive lymphoid cells expressing CD 2 , CD 3 , CD 4 , CD 5 , CD 7 , CD 8 , and CD 10 . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
By flow cytometry , we have defined three distinct patterns of cytoskeletal association ; constitutive , inductive , and mAb crosslink induced , and assigned human and bovine CD 2 , CD 3 , CD 4 , CD 5 , CD 8 , CD 18 , CD 19 , CD 44 , CD45RA , CD45RO , alphabeta TCR , gammadelta TCR , E selectin ligands , and L selectin surface antigens to one of these respective patterns . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Hematoxylin and eosin stained sections were examined and immunophenotyping was carried out on paraffin embedded , formalin fixed tissue using antibodies to CD 2 , CD 3 , CD 4 , CD 5 , CD 7 , CD 8 , CD 20 , CD 30 , and CD 56 . ^^^ The aberrant phenotype cell is similar to that defining MF : a CD 4 positive T lymphocyte with a CD 5 and CD 7 deletion . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
At seven weeks after inoculation , mice were euthanized and the tracheobronchiolar and hilar lymph nodes were collected and stained for cell surface markers to T cells ( CD 3 , CD 4 , and CD 8 ) , B cells ( B 220 , CD 5 ) , natural killer ( NK ) cells ( pan NK ) and intracellular interleukin 10 ( IL 10 ) and interferon gamma ( IFN gamma ) . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Cytologic examination of the ascitic fluid revealed numerous abnormal lymphocytes which by flow cytometry demonstrated expression of CD 5 , CD 19 , CD 20 , and CD 4 . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The expression of CD 45 , CD 5 , CD 3 , and CD 4 followed a circadian rhythm . ^^^ Their acrophases suggested temporal association between CD 45 and CD 5 at the end of the active phase and between CD 4 and CD 3 at the beginning of this phase . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
CyA also had a differential effect on the thymic lymphocyte populations where there was little change in the Thy 1 bright , CD 5 dull , CD4+ , CD8+ cortical thymocytes but a depletion of the Thy 1 dull , CD 5 bright , CD 4 or CD 8 single positive medullary cells . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
There was no change in the percentage of CD 5 ( + ) CD 4 ( + ) T cells , MHC class 2 ( + ) cells , or ED 1 ( + ) macrophages . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
T cell lineage markers such as CD 4 , CD 5 , and cytoplasmic CD 3 were also positive . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
We conclude that AILT is mainly derived from CD 2 ( + ) CD 3 ( + ) CD 4 ( + ) CD 5 ( + ) CD 7 ( ) mature T helper cells with varying expression and partial loss of detectable CD 4 . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Tumor cells expressed CD 4 , CD 7 , CD 10 , CD45RB , CD 56 , CD 68 , and HLA DR and were negative for CD1a , CD 2 , sCD 3 , CD 5 , CD 13 , CD 14 , CD 20 , CD 33 , CD 34 , CD 43 , CD45RA , TIA 1 , S 100 , and TdT . cCD 3 was not detected in the immunostaining using paraffin tissue , but was faintly expressed in flow cytometry and immunostaining using a touch imprint slide . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Unexpectedly , in the present studies , the lack of CD 5 led to a remarkable increase of a CD 4 ( + ) TCRgammadelta T cell subset in CD 5 ( / ) beta ( / ) mice . ^^^ The CD 4 ( + ) TCRgammadelta T cells were also detectable in MHC 2 ( / ) CD 5 ( / ) beta ( / ) triple mutant mice . ^^^ In contrast , CD 5 ( + ) TCRgammadelta T cells suppressed the CD 4 ( + ) TCRgammadelta T cell mediated GC formation , presumably by eliminating this CD 4 ( + ) subset . ^^^ The lack of CD 5 also led to increased numbers of CD 4 ( + ) TCRgammadelta T cells in the colonic LP and increased susceptibility to development of chronic colitis in beta ( / ) mice . ^^^ Cell transfer studies suggest that CD 5 ( + ) TCRgammadelta T cells are capable of selectively eliminating CD 4 ( + ) TCRgammadelta T cells in the intestine . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
At least 1 T cell associated antigen was expressed in each case ( CD 2 , 12 / 17 [ 71 % ] ; CD 4 , 12 / 19 [ 63 % ] ; CD 3 , 6 / 19 [ 32 % ] ; CD 7 , 6 / 19 [ 32 % ] ; CD 5 , 5 / 19 [ 26 % ] ; CD 8 , 4 / 19 [ 21 % ] ) . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Immunohistochemical studies of the lymphoid infiltrate revealed a predominance of T cells , positive for CD 3 , CD 4 , CD 5 , and CD 56 . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Frozen sections of the tissues were immunohistochemically stained using monoclonal antibodies against surface markers CD 2 , CD 4 , CD 5 , CD 8 , B cell and granulocyte monocyte / macrophage and antiserum against specific granules of bovine eosinophils . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Evidence for activation of CD 4 ( + ) / TCRalphabeta ( + ) and TCRgammadelta ( + ) T cells relied on changes similar to those described for CD 8 ( + ) / TCRalphabeta ( + ) although less pronounced , except for higher levels of both CD 5 and CD 28 in the absence of reactivity for CD11c on CD 4 ( + ) / TCRalphabeta ( + ) T cells and higher levels of CD 161 and CD 94 on TCRgammadelta ( + ) T cells . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
M 20 subclones undergo several aspects of positive selection in response to co culture with a thymic stromal cell line ( St 3 ) , including down regulation of CD 4 and CD 8 , and up regulation of CD 5 and TCR . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The lymphoma cells were positive for CD 2 , CD 3 , CD 5 , CD 8 , and T cell receptor ( TCR ) beta F 1 , but negative for CD 4 , CD 19 , CD 20 , CD 103 , and CD 56 . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Light microscopy , immunohistochemical analysis using antibodies to CD 2 , CD 3 , CD 4 , CD 5 , CD 7 , CD 8 , and CD 30 in 6 cases , and polymerase chain reaction single stranded conformational polymorphism analysis for T cell receptor gamma chain gene rearrangement in 5 cases revealed 2 cytomorphologic patterns ( large cell dominant with polymorphous inflammation , small cell lymphocyte rich with an inconspicuous large cell component [ phenotypes , CD30+ / CD3+ / CD4+ / CD7 for large atypical cells ; reactive for small lymphocytes ] ) and clonal restriction in 4 and polyclonality in 1 of the lymphocyte dominant cases . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Exposure to larval antigen two thirds of the way through gestation resulted in significant reduction in the frequency of jejunal goblet cells and of ileal eosinophils , CD 1b ( + ) antigen presenting cells and CD 4 ( + ) , CD 5 ( + ) and CD 8 ( + ) cells . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
We studied the expression of CD 2 , CD 3 , CD 4 , CD 5 , CD 7 , CD 8 , CD 56 , and CD 138 in 447 cases of common human neoplasms with epithelioid features . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Immunophenotyping ( CD2+ CD 3 CD 4 CD 5 CD 8 CD16+ CD 56 ) confirmed NK cell leukemia . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The percentage of CD 4 ( + ) , CD 5 ( + ) , and CD 8 ( + ) cells decreased while the percentage of CD 14 ( + ) , IgM ( + ) , and MHC class 2 ( + ) cells increased significantly after endotoxin infusion . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The expression of different antigens ( CD 3 , CD 4 , CD8alpha , CD8beta , TCRalphabeta , TCRgammadelta , CD 5 , CD 22 and CD45R ) was analyzed by flow cytometry . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
PATIENTS AND METHODS : Forty cases diagnosed over a 12 year period were examined by immunohistochemistry with antibodies targeting CD 3 , CD 4 , CD 5 , CD 8 , CD 20 , CD 30 , CD 43 , CD45RO , CD 56 and CD 68 in paraffin embedded specimens . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
These data show that TCR alphabeta expressing lymphocytes that lack CD 5 expression are a major XCL 1 source , and that the contribution to its synthesis by different TCR alphabeta expressing T cell subsets , namely CD 4 ( + ) lymphocytes , is negligible . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Lymphocyte subsets were analysed by flow cytometry , using a whole blood indirect immunofluorescence technique and mAbs specific for feline CD 5 , CD 4 , CD 8 , CD 21 . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Although the epidermal layer in both cases was devoid histologically of significant epidermotropism , immunohistochemistry and polymerase chain reaction analyses of deeper samples that included involved adnexae confirmed aberrant antigen expression ( dominant CD 4 populations with apparent loss of CD 7 and / or CD 5 ) and T cell clonality , respectively . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
They hypothesize that the key event in T cell activation is the formation of multimolecular complexes consisting of the TCR and several other polypeptides , including CD 4 or CD 8 , CD 2 , CD 5 and the associated tyrosine kinases p 59 ( fyn ) and p 56 ( lck ) . . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Immunohistochemical staining revealed that these atypical lymphoid cells were positive for LCA , CD 45 , CD 5 , CD 20 , CD 3 epsilon , CD 8 , bcl 2 and bcl 6 and negative for CD 56 , CD 4 , CD 68 , keratin , S 100 , kappa and lambda . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The prothymocytes are positive for the terminal deoxynucleotidyl transferase ( TdT ) and give rise to cortical thymocytes , which express CD 1 , CD 2 , CD 3 , CD 5 , and both CD 4 and CD 8 . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The least mature cells ( double negative ) expressed low density CD 2 and CD 5 , high density CD 7 , CD 10 , CD 34 , and heterogeneous CD 4 and CD 8 . ^^^ The immature cells ( double positive ) expressed CD 2 , CD 5 , CD 7 , CD 4 , CD 8 , heterogeneous surface CD 3 , and intermediate density CD 45 . ^^^ The mature cells ( single positive ) expressed CD 2 , surface CD 3 , CD 5 , CD 7 , and CD 4 or CD 8 . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
METHODS : Peripheral blood lymphocyte subpopulations were analyzed by dual color flow cytometry by using monoclonal antibodies for the lymphocyte receptors CD 2 , CD 3 , CD 4 , CD 5 , CD 8 , CD 16 , CD 19 , CD11b , CD11c , and HLA DR . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Flow cytometric immunophenotype analysis showed that over 80 % of the cells were positive for CD 2 , CD 3 , CD 4 , CD 5 and CD 7 antigens and negative for terminal deoxynucleotidyl transferase and CD1a antigens . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
RESULTS : HR 8348 cell line did not express CD 2 , CD 3 , CD 4 , CD 5 , CD 7 , CD 8 , TCR , CD 10 , CD11b , CD 14 , CD 16 , CD 19 , CD 22 , CD 25 , CD 28 , SmIg , CD 33 , CD 35 , CD 36 , CD41a , CD 45 , CD45RA , CD45RO , CD 56 , CD 61 , CD 64 , CD66b , CD 69 , CD 71 , CD 117 , CD 122 and P glycoprotein but expressed CD 13 , CD 15 , CD 20 , CD 38 , CD 95 and HLA DR . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Numbers of the lymphocyte subsets ( CD 3 , CD 4 , CD 5 , CD 8 , CD21+ cells ) quantified by flow cytometry were similar between Przewalski ' s horses and domestic horses ( Equus caballus ) . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
We demonstrate here that , although both CD 5 ( + ) and CD 5 ( ) B cells , but not CD 4 ( + ) T , CD 8 ( + ) T and gammadeltaTCR ( + ) T cells , are protected from spontaneous ex vivo apoptosis in sheep infected with wild type and a mutant BLV that encodes a mutant Tax D247G protein with elevated trans activation activity , only CD 5 ( ) B cells become the main target for ex vivo survival when the disease proceeds to the persistent lymphocytotic stage , which showed an increased expansion of the CD 5 ( ) B cells . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The changes in the expression of CD 3 , CD 5 , CD 8 , CD 4 , CD 28 , CD 56 , and CD 19 were monitored in highly purified lymphocyte populations obtained by negative selection in a fluorescence activated cell sorter . ^^^ The kinetics of expression loss was rapid for CD 8 , CD 56 , and CD 28 , and more than 80 % of initial expression was lost in the early stages of apoptosis but was slower for CD 3 , CD 5 , and CD 4 . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
We also observed a net decrease in peripheral activated CD 4 ( + ) T cells in CD 5 ( / ) spleens and DLN 10 days after immunization . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
MATERIAL / METHODS : To further elucidate phenotypic differences of T cell subsets , and begin to determine what information relative antigen density contributes to immunology , we analyzed normal human peripheral blood T cells for a variety of immunophenotypic ( CD 2 , CD 3 , CD 4 , CD 5 , CD 7 , CD 8 , CD45RA , CD45RO , TCR alpha beta ) and light scatter characteristics using 6 color flow cytometry . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Both large and small malignant cells were positive for CD43 / MT1 T cell associated antigen , perforin , granzyme B and TIA 1 , but negative for CD 2 , CD 3 , CD 5 , CD 7 , CD 4 and CD 8 antigens . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The flow cytometric analysis revealed that the blasts were positive for CD 19 , CD 20 , CD 22 , cytoplasmic ( Cyt ) CD79a , CD 10 , Cyt CD 3 , CD 5 , CD 7 , CD 4 , HLA DR , TdT , and were negative for myeloid markers . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Nb 2 cells were negative with CD 5 , OX 40 and CD 4 , whilst CD 8 stained only a minor fraction ( 1 % ) and certain variant clones of the cell line . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Peripheral blood flow cytometry showed the presence of a clonal population of T cells that expressed CD 4 and CD 5 but showed a loss of CD 7 . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The stability constants of the Cd 4 and Cd 5 complexes or Pb 4 and Pb 5 complexes were determined by use of pH titration . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Immune system tests including white blood cell count , lymphocyte count , T and B cells subgroups ( CD 2 , CD 4 , CD 5 , CD 7 , CD 8 , CD 16 , CD 20 , CD 22 , CD 56 ) , mitotic reaction to phytohaemagglutinin in lymphocyte culture . ^^^ Significant differences in mean lymphocyte number , and CD 2 , CD 4 , CD 5 , CD 8 , CD 16 ratios between the two groups were defined ( P < 0 . 05 ) . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
In vitro restimulation of PBMC with EHV 1 induced IFN gamma production by a significantly higher percentage of total ( CD 5 ( + ) ) T lymphocytes , and CD 4 ( + ) and CD 8 ( + ) T lymphocyte subsets among post EHV 1 infection PBMC samples compared to pre infection samples . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
At 18 26 months EBNA 1 transgenic mice did not differ from littermate control in ultimate body weight , in spleen size or weight , in lymph node , kidney , liver , or spleen histology , in splenocyte fractions positive for cluster of differentiation ( CD ) 3epsilon , CD 4 , CD 8 , CD62L , B 220 , CD 5 , IgM , IgD , MHC class 2 , CD11b , or CD 25 , or in serum IgM , IgG , or total Ig levels . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Immunophenotype analysis showed that lymphocytes were positive for CD 2 , CD 3 , CD 5 , CD 7 , CD 8 , and TCR gammadelta antigens and negative for CD1a , CD 4 , and TCR alphabeta antigens . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
This report is the first to describe the clinical , histologic , immunophenotypic , and molecular features of 2 cases of intravascular lymphoma with an NK cell phenotype ( CD3epsilon+ , CD2+ , CD7+ , CD56+ , T cell intracytoplasmic antigen 1+ , perforin+ , granzyme B+ , CD 20 , CD 4 , CD 5 , CD 8 , T cell receptor [ TCR ] betaF 1 ) . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
To understand the target specificity of SHM in AID expressing T lymphomas , we sequenced six oncogenes ( c myc , pim 1 , p 53 , atm , tgfbr 2 , and k ras ) and two genes ( cd 4 and cd 5 ) that are actively transcribed in T lymphomas . ^^^ SHM was found only in c myc , pim 1 , cd 4 , and cd 5 , which share the E 47 binding motif in the enhancer / promoter . ^^^ SHM base specificities in the CD 4 and CD 5 genes were biased to AT , indicating that the preference of target bases of the mutations generated by overexpression of AID is not always GC bases but variable between target genes . . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
PIT was associated with a significant increase in surface expression of CD 5 on both CD 4 ( + ) and CD 8 ( + ) PBMCs . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Immunohistochemical staining showed positive reactions to CD 3 , CD 8 , CD 43 , CD45RO , CD 56 , and T cell intracellular antigen 1 , but negative reactions to CD 4 , CD 5 , CD 20 , CD 23 , and CD 57 . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The T cells expressed CD 2 , CD 3 , CD 5 , CD 7 , and CD 8 , with partial loss of CD 4 . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Double staining analyses showed that lymphocytes expressing high levels of PNA binding glycans ( PNA ( high ) lymphocytes ) were made up of the great majority of CD 5 ( + ) , CD 4 ( + ) and CD 8 ( + ) cells , and of 30 and 50 % of sIg bearing lymphocytes in peripheral blood and in lymph nodes or spleen , respectively . ^^^ Contrary to what is found in humans and mice , PNA staining intensity on CD 5 ( + ) , CD 4 ( + ) and CD 8 ( + ) cells did not differentiate immature from mature T lymphocytes in the equine thymus . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Comprehensive immunophenotypic analysis showed that the MCL cells expressed the typical B lymphocytic markers , were CD 5 and CD 8 positive , but did not express other T cell proteins , such as CD 2 , CD 3 , CD 4 , CD 7 , TCRalphabeta and TCRgammadelta . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Expression of the T cell antigens CD 2 , CD 3 , CD 4 , CD 5 , CD 7 and CD 8 was assessed by immunohistochemistry . ^^^ In all , 12 cases ( 5 % ) expressed at least one T cell marker in the following order : CD 2 in 11 cases , CD 4 in five , CD 3 in two , and CD 5 and CD 8 in one case each ; there were no CD 7 positive cases , and five cases ( 2 % ) expressed more than one T cell antigen . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
SIT ( / ) double positive thymocytes show an upregulation of the activation markers CD 5 and CD 69 , suggesting that SIT negatively regulates TCR mediated signals at the CD 4 ( + ) CD 8 ( + ) stage of thymic development . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Flow cytometric analysis of the bone marrow showed positivity for CD 2 , CD 3 , CD 4 , CD 5 and CD 7 . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
These cells were immunohistochemically positive for CD 3 , CD 5 , CD 7 , CD 8 , CD 16 , CD 56 , T cell receptor 33 ( TCR 33 ) , T cell intracellular antigen 1 , and granzyme B but were negative for CD 4 , CD 30 , CD 57 , and TCR 33 . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
By contrast , HGMC did not express detectable amounts of CD 1 , CD 2 , CD 4 , CD 5 , CD 14 , CD 15 , CD 16 , CD 22 , CD 24 , CD 25 , CD 26 , CD 27 , CD 28 , CD 31 , CD 32 , CD 34 , CD 35 , CD 88 , or CD 116 . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
In addition , CD4+CD25+ T cells develop normally in Tcralpha+ / mice and we show for the first time that despite expressing only one TCRalpha chain , they retain their characteristic CD 4 ( low ) , CD 3 ( low ) , TCRbeta ( low ) , CD 5 ( high ) , CD45RB ( low ) and cytoplasmic CD 152 ( high ) phenotype . . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
After applying these antibodies in combination with antibodies against CD 3 , CD 5 , CD 4 , CD 8 , and cytotoxic molecules , double stains were evaluated by confocal laser scanning microscopy . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
In frozen tissue sections , neoplastic cells mostly showed CD 3 ( Leu 4 ) , CD 4 ( Leu3a ) , CD 5 ( Leu 1 ) , CD 8 ( Leu 2 ) , CD 16 ( Leu 11 ) , CD 56 ( Leu 19 ) + , betaF 1 , TCRdelta 1 , perforin+ , CD94+ phenotypes . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Anti CD 4 , CD 5 , micro chain , CD 25 and RLA 2 monoclonal antibodies were used . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Low density of CD 4 and CD 2 , CD 4 and CD 5 , the presence of CD 7 were registered in 1 patient each . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Peripheral lymphocytes were double stained with multiple fluorescent antibody combinations : anti CD 3 plus anti gammasigmaT cell receptor ; anti CD 19 plus anti CD 5 ; anti CD 4 plus anti CD45RA ; or anti CD 8 plus anti CD11b . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
By immunohistochemical examination , the phenotypes of NP cells were determined as CD 1 , CD 4 , CD 5 , CD8alpha , sIgM+ , lambda light chain+ , B B4+ , MHC class II+ in both case . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The neoplastic populations expressed CD 2 , CD 4 , CD 5 , and CD45RO in all cases , lacked expression of CD 8 and CD 56 in all cases , and showed negative or dim surface CD 3 in most cases . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Subclasses of T , B and NK lymphocytes were tested for in the blood samples : CD 3 , CD 4 , CD 5 , CD 7 , CD 8 , CD11B , CD 16 , CD 20 , CD 25 , CD 38 , CD45RA , CD 50 , CD 71 and CD 95 . ^^^ Changes were observed in the following T cell subclasses : CD 3 , CD 4 , CD 5 and CD 8 . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
A portion of each skin specimen was stored at 80 degrees C and later examined using monoclonal antibodies against CD 2 , CD 3 , CD 4 , CD 5 , CD 8 , CD 15 , CD 19 , CD 20 and CD 30 . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Parameters of blood acid base equilibrium were measured simultaneously with evaluation of TLC and SLCs . ( Antigens CD 3 , CD 4 , CD 5 , CD 8 , CD 19 , CD16+56 were determined using flow cytometry . ) The study patients showed compensated metabolic acidosis ( pH : 7 . 40 + / 0 . 04 ; HCO 3 : 22 . 9 + / 2 . 4 mmol / L ) . ^^^ Patients on PD who show better correction of metabolic acidosis also show higher TLC and CD 3 , CD 4 , CD 5 , and CD 8 cell counts . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
Immunophenotyping was performed to evaluate expression of CD 2 , CD 3 , CD 4 , CD 5 , CD 7 , CD 8 , CD 20 , CD 30 , and MIB 1 . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
TLI was analyzed using a fluorescence activated cell sorter ( FACS ) scan and fluorescence antibodies CD 3 , CD 4 , CD 5 , CD 8 , CD 10 , and CD 19 and kappa and lambda light chains . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The OX 62 ( + ) CD 4 ( + ) subset of VDCs displayed a lymphoid cell like morphology and expressed the T cell antigen CD 5 , whereas the OX 62 ( + ) CD 4 ( ) VDC subset exhibited a myeloid morphology and was CD 5 negative . ^^^ CD 5 ( ) CD 4 ( ) CD 86 ( ) CD 80 ( ) CD134L ( + ) VDCs from infected , but not noninfected , rats spontaneously released large amounts of interleukin 12 ( IL 12 ) and tumor necrosis factor alpha , whereas all VDC subsets released comparable levels of IL 10 and IL 2 cytokines . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
This report examined correlates of immunodeficiency in wild and captive lions and pumas by quantifying CD 5 ( + ) , CD 4 ( + ) , and CD 8 ( + ) T cell subsets . ^^^ The FIV Pco infected pumas had a more generalized response of lymphopenia expressed as a significant decline in total lymphocytes , CD 5 ( + ) T cells , and CD 5 ( ) lymphocytes as well as a significant reduction in CD 4 ( + ) T cells . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
The World Health Organization ( WHO ) suggested immunophenotype for pre T ALL / LBL typically includes the expression of TdT , cCD 3 , and CD 7 , while CD 2 , CD 3 , CD 4 , CD 5 , CD 8 , and CD 10 are variably expressed . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
RESULTS : PTs were positively stained with 3G8 and Leu 1 1b against Fc gamma RIII , partially stained with MAb against MHC class 1 , but not with 32 . 2 ( Fc gamma RI ) , IV 3 ( Fc gamma RII ) , or MAbs against CD 4 , CD 19 , or CD 56 , indicating that only low affinity receptor , Fc gamma RIII , is expressed on PTs . ^^^
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA
Interacting proteins: P06127 and P01730	Pubmed	SVM Score :0.0
NA