| Interacting proteins: P01138 and P00747 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P01138 and P00747 |
Pubmed |
SVM Score :0.0 |
| Plasminogen activator activity was found in the 7S NGF and HMW EGF , as well as in the gamma subunit and EGF binding protein . ^^^ The gamma 1 , gamma 2 and gamma 3 subunits of 7S NGF showed plasminogen activator activity almost equal to that of the original gamma subunit . . ^^^ |
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| Interacting proteins: P01138 and P00747 |
Pubmed |
SVM Score :0.0 |
| This action of NGF in vivo is not mediated by its nerve growth promoting properties nor its plasminogen activating property . . ^^^ |
|
| Interacting proteins: P01138 and P00747 |
Pubmed |
SVM Score :0.0 |
| We have now employed cDNA representational difference analysis to identify four genes ( activity regulated cytoskeletal protein , collagenase 1 , plasminogen activator inhibitor 1 , and VH6 / MKP 3 ) as genes preferentially induced withing 4 hours by NGF in PC 12 cells . . ^^^ |
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| Interacting proteins: P01138 and P00747 |
Pubmed |
SVM Score :0.0 |
| All of the neurotrophins tested nerve growth factor ( NGF ) , brain derived neurotrophic factor ( BDNF ) , neurotrophin 3 ( NT 3 ) , and neurotrophin 4 ( NT 4 ) , increased the secretion of plasminogen and urokinase type plasminogen activator and specific activity of acid phosphatase , but suppressed the release of constitutively produced and lipopolysaccharide stimulated nitric oxide ( NO ) from microglia . ^^^ |
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| Interacting proteins: P01138 and P00747 |
Pubmed |
SVM Score :0.0 |
| The single , highly stable form of mouse submandibular gland nerve growth factor ( NGF ) , prepared as described by Young et al . [ ( 1978 ) Biochemistry 17 , 1490 1498 ] is a protease of restricted specificity that can convert plasminogen to plasmin . ^^^ In the absence of plasminogen , NGF is not fibrinolytic , nor does it hydrolyze casein at a measurable rate . ^^^ Treatment of NGF with diisopropyl fluorophosphate inhibits its ability to activate plasminogen as well as its capacity to hydrolyze certain synthetic arginine esters . ^^^ Since NGF is known to be secreted at high concentrations in mouse saliva , it may serve to activate plasminogen ( with subsequent fibrinolysis ) somewhere in the alimentary tract . ^^^ Plasminogen activation is the only known action of NGF upon a biologically important non neural substrate . . ^^^ |
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| Interacting proteins: P01138 and P00747 |
Pubmed |
SVM Score :0.0 |
| Infusion of 15 ng / h of NGF with a mini osmotic pump for 14 days resulted in a 2 fold increase of ABP mRNA as revealed by Northern blots , whereas the mRNA level of another Sertoli cell protein , urokinase type plasminogen activator , remained unchanged . ^^^ |
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| Interacting proteins: P01138 and P00747 |
Pubmed |
SVM Score :0.0 |
| The resulting plasminogen activator activity in conditioned medium was high in ( But ) 2cAMP treated cultures with short neuritic outgrowth but remained low in NGF or NGF plus ( But ) 2cAMP treated cultures , where neurite extension was , respectively , large and very large . ^^^ |
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| Interacting proteins: P01138 and P00747 |
Pubmed |
SVM Score :0.0 |
| The urokinase plasminogen activator receptor ( UPAR ) is preferentially induced by nerve growth factor in PC 12 pheochromocytoma cells and is required for NGF driven differentiation . ^^^ A `` second generation ' ' representational difference analysis procedure now identifies the urokinase plasminogen activator receptor ( UPAR ) as a gene that is much more extensively induced by NGF than by EGF in PC 12 cells . ^^^ |
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| Interacting proteins: P01138 and P00747 |
Pubmed |
SVM Score :0.0 |
| Nerve growth factor ( NGF ) , which acts as a neurotrophic factor in a rat pheochromocytoma cell line ( PC 12 ) , stimulated type 1 plasminogen activator inhibitor ( PAI 1 ) mRNA expression from 1 to 5 h , after addition at 5 ng / ml . ^^^ |
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| Interacting proteins: P01138 and P00747 |
Pubmed |
SVM Score :0.0 |
| Wnt 1 decreased the NGF induced expression of the late response gene SCG 10 but not of the immediate early genes , fos , Nur 77 and UPAR ( urokinase type plasminogen activator receptor ) nor of the late response genes GAP 43 and collagenase . ^^^ |
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| Interacting proteins: P01138 and P00747 |
Pubmed |
SVM Score :0.0 |
| We previously identified the urokinase plasminogen activator receptor ( UPAR ) as a gene induced by nerve growth factor ( NGF ) , but not by epidermal growth factor ( EGF ) , in PC 12 cells ( Farias Eisner et al . [ 2000 ] J . ^^^ |
|
| Interacting proteins: P01138 and P00747 |
Pubmed |
SVM Score :0.0 |
| At a late stage of tumor development , an increase of telomerase activity , an over expression of growth factors and / or their receptors ( EGF , NGF , gastrin , bombesin ) , of proangiogenic factors ( VEGF , FGF , PDGF ) , of invasiveness factors ( metalloproteinases , E cadherin , urokinase and tissue plasminogen activators ) occur . ^^^ |
|
| Interacting proteins: P01138 and P00747 |
Pubmed |
SVM Score :0.0 |
| The expression of nerve growth factor ( NGF ) and plasminogen activator inhibitor 1 ( PAI 1 ) fell after differentiation , whereas that of TNF alpha and IL 6 changed little . ^^^ |
|
| Interacting proteins: P01138 and P00747 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P01138 and P00747 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P01138 and P00747 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P01138 and P00747 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P01138 and P00747 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P01138 and P00747 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P01138 and P00747 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P01138 and P00747 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P01138 and P00747 |
Pubmed |
SVM Score :0.0 |
| NA |
|