| Interacting proteins: P01133 and P04004 |
Pubmed |
SVM Score :0.0 |
| Because of the large amounts of EGF receptor present on A 431 human carcinoma cells , these cells were used to study further the relationship between the phosphorylation state of threonine 654 , the tyrosine phosphorylation state of the receptor , and the receptor ' s protein tyrosine kinase activity toward exogenous substrates . ^^^ |
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| Interacting proteins: P01133 and P04004 |
Pubmed |
SVM Score :0.0 |
| A synthetic Arg Gly Asp Ser tetrapeptide ( RGDS ) , specific for fibronectin and vitronectin adhesion receptors , inhibited TRH , EGF , and TPA induced GH 4 cell stretching and attachment to fibronectin and vitronectin coated dishes . ^^^ Because the str variant has RGDS specific binding sites for fibronectin and vitronectin and responds to some agents that induce cell stretching via an RGDS receptor , we conclude that the a 14 str variant has a defect in an intracellular signaling pathway , shared by TRH and EGF , which induces cell stretching . . ^^^ |
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| Interacting proteins: P01133 and P04004 |
Pubmed |
SVM Score :0.0 |
| The EGFR specific tyrosine kinase inhibitor tyrphostin 25 selectively prevents EGFR autophosphorylation thereby preventing the EGF induced FG cell migration response on vitronectin without affecting constitutive migration on collagen . ^^^ In this case , PKC activation appears to be associated with and downstream of EGFR signaling since calphostin C , an inhibitor of PKC , blocks FG cell migration on vitronectin induced by either PKC or EGF . ^^^ |
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| Interacting proteins: P01133 and P04004 |
Pubmed |
SVM Score :0.0 |
| We investigated the synergistic effects of SP with ( 1 ) growth factors : epidermal growth factor ( EGF ) , basic fibroblast growth factor ( bFGF ) , and transforming growth factor beta ( TGF beta ) ; ( 2 ) extracellular matrix proteins : fibronectin , vitronectin , laminin , and collagen type 4 ; and ( 3 ) cytokines : interleukin 1alpha ( IL 1alpha ) , IL 1beta , and interleukin 6 ( IL 6 ) . ^^^ EGF , fibronectin , vitronectin , collagen type 4 , and IL 6 stimulated epithelial migration , but bFGF , TGF beta , laminin , IL 1alpha , and IL 1betadid not . ^^^ |
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| Interacting proteins: P01133 and P04004 |
Pubmed |
SVM Score :0.0 |
| Tumor cells expressing EGFR either endogenously ( MDA MB 231 , MTLn 3 ) or , for the human EGFR , ectopically ( MTC HER1 / 1 ) in intermediate amounts exhibited , upon EGF addition , increased cellular adhesion to various ECM proteins , such as fibronectin , collagens and vitronectin . ^^^ |
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| Interacting proteins: P01133 and P04004 |
Pubmed |
SVM Score :0.0 |
| In mouse B82L fibroblasts transfected with the full length EGF receptor , EGF promotes cell rounding and attenuates cell spreading on fibronectin , laminin , and vitronectin , and thus appears to reduce the strength of cell adhesion . ^^^ |
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| Interacting proteins: P01133 and P04004 |
Pubmed |
SVM Score :0.0 |
| Interestingly , protein modules such as EGF domains ( meprin Aalpha fragments ) , somatomedin B domains ( vitronectin fragments ) , thyroglobulin domains ( insulin like growth factor binding proteins ) , and Kazal type inhibitor domains were identified . ^^^ |
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| Interacting proteins: P01133 and P04004 |
Pubmed |
SVM Score :0.0 |
| HGF / SF , but not EGF , selectively promotes cell adhesion on laminins 1 and 5 , fibronectin , and vitronectin through a PI 3 K dependent mechanism . ^^^ |
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| Interacting proteins: P01133 and P04004 |
Pubmed |
SVM Score :0.0 |
| It binds collagen 4 , laminin 1 , entactin / nidogen 1 , fibronectin and vitronectin , but not collagen 1 , heparin or EGF . ^^^ |
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| Interacting proteins: P01133 and P04004 |
Pubmed |
SVM Score :0.0 |
| Using a MAPK cascade inhibitor , PD 98059 , it was shown that EGF induced migration on collagen was mediated by MAPK whereas EGF induced migration on fibronectin and vitronectin was not . ^^^ |
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| Interacting proteins: P01133 and P04004 |
Pubmed |
SVM Score :0.0 |
| RESULTS : We demonstrate that insulin like growth factor ( IGF ) 1 used in conjunction with epidermal growth factor ( EGF ) , insulin like growth factor binding protein ( IGFBP ) 5 and vitronectin supports growth in the absence of serum . ^^^ CONCLUSIONS : IGF 1 used in conjunction with IGFBP 5 , EGF , and vitronectin provides a superior alternative to serum for the rapid expansion and transplantation of cultured keratinocytes within the first week of treatment . ^^^ |
|
| Interacting proteins: P01133 and P04004 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P01133 and P04004 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P01133 and P04004 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P01133 and P04004 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P01133 and P04004 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P01133 and P04004 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P01133 and P04004 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P01133 and P04004 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P01133 and P04004 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P01133 and P04004 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P01133 and P04004 |
Pubmed |
SVM Score :0.0 |
| NA |
|