| Interacting proteins: Q99417 and P01106 |
Pubmed |
SVM Score :0.0 |
| AMY 1 , a novel C MYC binding protein that stimulates transcription activity of C MYC . ^^^ RESULTS : We cloned two cDNAs which encode a novel C MYC binding protein of 11 kDa , designated AMY 1 ( Associate of C MYC ) . ^^^ AMY 1 was bound via its C terminal region to the N terminal region of C MYC ( amino acids nos 58 148 ) corresponding to the transactivation domain . ^^^ AMY 1 was localized in the cytoplasm in cells expressing c myc at low levels , but in the nucleus in the cells of a high c myc expression in transiently transfected cells . ^^^ A similar difference in endogenous AMY 1 localization was observed during the cell cycle : AMY 1 translocated from cytoplasm to nucleus during the S phase when c myc expression was increased . ^^^ |
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| Interacting proteins: Q99417 and P01106 |
Pubmed |
SVM Score :0.0 |
| We have reported that a novel c Myc binding protein , AMY 1 , stimulated the transcription activity of c Myc and was translocated from cytoplasm to nuclei in a c Myc dependent manner . ^^^ AMY 1 expression was up regulated after differentiation induction of human K 562 cells to erythrocyte cells by AraC , while c Myc expression was rapidly down regulated . ^^^ These results suggest that AMY 1 is a trigger for K 562 cells to differentiate to erythrocyte cells and that AMY 1 may have a function independent of or different from c Myc . . ^^^ |
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| Interacting proteins: Q99417 and P01106 |
Pubmed |
SVM Score :0.0 |
| AMY 1 , a c Myc binding protein , is localized in the mitochondria of sperm by association with S AKAP 84 , an anchor protein of cAMP dependent protein kinase . ^^^ We have reported that a novel c Myc binding protein , AMY 1 ( associate of Myc 1 ) , stimulated the transcription activity of c Myc . ^^^ |
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| Interacting proteins: Q99417 and P01106 |
Pubmed |
SVM Score :0.0 |
| AMY 1 has been identified by us as a c Myc binding protein and was found to stimulate c Myc transcription activity . ^^^ |
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| Interacting proteins: Q99417 and P01106 |
Pubmed |
SVM Score :0.0 |
| AMY 1 has been identified by us as a c Myc binding protein and was found to stimulate c Myc transcription activity . ^^^ |
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| Interacting proteins: Q99417 and P01106 |
Pubmed |
SVM Score :0.0 |
| We have reported that a novel c Myc binding protein , AMY 1 , stimulated the transcription activity of c Myc and was translocated from the cytoplasm to the nucleus in a c Myc dependent manner . ^^^ |
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| Interacting proteins: Q99417 and P01106 |
Pubmed |
SVM Score :0.0 |
| AMY 1 ( associate of Myc 1 ) was originally identified as a c Myc binding protein that enhances the c Myc transcription activity , and subsequently found to interact with A kinase anchoring proteins ( AKAPs ) , including AKAP 149 , S AKAP 84 and AKAP 95 . ^^^ AMY 1 ( associate of Myc 1 ) was originally identified as a c Myc binding protein that enhances the c Myc transcription activity , and subsequently found to interact with A kinase anchoring proteins ( AKAPs ) , including AKAP 149 , S AKAP 84 and AKAP 95 . ^^^ |
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| Interacting proteins: Q99417 and P01106 |
Pubmed |
SVM Score :0.0 |
| Over expressed ZF 5 gene product , a c myc binding protein related to GL 1 Kruppel protein , has a growth suppressive activity in mouse cell lines . ^^^ |
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| Interacting proteins: Q99417 and P01106 |
Pubmed |
SVM Score :0.0 |
| We have isolated the cDNA encoding a novel c Myc binding protein , MM 1 , by the yeast two hybrid screening of a human HeLa cell cDNA library . ^^^ |
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| Interacting proteins: Q99417 and P01106 |
Pubmed |
SVM Score :0.0 |
| We found that mRNAs encoding for cyclophilin A , c myc binding protein 1 , the heat shock protein 90alpha and one unknown transcript were up regulated in the oral cancer cell lines analysed as well as in HOK 16B cells . ^^^ |
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| Interacting proteins: Q99417 and P01106 |
Pubmed |
SVM Score :0.0 |
| Structures and comparison of genomic and complementary DNAs of mouse MSSP , a c Myc binding protein . ^^^ |
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| Interacting proteins: Q99417 and P01106 |
Pubmed |
SVM Score :0.0 |
| MM 1 , a c Myc binding protein , is a candidate for a tumor suppressor in leukemia / lymphoma and tongue cancer . ^^^ |
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| Interacting proteins: Q99417 and P01106 |
Pubmed |
SVM Score :0.0 |
| Recruitment of a transcriptional corepressor complex to c Myc by MM 1 , a c Myc binding protein . ^^^ We have reported that a novel c Myc binding protein , MM 1 , repressed the E box dependent transcription activity of c Myc ( Mori , K . , Maeda , Y . , Kitaura , H . , Taira , T . , Iguchi Ariga , S . ^^^ |
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| Interacting proteins: Q99417 and P01106 |
Pubmed |
SVM Score :0.0 |
| Physical interaction of p 73 with c Myc and MM 1 , a c Myc binding protein , and modulation of the p 73 function . p 73 shares high sequence homology with the tumor suppressor p 53 . ^^^ We found MM 1 , a nuclear c Myc binding protein , was associated with p 73 alpha in both yeast two hybrid and in vitro pull down assays . ^^^ |
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| Interacting proteins: Q99417 and P01106 |
Pubmed |
SVM Score :0.0 |
| The tumors studied lacked N myc overexpression , while showing up regulation of basic transcription factors , growth factors and receptors such as NSEP , c myc binding protein MM 1 , thymosin beta 10 ( TMSB 10 ) , TNF R superfamily member 10A ( TNFRSF10A ) and FZ 9 . ^^^ |
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| Interacting proteins: Q99417 and P01106 |
Pubmed |
SVM Score :0.0 |
| While a few genes appear slightly overexpressed in nevi , a number of genes involved in regulating cell proliferation were upregulated in melanoma , such as cyclin D 1 , cdc 2 related protein kinase , c Myc binding protein , early growth response protein 1 , and pleiotrophin . `` Housekeeping ' ' genes such as glyceraldehyde 3 phosphate dehydrogenase were expressed at similar levels in melanoma and nevi . ^^^ |
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| Interacting proteins: Q99417 and P01106 |
Pubmed |
SVM Score :0.0 |
| Enolase alpha and c myc binding protein ( MBP 1 ) originate from a single gene through alternative use of translational starting sites . ^^^ |
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| Interacting proteins: Q99417 and P01106 |
Pubmed |
SVM Score :0.0 |
| Interestingly , only three were affected in a similar fashion in both cell lines : c myc binding protein MM 1 , 23 kDa highly basic protein , and interferon inducible protein 9 27 ( IFITM 1 ) . ^^^ |
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| Interacting proteins: Q99417 and P01106 |
Pubmed |
SVM Score :0.0 |
| We showed that the expression of c myc binding protein ( MYCBP ) in colon carcinoma cells was consistently upregulated by overexpressed LEF 1 , which is confirmed by microarray data , RT PCR and luciferase assay . ^^^ |
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| Interacting proteins: Q99417 and P01106 |
Pubmed |
SVM Score :0.0 |
| MM 1 was identified as a c Myc binding protein and has been reported to repress the E box dependent transcription activity of c Myc by recruiting HDAC 1 complex via TIF 1 beta / KAP1 . ^^^ |
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| Interacting proteins: Q99417 and P01106 |
Pubmed |
SVM Score :0.0 |
| The isolation of the mouse MM 1 ; c Myc binding protein ( Myc Modulator 1 ) cDNA is described . ^^^ |
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| Interacting proteins: Q99417 and P01106 |
Pubmed |
SVM Score :0.0 |
| Among these proteins , we pointed out c Myc binding protein 1 , 53BP1 , Mdm 4 , OSBP related protein 3 and Mortalin as putative candidates to BCR ABL targets in chronic phase . ^^^ |
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| Interacting proteins: Q99417 and P01106 |
Pubmed |
SVM Score :0.0 |
| NA |
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