| Interacting proteins: Q02750 and P01106 |
Pubmed |
SVM Score :0.0 |
| The membranes were stained with amido black , scanned and tested separately with the nine monoclonal antibodies p 53 , c myc , PCNA , MEK 1 , pan ras , Cip 1 , Cdc 2 , Kip 1 , and TCTP . ^^^ |
|
| Interacting proteins: Q02750 and P01106 |
Pubmed |
SVM Score :0.0 |
| Activation of Raf , 5 Src , and MEK 1 led to induced expression of c Myc and cyclin D 1 . ^^^ |
|
| Interacting proteins: Q02750 and P01106 |
Pubmed |
SVM Score :0.0 |
| Ectopic expression of a constitutively active form of MEK 1 in cells expressing CSF 1R ( Y809F ) rescued c Myc expression and S phase entry , but only in the presence of CSF 1 induced cooperating signals . ^^^ Therefore , MEK 1 participates in an obligate signaling pathway linking CSF 1R to c Myc expression , but other signals from CSF 1R must cooperate with the MEK / ERK pathway to induce c Myc expression and S phase entry in response to CSF 1 stimulation . . ^^^ |
|
| Interacting proteins: Q02750 and P01106 |
Pubmed |
SVM Score :0.0 |
| The data obtained demonstrate that the growth factor activity of PAs is associated with : a rapid transient activation of early response genes , c fos , c jun and c myc ; the subsequent coordinated down regulation of p 53 and p21CIP1 ; the constant expression of the MEK 1 mRNA in every phase of the cell cycle . ^^^ |
|
| Interacting proteins: Q02750 and P01106 |
Pubmed |
SVM Score :0.0 |
| MEK 1 inhibitor PD 98059 blocked both the c myc and the c fos responses to Epo . ^^^ |
|
| Interacting proteins: Q02750 and P01106 |
Pubmed |
SVM Score :0.0 |
| These data indicate that the antiproliferative effects of raxofelast in H ( 2 ) O ( 2 ) stimulated rat aortic smooth muscle cells may involve the suppression of intracellular reactive oxygen species formation and the inhibition of ERKs by inactivation through PKC and MEK 1 , 2 and down regulation of c myc expression , regardless of Ras activation . . ^^^ |
|
| Interacting proteins: Q02750 and P01106 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q02750 and P01106 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q02750 and P01106 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q02750 and P01106 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q02750 and P01106 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q02750 and P01106 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q02750 and P01106 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q02750 and P01106 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q02750 and P01106 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q02750 and P01106 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q02750 and P01106 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q02750 and P01106 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q02750 and P01106 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q02750 and P01106 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q02750 and P01106 |
Pubmed |
SVM Score :0.0 |
| NA |
|