| Interacting proteins: P43246 and P01106 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P43246 and P01106 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P43246 and P01106 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P43246 and P01106 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P43246 and P01106 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P43246 and P01106 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P43246 and P01106 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P43246 and P01106 |
Pubmed |
SVM Score :0.0 |
| A novel MLH 1 mutation harbored as a germ line aberration by a young woman of an HNPCC like family and exhibited by a CML patient when occurring prior to the initiation of the blast phase concomitant with a c MYC amplification . ^^^ |
|
| Interacting proteins: P43246 and P01106 |
Pubmed |
SVM Score :0.0 |
| Increases occurred in oxidative stress responsive genes HO 1 , QR , HSP 70 , GADD 45 , GADD 153 , p 21 ( WAF1 / CIP16 ) , GST ' s , GAPDH , TPX , and GPX 1 ( 0 ) ; transcriptional regulators c jun , c fos , jun B , c myc , and IkappaB ; protein repair components Rdelta , RC 10 2 , C 3 , RC 7 , HR6B ubiquitin conjugating enzyme and ubiquitin ; DNA repair components PCNA , msh 2 , and O 6 methylguanine DNA methyltransferase ; lipid peroxide excision enzyme PLA 2 ; and apoptogenic components TNFalpha , iNOS 1 and FasL . ^^^ |
|
| Interacting proteins: P43246 and P01106 |
Pubmed |
SVM Score :0.0 |
| Interactions of the DNA mismatch repair proteins MLH 1 and MSH 2 with c MYC and MAX . ^^^ We further demonstrate that the heterodimeric partner of c MYC , MAX , interacts with a different MMR protein , MSH 2 , both in vitro and in vivo . ^^^ |
|
| Interacting proteins: P43246 and P01106 |
Pubmed |
SVM Score :0.0 |
| Myc down regulation sensitizes melanoma cells to radiotherapy by inhibiting MLH 1 and MSH 2 mismatch repair proteins . ^^^ CONCLUSIONS : Data herein reported show that Myc down regulation lowers the apoptotic threshold in melanoma cells by inhibiting MLH 1 and MSH 2 proteins , thus increasing cell sensitivity to gamma radiation in a p 53 independent fashion . ^^^ |
|
| Interacting proteins: P43246 and P01106 |
Pubmed |
SVM Score :0.0 |
| Interestingly , when overlapping genes were excluded , 12 ( e . g . , NM 23 H2 , MCM 7 , PARP 1 , YWHAH , HSPB 1 , and MSH 2 ) of the top 34 upregulated genes and five ( e . g . , MT1A and MT 3 ) of the top 33 downregulated genes were c myc regulated genes . ^^^ |
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