| Interacting proteins: P19784 and P01106 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P19784 and P01106 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P19784 and P01106 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P19784 and P01106 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P19784 and P01106 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P19784 and P01106 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P19784 and P01106 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P19784 and P01106 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P19784 and P01106 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P19784 and P01106 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P19784 and P01106 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P19784 and P01106 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P19784 and P01106 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P19784 and P01106 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P19784 and P01106 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P19784 and P01106 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P19784 and P01106 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P19784 and P01106 |
Pubmed |
SVM Score :0.0 |
| Since a number of potential nuclear CK 2 targets have been reported , including the oncoprotein myc , it is suggested that the nuclear translocation of the kinase as characterized in vitro may have a biological significance in living cell , especially in the control of nuclear activities related to cell proliferation and the mechanism of action of growth factors . . ^^^ |
|
| Interacting proteins: P19784 and P01106 |
Pubmed |
SVM Score :0.0 |
| CK 2 cooperates in transforming cells with other lymphoid oncogenes such as myc and tal 1 , and here we show cooperativity with loss of the tumor suppressor gene p 53 . ^^^ |
|
| Interacting proteins: P19784 and P01106 |
Pubmed |
SVM Score :0.0 |
| Functional interaction of protein kinase CK 2 and c Myc in lymphomagenesis . ^^^ Since c myc can be phosphorylated by CK 2 , we hypothesized that the synergy between CK 2 and c myc might be due to a functional interaction of the two molecules . ^^^ Pharmacologic inhibition of CK 2 activity in cell lines established from CK2alpha transgenic T cell lymphomas reduces their proliferation and concomitantly with this , the steady state levels of c myc protein decline . ^^^ Transfection of cells with sense or anti sense CK 2 constructs modulates c myc protein levels in concert with the alteration in CK 2 activity , validating the findings obtained using the kinase inhibitors . ^^^ Thus , CK 2 is a critical regulator of c myc protein stability and of the proliferation of these T cell lymphomas . . ^^^ |
|
| Interacting proteins: P19784 and P01106 |
Pubmed |
SVM Score :0.0 |
| Activation of casein kinase 2 ( CK 2 ) was one of the first observations made on how Theileria parasites manipulate host cell signal transduction pathways and we argue that CK 2 induction may in fact contribute to many of the different activation events that have been described since 1993 for Theileria infected lymphocytes such as sustained activation of transcription factors c Myc and NF kappaB . ^^^ |
|