Interacting proteins: P19338 and P01106 |
Pubmed |
SVM Score :0.0 |
Both nucleolin and hsp 70 mRNA began to increase simultaneously after peaks of c fos and c myc , showed a peak 6 h after partial hepatectomy , and declined to the control levels around 20 h . ^^^ |
|
Interacting proteins: P19338 and P01106 |
Pubmed |
SVM Score :0.0 |
Myc induces the nucleolin and BN 51 genes : possible implications in ribosome biogenesis . ^^^ |
|
Interacting proteins: P19338 and P01106 |
Pubmed |
SVM Score :0.0 |
Identified targets possibly linked to MYC ' s effects on cell growth include the nucleolar proteins nucleolin and fibrillarin , as well as the eukaryotic initiation factor 5A . ^^^ |
|
Interacting proteins: P19338 and P01106 |
Pubmed |
SVM Score :0.0 |
Interestingly , comparing our results with other high throughput screens reveals that certain putative Myc targets previously reported are shown not to be regulated downstream of Myc ( e . g . ribosomal proteins , HSP90beta ) , whereas others are further supported by our analyses ( e . g . pdgfbetar , nucleolin ) . ^^^ |
|
Interacting proteins: P19338 and P01106 |
Pubmed |
SVM Score :0.0 |
Although the majority of target genes studied [ class 1 : B 23 ( NPM 1 ) , CAD , CDK 4 , cyclin D 2 , ID 2 , LDH A , MNT , PTMa , ODC , NM23B , nucleolin , prohibitin , SHMT 1 , and SHMT 2 ] demonstrate significant sequence conservation of the E boxes and flanking regions , several genes ( cyclin B 1 , JPO 1 , and PRDX 3 ) belong to a second class ( class 2 ) that does not display sequence conservation at and around the site of c Myc binding . ^^^ |
|
Interacting proteins: P19338 and P01106 |
Pubmed |
SVM Score :0.0 |
These observations prompted us to examine the expression profile of the c Myc target genes , carbamoyl phosphate synthase aspartate carbamoyltransferase dihydroorotase ( cad ) and nucleolin ( nuc ) . ^^^ |
|
Interacting proteins: P19338 and P01106 |
Pubmed |
SVM Score :0.0 |
Both full length and truncated versions of nucleolin were tagged at their amino termini with five tandem human c myc epitopes . ^^^ |
|
Interacting proteins: P19338 and P01106 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: P19338 and P01106 |
Pubmed |
SVM Score :0.0 |
NA |
|