| Interacting proteins: P15336 and P01106 |
Pubmed |
SVM Score :0.0 |
| Crosstalk between Myc and activating transcription factor 2 ( ATF 2 ) : Myc prolongs the half life and induces phosphorylation of ATF 2 . ^^^ In this work we present evidence that 5 Myc encoded by the avian retrovirus MC 29 stimulates activating transcription factor 2 ( ATF 2 ) dependent transcription . ^^^ |
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| Interacting proteins: P15336 and P01106 |
Pubmed |
SVM Score :0.0 |
| Incubation of VSMC with ouabain resulted in rapid induction of c Fos protein expression with an approximately sixfold elevation after 2 h of incubation . c Jun expression was increased by approximately fourfold after 12 h , whereas expression of activating transcription factor 2 , cAMP / Ca ( 2+ ) response element binding protein ( CREB ) 1 and c Myc was not altered . ^^^ |
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| Interacting proteins: P15336 and P01106 |
Pubmed |
SVM Score :0.0 |
| No changes were observed , however , in the DNA binding activity of ATF 2 and Elk 1 , transcription factors involved in both the JNK and p 38 pathways of MAP signal transduction , nor in the gene expression of c myc . ^^^ |
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| Interacting proteins: P15336 and P01106 |
Pubmed |
SVM Score :0.0 |
| ATF 2 at Ser 69 / 71 , forming a complex with Myc for DNA binding at CRE motif ; 3 ) Max at Ser 62 to combine DNA of E Box motif . p 38 MAPK can be activated by LPS , inflammatory cytokines , such as TNF and IL 1 , osmolarity . ^^^ |
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| Interacting proteins: P15336 and P01106 |
Pubmed |
SVM Score :0.0 |
| Expression of active , phosphorylation dependent mitogen activated extracellular signal regulated kinases ( MAPK / ERKs ) , stress activated c Jun N terminal kinases ( SAPK / JNKs ) and p 38 kinases , as well as their putative active specific transcriptional factor substrates CREB , Elk 1 , ATF 2 , c Myc and c Jun , have been examined following intracortical injection of the glutamate analogue quinolinic acid ( QA ) . ^^^ In contrast , MAPK ( P ) , CREB ( P ) , Elk 1 ( P ) and ATF 2 ( P ) , but not phosphorylated c Myc ( c Myc ( P ) ) , over expression correlates with cell survival . ^^^ |
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| Interacting proteins: P15336 and P01106 |
Pubmed |
SVM Score :0.0 |
| Expression of active , phosphorylation dependent mitogen activated extracellular signal regulated kinases ( MAPK / ERKs ) , stress activated c Jun N terminal kinases ( SAPK / JNKs ) and p 38 kinases , as well as their putative active , phosphorylation dependent specific transcriptional factor substrates CREB , Elk 1 , ATF 2 , c Myc and c Jun , has been examined following systemic administration of kainic acid ( KA ) at convulsant doses to rats . ^^^ |
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| Interacting proteins: P15336 and P01106 |
Pubmed |
SVM Score :0.0 |
| Several MAPK regulated host transcription factors such as c Jun , STAT1alpha , MEF 2 , c Myc , ATF 2 and c Fos were induced early during infection , and ERK inhibition significantly blocked the c Fos , c Jun , c Myc , and STAT1alpha activation in the infected cells . ^^^ |
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| Interacting proteins: P15336 and P01106 |
Pubmed |
SVM Score :0.0 |
| These genes encode a host of proteins with divergent functions in a variety of cellular processes including apoptosis ( FAS , Fas ligand , PIN , HSP90beta , bcl 2 , bcl 10 ) , cell signal transduction ( Ras , RGS 1 , IRF 1 , STAT 3 ) , receptor mediated signaling transduction ( CD 71 , CD 69 , CD3delta ) , cell cycle and growth ( c myc , cytokines , kinase ) , transcriptional regulation ( EWS , CREB 2 ) , and chemotaxis ( beta chemokines , RANTES ) , supporting the general effects of HIV 1 infection on cells of different origin . ^^^ |
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| Interacting proteins: P15336 and P01106 |
Pubmed |
SVM Score :0.0 |
| The protein sequence deduced from the open reading frame of a human placental cDNA encoding a cAMP responsive enhancer ( CRE ) binding protein ( CREB 327 ) has structural features characteristic of several other transcriptional transactivator proteins including jun , fos , C / EBP , myc , and CRE BP 1 . ^^^ |
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| Interacting proteins: P15336 and P01106 |
Pubmed |
SVM Score :0.0 |
| Several molecules have been isolated by expression cloning , including CRE BP 1 associating with Jun ( Macgregor et al . , 1990 ) ; Grb 1 , identical to p 85 PI3 kinase , with the EGF receptor ( Skolnik et al . , 1991 ) ; and Max with Myc ( Blackwood and Eisenman , 1991 ) . ^^^ |
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| Interacting proteins: P15336 and P01106 |
Pubmed |
SVM Score :0.0 |
| By Western blot analysis using phospho specific antibodies against c Jun , ATF 2 , Elk 1 and c Myc we found increased phosphorylation of all these transcription factors in the myocardial risk area at the end of IP protocol and both local and systemic infusion of act D significantly ( P < 0 . 05 ) inhibited this increased phosphorylation . ^^^ |
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| Interacting proteins: P15336 and P01106 |
Pubmed |
SVM Score :0.0 |
| The expression of phosphorylation dependent , active transcription substrates of these kinases , including cyclic AMP responsive element binding protein ( CREB ) Alk 1 , ATF 2 , c Myc and c Jun was examined at early stages following reperfusion . ^^^ However , increased cytoplasmic expression of MAPK / ERK P , SAPK / JNK P , p 38 P , CREB P , Elk 1 P , c Myc P , ATF 2 P and c Jun P occurred in the region bordering the infarct core ( penumbra ) at 4 h following reperfusion . ^^^ |
|
| Interacting proteins: P15336 and P01106 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15336 and P01106 |
Pubmed |
SVM Score :0.0 |
| NA |
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