| Interacting proteins: P11388 and P01106 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P11388 and P01106 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P11388 and P01106 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P11388 and P01106 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P11388 and P01106 |
Pubmed |
SVM Score :0.0 |
| We characterized the cleavage complexes induced by the top 2 ( S740W ) in the human c myc gene . ^^^ |
|
| Interacting proteins: P11388 and P01106 |
Pubmed |
SVM Score :0.0 |
| A proliferating cell gene cluster included MET , VIM , MYC , TOP2A , PCNA , etc . ^^^ |
|
| Interacting proteins: P11388 and P01106 |
Pubmed |
SVM Score :0.0 |
| However , the IL 3 treatment coincided with an upregulation of DNA topoisomerase 2 alpha ( Topo 2 alpha ) at mRNA and protein level after 24 h , which was preceded by an upregulation of c myc mRNA . ^^^ |
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| Interacting proteins: P11388 and P01106 |
Pubmed |
SVM Score :0.0 |
| In this study we compared expression of DNA topoisomerase IIalpha , a marker of cellular proliferation , c myc , and cyclin D 1 in lung biopsy specimens showing diffuse alveolar damage ( DAD ) with control lung tissues . ^^^ We subsequently correlated DNA topoisomerase IIalpha , c myc , and cyclin D 1 expression with survival . ^^^ Immnuohistochemical stains for c myc , cyclin D 1 , and DNA topoisomerase IIalpha were performed on 10 cases of DAD ( 15 cases for DNA topoisomerase IIalpha ) and 10 control lungs . ^^^ |
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| Interacting proteins: P11388 and P01106 |
Pubmed |
SVM Score :0.0 |
| Promising approaches and molecular markers include gene expression profiles , DNA ploidy , loss of heterozygosity and chromosomal aberrations as detected by CGH and FISH ( 1q , 17p , 17q ) , as well as oncogenes / tumor suppressor genes and their proteins ( TP 53 , PTEN , c erbB 2 , N myc , c myc ) , growth factor and hormonal receptors ( PDGFRA , VEGF , EGFR , HER 2 , HER 4 , ErbB 2 , hTERT , TrkC ) , cell cycle genes ( p 27 ) and cell adhesion molecules , as well as factors potentially related to therapeutic resistance ( multi drug resistance , DNA topoisomerase IIalpha , metallothionein , P glycoprotein , tenascin ) . ^^^ |
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| Interacting proteins: P11388 and P01106 |
Pubmed |
SVM Score :0.0 |
| According to the known functions of their genes , the clusters were designated as proliferating cell ( CDC 42 , TOP2A , FGFR 3 , MYC , etc . ) , neoangiogenesis and blood cell ( LCK , VAV 1 , KDR , VEGF , MMP 9 , SYK , PTPRS , and FLT 4 ) , invasion 1 and invasion 2 ( ADAM 17 , TRPM 2 , DUSP 6 , VIM , CAV 1 , CAV 2 , JAK 1 , PTPNS 1 , FYN , and PDGFB ) , HER 2 , and PSA / PSM / HER3 . ^^^ |
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