| Interacting proteins: P01106 and P07900 |
Pubmed |
SVM Score :0.0 |
| Expression of the thyroid hormone receptor ( TR beta ) , the 90 KD heat shock protein ( HSP 90 ) , and the oncogenes H ras and c myc mRNA in normal hyperplastic , and neoplastic human thyroid tissue was investigated by Northern blot and slot blot analyses . ^^^ |
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| Interacting proteins: P01106 and P07900 |
Pubmed |
SVM Score :0.0 |
| Treatment of cultured human tumor cells with the chloroethylnitrosourea antitumor drug 1 , 3 bis ( 2 chloroethyl ) 1 nitrosourea ( BCNU ) selectively induces transcription and protein synthesis of a subset of the human heat shock or stress induced genes ( HSP 90 and HSP 70 ) with little effect on other stress genes or on expression of the c fos , c myc , or beta actin genes . ^^^ |
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| Interacting proteins: P01106 and P07900 |
Pubmed |
SVM Score :0.0 |
| The induction of the expression of two oncogenes ( c fos and c myc ) , three heat shock protein ( HSP ) genes ( HSP 27 , HSP 70 , and HSP 89 mRNAs ) and two antioxidative enzyme genes ( Mn superoxide dismutase ( SOD ) and catalase mRNAs ) by northern hybridisation , as well as the activities of four major antioxidative enzymes ( SOD , catalase , glutathione peroxidase , and glutathione reductase ) were examined in control and 1 10 PC and 4 10 PC hearts . ^^^ RESULTS : Northern hybridisation detected enhanced level of c fos 2 . 2 kb mRNA and c myc 2 . 4 kb mRNA in 4 10 PC hearts after 60 min of reperfusion , induction being stronger for c fos . 1 10 PC hearts showed minimal expression of c fos mRNA , but not c myc mRNA . 4 10 PC hearts also showed the induction of HSP 27 , HSP 70 , and HSP 89 mRNAs as well as catalase and Mn SOD mRNAs , whereas 1 10 PC hearts showed some induction of HSP 70 mRNA and catalase mRNA only . 2 D gel electrophoresis revealed the expression of 15 20 new proteins in 4 10 PC hearts only . ^^^ |
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| Interacting proteins: P01106 and P07900 |
Pubmed |
SVM Score :0.0 |
| It is the regulatory subunit of the DNA dependent protein kinase that phosphorylates many proteins , including SV 40 large T antigen , p 53 , RNA polymerase 2 , RP A , topoisomerases , hsp 90 , and many transcription factors such as c Jun , c Fos , oct 1 , sp 1 , c Myc , TFIID , and many more . ^^^ |
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| Interacting proteins: P01106 and P07900 |
Pubmed |
SVM Score :0.0 |
| Supershift assays identified the 90 kDa heat shock protein ( HSP 90 ) and c Myc as constituents of this DNA binding complex . ^^^ Coimmunoprecipitation studies confirmed the interaction between endogenous HSP 90 and c Myc . ^^^ This study provides evidence that the transcriptional up regulation of Cx 43 by Ras Raf MAPK is mediated via the interaction of a novel Cx 43 promoter element with a protein complex that contains both HSP 90 and c Myc . . ^^^ |
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| Interacting proteins: P01106 and P07900 |
Pubmed |
SVM Score :0.0 |
| Glioma : what is the role of c Myc , hsp 90 and telomerase . ^^^ The continuous advancements in cancer research have contributed to the overwhelming evidence of the presence of telomerase in primary and secondary tumours together with hsp 90 and c Myc . ^^^ This review will discuss the important role of telomerase together with hsp 90 and c Myc within the initiation and progression of gliomas . ^^^ |
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| Interacting proteins: P01106 and P07900 |
Pubmed |
SVM Score :0.0 |
| Also , a number of genes that are upregulated by c Myc in cells expressing wild type conformation p 53 encode chaperones related to cell death protection as HSP 105 , HSP 90 and HSP 27 . ^^^ |
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| Interacting proteins: P01106 and P07900 |
Pubmed |
SVM Score :0.0 |
| NA |
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| Interacting proteins: P01106 and P07900 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P01106 and P07900 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P01106 and P07900 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P01106 and P07900 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P01106 and P07900 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P01106 and P07900 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P01106 and P07900 |
Pubmed |
SVM Score :0.0 |
| NA |
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