| Interacting proteins: O75592 and P01106 |
Pubmed |
SVM Score :0.71973972 |
| Pam binds specifically to Myc , but not NMyc . 0.71973972^^^ |
|
| Interacting proteins: O75592 and P01106 |
Pubmed |
SVM Score :0.84126972 |
| These included mRNA encoding Pam , a protein associated with myc ; GRSF 1 , an mRNA binding protein involved in translation activation , and TRF 2 , a TATA box binding protein like protein involved in transcriptional regulation . 0.84126972^^^ |
|
| Interacting proteins: O75592 and P01106 |
Pubmed |
SVM Score :0.71643866 |
| Microarray gene screening reveals that quiescent and senescent cells , in comparison with replicating ones , are characterized by downregulation of Pam , a protein associated with c Myc , and upregulation of Mad family genes , Max dimerization proteins . 0.71643866^^^ |
|
| Interacting proteins: O75592 and P01106 |
Pubmed |
SVM Score :1.3019552 |
| We recently identified Pam ( for protein associated with c Myc ) , as a binding partner for the tuberous sclerosis complex ( TSC ) protein tuberin in brain . 1.3019552^^^ |
|
| Interacting proteins: O75592 and P01106 |
Pubmed |
SVM Score :0.0 |
| Protein associated with Myc ( PAM ) is a potent inhibitor of adenylyl cyclases . ^^^ Using the yeast two hybrid assay and the second of the two large cytosolic domains of type 5 adenylyl cyclase ( ACV ) as bait , we identified a small region ( amino acids 1028 1231 ) in the protein associated with Myc ( PAM ) as an interaction site for ACV . ^^^ |
|
| Interacting proteins: O75592 and P01106 |
Pubmed |
SVM Score :0.0 |
| Developmental expression of PAM ( protein associated with MYC ) in the rodent brain . ^^^ Recently , human protein associated with MYC , PAM , has been cloned and characterized as a large protein that interacts with the transcriptional activating domain of Myc . ^^^ |
|
| Interacting proteins: O75592 and P01106 |
Pubmed |
SVM Score :0.0 |
| The corresponding genes include carnitine palmitoyltransferase 1 , stromal cell derived factor 1 , a protein associated with MYC mRNA , basic transcription element binding protein , and expressed sequence tags ( ESTs ) of unknown function . ^^^ |
|
| Interacting proteins: O75592 and P01106 |
Pubmed |
SVM Score :0.0 |
| Two dimensional gel electrophoresis identified 13 different proteins migrating at 60 kDa ; 5 were splice variants of HSP 60 , and 2 corresponded with a protein associated with MYC ( PAM ) . ^^^ |
|
| Interacting proteins: O75592 and P01106 |
Pubmed |
SVM Score :0.0 |
| Phr 1 is the ortholog of the human Protein Associated with Myc as well as Drosophila highwire and Caenorhabditis elegans regulator of presynaptic morphology 1 . ^^^ |
|
| Interacting proteins: O75592 and P01106 |
Pubmed |
SVM Score :0.0 |
| Protein associated with Myc ( PAM ) is involved in spinal nociceptive processing . ^^^ PAM ( protein associated with Myc ) is a potent inhibitor of adenylyl cyclases ( ACs ) which is primarily expressed in neurones . ^^^ |
|
| Interacting proteins: O75592 and P01106 |
Pubmed |
SVM Score :0.0 |
| PAM ( Protein Associated with Myc ) is an almost ubiquitously expressed protein that is one of the most potent inhibitors of adenylyl cyclase activity known so far . ^^^ |
|
| Interacting proteins: O75592 and P01106 |
Pubmed |
SVM Score :0.0 |
| Histidine residues 912 and 913 in protein associated with Myc are necessary for the inhibition of adenylyl cyclase activity . ^^^ We reported previously that protein associated with Myc ( PAM ) interacts with the C 2 domain of type 5 adenylyl cyclase ( ACV C 2 ) and that purified PAM is a potent inhibitor of Galphas stimulated ACV activity ( J Biol Chem 276 : 47583 47589 , 2001 ) . ^^^ |
|
| Interacting proteins: O75592 and P01106 |
Pubmed |
SVM Score :0.0 |
| Formation of the retinotectal projection requires Esrom , an ortholog of PAM ( protein associated with Myc ) . ^^^ By positional cloning , we establish that esrom encodes a very large protein orthologous to PAM ( protein associated with Myc ) / Highwire / RPM 1 . ^^^ |
|
| Interacting proteins: O75592 and P01106 |
Pubmed |
SVM Score :0.0 |
| Novel regulators of AC 5 and AC 6 , including small molecules and proteins that physically interact with AC 5 and AC 6 such as snapin , regulator of G protein signaling 2 ( RGS 2 ) , protein associated with myc ( PAM ) , and caveolin peptides are discussed . ^^^ |
|
| Interacting proteins: O75592 and P01106 |
Pubmed |
SVM Score :0.0 |
| RPM 1 is most similar to the Drosophila presynaptic protein Highwire ( HIW ) and the mammalian Myc binding protein Pam . ^^^ |
|
| Interacting proteins: O75592 and P01106 |
Pubmed |
SVM Score :0.0 |
| Our unpublished work further documents the binding of tuberin with Pam , a protein associated with c Myc , which is enriched in brain . ^^^ |
|
| Interacting proteins: O75592 and P01106 |
Pubmed |
SVM Score :0.0 |
| We report here the association of Pam , a protein identified as an interactor of Myc , with the tuberin hamartin complex in the brain . ^^^ |
|
| Interacting proteins: O75592 and P01106 |
Pubmed |
SVM Score :0.0 |
| Esrom , an ortholog of PAM ( protein associated with c myc ) , regulates pteridine synthesis in the zebrafish . ^^^ Esrom has recently been identified as an ortholog of PAM ( protein associated with c myc ) , a very large protein involved in synaptogenesis in Drosophila and C . elegans . ^^^ |
|
| Interacting proteins: O75592 and P01106 |
Pubmed |
SVM Score :0.0 |
| NA |
|