| Interacting proteins: P15036 and P01100 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15036 and P01100 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15036 and P01100 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15036 and P01100 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15036 and P01100 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15036 and P01100 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15036 and P01100 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15036 and P01100 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15036 and P01100 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15036 and P01100 |
Pubmed |
SVM Score :0.0 |
| The upper or basal complex also includes c Fos , Fra 2 , Ets 2 , and Oct 1 . ^^^ |
|
| Interacting proteins: P15036 and P01100 |
Pubmed |
SVM Score :0.0 |
| When CSF 1R bearing cells expressing the Ets LacZ protein were stimulated by CSF 1 , induction of c ets 2 , c jun , and c fos ensued , but the c myc response was impaired . ^^^ |
|
| Interacting proteins: P15036 and P01100 |
Pubmed |
SVM Score :0.0 |
| Some members of the Ets family , Ets 1 and Ets 2 , cooperate in transcription with the AP 1 transcription factor , the product of the proto oncogene families , fos and jun , while others , Elk 1 and SAP 1 , form ternary complexes with the serum response factor ( SRF ) . ^^^ |
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| Interacting proteins: P15036 and P01100 |
Pubmed |
SVM Score :0.0 |
| Levels of fos , ets 2 , and myb proto oncogene RNAs correlate with segregation of chromosome 11 of normal cells and with suppression of tumorigenicity in human cell hybrids . ^^^ The only chromosome consistently segregated in the latter was chromosome 11 of the diploid cell . fos and ets 2 RNA levels and the amount of fos protein were consistently elevated in the segregants compared with amounts in the original hybrids . ^^^ Whether the genes affecting fos , ets 2 , and myb RNA levels are on chromosome 11 and whether these alterations are causally related to the tumorigenic phenotype of the hybrid remain to be determined . . ^^^ |
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| Interacting proteins: P15036 and P01100 |
Pubmed |
SVM Score :0.0 |
| Immunohistochemical analysis of the protein expression c myc , ets 1 , ets 2 , TPR met , c fos , c jun , c ras pan , p 53 , yes , src in 79 samples of normal , metaplastic squamous epithelium , intraepithelial and invasive squamous cell carcinoma of uterine cervix was performed using polyclonal rabbit antibodies to the synthetic peptides homologous active areas of corresponding oncoproteins . ^^^ Higher content of myc , fos , ets 2 , p 53 , ras is noted in metaplasia , dysplasia and in tumours as compared to the normal tissues . ^^^ Expression of the oncoproteins fos , ets 2 , p 53 , src in the metaplastic squamous cell carcinoma was higher than in the true squamous cell ( ectocervical ) carcinoma . ^^^ |
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| Interacting proteins: P15036 and P01100 |
Pubmed |
SVM Score :0.0 |
| Intriguingly , autonomous growth correlates with the suppression of CSF 1 mediated MAP Kinase activation and with the low constitutive expression of a number of CSF 1 inducible genes , including fos , jun , ets 2 , and myc , but also the genes for the inflammatory cytokines TNF alpha and IL 1 beta . ^^^ |
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| Interacting proteins: P15036 and P01100 |
Pubmed |
SVM Score :0.0 |
| Constitutive expression of c fos and c jun , overexpression of ets 2 , and reduced expression of metastasis suppressor gene nm 23 H1 in rheumatoid arthritis . ^^^ |
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| Interacting proteins: P15036 and P01100 |
Pubmed |
SVM Score :0.0 |
| However , the proteins ETS 1 , ETS 2 , PEA 3 and PU . 1 were unable to form ternary complexes with SRF on either the Egr 1 or c fos SREs . ^^^ This B box is not present in ETS 1 , ETS 2 , PEA 3 or PU . 1 and these proteins were unable to form ternary complexes with SRF and Egrl SREs or c fos SRE . ^^^ |
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| Interacting proteins: P15036 and P01100 |
Pubmed |
SVM Score :0.0 |
| We found that ETS 2 could weakly associate with in vitro synthesized ETS 1 , c Fos , and c Jun and strongly with c Fos / c Jun complex and ERG via several distinct ETS 2 domains including the C terminal region that contains the DNA binding domain . ^^^ The DNA dependent interaction of ETS 2 with c Fos / c Jun was enhanced by specific DNA fragments requiring two Ets binding sites of the stromelysin 1 promoter . ^^^ |
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| Interacting proteins: P15036 and P01100 |
Pubmed |
SVM Score :0.0 |
| We have also demonstrated that the expression of this Ets 2 mutant is capable of interrupting the CSF 1R regulated intracellular signaling pathways by inhibiting CSF 1 induced c myc , c fos , and c jun expression in BT 20 cells . ^^^ |
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| Interacting proteins: P15036 and P01100 |
Pubmed |
SVM Score :0.0 |
| Although other transcription factors like Fos , c Jun , Myc , STAT 3 , and STAT5a are implicated in the activation of macrophage competence or in CSF 1 signaling , no synergy was observed between Ets 2 and these transcription factors on the bcl 10 promoter . ^^^ |
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| Interacting proteins: P15036 and P01100 |
Pubmed |
SVM Score :0.0 |
| The oIFNtau gene promoter / enhancer ( 654 to + 1 bases , wild type ) luciferase reporter construct ( pGL 3 654 ) or its mutant at the AP 1 or Ets 2 site was cotransfected with CBP ( pRc / RSV CBP ) construct along with c jun , c fos , and / or Ets 2 expression plasmid . ^^^ Cotransfection of CBP with c jun and / or Ets 2 , but not with c fos , further increased oIFNtau gene transactivation although amounts of c jun and c fos expression , resulting from expression vectors , were similar . ^^^ |
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| Interacting proteins: P15036 and P01100 |
Pubmed |
SVM Score :0.0 |
| Moreover , cDNA array analysis of the gene expression profile in FRP treated arthritic lesions revealed a reduced expression of the c fos , ets 2 , IL 6 , MMP 3 , and MMP 9 genes , some of which are thought to be associated with synovial inflammation and joint destruction . ^^^ |
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| Interacting proteins: P15036 and P01100 |
Pubmed |
SVM Score :0.0 |
| A comparison of gene expression profiles of nontumorous transgenic liver versus control liver provided insight into the initial events predisposing liver cells to malignant transformation , and we found overexpression of c fos , eps 15 , TGIF , IGFBP 1 , Alcam , ets 2 and repression of Gas 1 as distinct events . ^^^ |
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