| Interacting proteins: P14921 and P01100 |
Pubmed |
SVM Score :0.0 |
| Some members of the Ets family , Ets 1 and Ets 2 , cooperate in transcription with the AP 1 transcription factor , the product of the proto oncogene families , fos and jun , while others , Elk 1 and SAP 1 , form ternary complexes with the serum response factor ( SRF ) . ^^^ |
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| Interacting proteins: P14921 and P01100 |
Pubmed |
SVM Score :0.0 |
| A 50 base pair sequence is sufficient to confer c Fos + c Jun and c Ets 1 responsiveness to a heterologous promoter . ^^^ |
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| Interacting proteins: P14921 and P01100 |
Pubmed |
SVM Score :0.0 |
| Coexpression of Ets 1 , Fos , Jun , or Myc with Myb did not increase trans activation of the mim 1 promoter . ^^^ |
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| Interacting proteins: P14921 and P01100 |
Pubmed |
SVM Score :0.0 |
| Functional analysis has shown that c jun enhances the activity of the ets 1 promoter , whereas the combination of c fos and c jun expressions has no synergistic effect . ^^^ |
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| Interacting proteins: P14921 and P01100 |
Pubmed |
SVM Score :0.0 |
| The p68c ets 1 protein cooperates with c Fos and c Jun ( components of AP 1 ) for activation of transcription from the oncogene responsive domain of the polyoma enhancer , indicating that combined activity of all three oncoproteins could be involved in the response of cells to growth stimuli . . ^^^ |
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| Interacting proteins: P14921 and P01100 |
Pubmed |
SVM Score :0.0 |
| Immunohistochemical analysis of the protein expression c myc , ets 1 , ets 2 , TPR met , c fos , c jun , c ras pan , p 53 , yes , src in 79 samples of normal , metaplastic squamous epithelium , intraepithelial and invasive squamous cell carcinoma of uterine cervix was performed using polyclonal rabbit antibodies to the synthetic peptides homologous active areas of corresponding oncoproteins . ^^^ |
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| Interacting proteins: P14921 and P01100 |
Pubmed |
SVM Score :0.0 |
| Furthermore , a complex of c Jun and c Fos interacted with c Ets 1 in vitro . ^^^ |
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| Interacting proteins: P14921 and P01100 |
Pubmed |
SVM Score :0.0 |
| To characterize the transcription factors in megakaryocytic cells that could bind to these two regulatory regions , we performed Northern blot analyses , which showed the presence of ets 1 , elf 1 ( which is thought to be restricted to T cells ) , NF IL3A and AML 1 mRNAs , as well as c fos , jun B , and jun D , but not c jun mRNA . ^^^ |
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| Interacting proteins: P14921 and P01100 |
Pubmed |
SVM Score :0.0 |
| However , the proteins ETS 1 , ETS 2 , PEA 3 and PU . 1 were unable to form ternary complexes with SRF on either the Egr 1 or c fos SREs . ^^^ This B box is not present in ETS 1 , ETS 2 , PEA 3 or PU . 1 and these proteins were unable to form ternary complexes with SRF and Egrl SREs or c fos SRE . ^^^ |
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| Interacting proteins: P14921 and P01100 |
Pubmed |
SVM Score :0.0 |
| We found that ETS 2 could weakly associate with in vitro synthesized ETS 1 , c Fos , and c Jun and strongly with c Fos / c Jun complex and ERG via several distinct ETS 2 domains including the C terminal region that contains the DNA binding domain . ^^^ |
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| Interacting proteins: P14921 and P01100 |
Pubmed |
SVM Score :0.0 |
| Northern analysis of ets 1 , a transcriptional activator of MMP 1 expression , showed that strain down regulated ets 1 expression , whereas c fos expression was augmented . ^^^ |
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| Interacting proteins: P14921 and P01100 |
Pubmed |
SVM Score :0.0 |
| PURPOSE : To detect the expression of mRNA of protooncogenes ets 1 , c jun , c fos , and platelet derived growth factor ( PDGF ) in proliferative membranes of patients with proliferative diabetic retinopathy ( PDR ) and proliferative vitreoretinopathy ( PVR ) . ^^^ Ets 1 , c jun , c fos , PDGF A , and PDGF B cDNA were amplified using reverse transcriptase polymerase chain reaction ( PCR ) . ^^^ CONCLUSIONS : Our results suggest that not only PDGF mRNA was expressed in the membranes of patients with PDR and PVR , but proto oncogenes ets 1 , c jun , and c fos mRNA were also expressed . . ^^^ |
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| Interacting proteins: P14921 and P01100 |
Pubmed |
SVM Score :0.0 |
| TNFalpha induces expression of transcription factors c fos , Egr 1 , and Ets 1 in vascular lesions through extracellular signal regulated kinases 1 / 2 . ^^^ Potential nuclear targets of TNFalpha activated ERK 1 / 2 include the transcription factors Ets 1 , Egr 1 , and c fos , which are known to regulate cellular growth , differentiation , and migration . ^^^ The aim of this study was to investigate the expression of the transcription factors Ets 1 , Egr 1 and c fos in different types of vascular lesions , their regulation by TNFalpha and the role of ERK 1 / 2 in these signaling events . ^^^ Atherosclerotic lesions from fructose fed LDL receptor deficient mice and neointimal lesions from rat aortae 2 weeks post balloon injury demonstrated the presence and colocalization of TNFalpha , phosphorylated and activated ERK 1 / 2 , and transcription factors Ets 1 , Egr 1 and c fos . ^^^ In cultured rat aortic VSMC , TNFalpha ( 100 U / ml ) stimulated a rapid and transient expression of Ets 1 , Egr 1 and c fos with a maximal induction 1 h after stimulation . ^^^ |
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| Interacting proteins: P14921 and P01100 |
Pubmed |
SVM Score :0.0 |
| Effect of EGCG , a major component of green tea , on the expression of Ets 1 , c Fos , and c Jun during angiogenesis in vitro . ^^^ In this study , we used rat aortic endothelial cells and human umbilical vein endothelial cells growing in collagen gel as a model system to study the tea catechin , ( ) epigallocatechin ( EGCG ) , on the differential expression of transcription factors , Ets 1 , c Fos , and c Jun during endothelial morphogenesis in vitro . ^^^ Immunohistochemistry and immunofluorescence microscopy showed that the reaction products of Ets 1 , c Fos , and c Jun presented predominantly in the nucleus . ^^^ Western blotting showed that the levels of Ets 1 , c Fos , and c Jun reached the highest levels at 12 24 h , decreasing to the basal level at 48 h . ^^^ These results indicated that the morphogenesis of endothelial cells in collagen gel was inhibited by EGCG through the down regulation of Ets 1 , c Fos , and c Jun . . ^^^ |
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| Interacting proteins: P14921 and P01100 |
Pubmed |
SVM Score :0.0 |
| A down regulation of c jun , NF kappaB 1 , Max , Ets 1 , and p 53 mRNA , and an up regulation of c fos mRNA was noticed . ^^^ |
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| Interacting proteins: P14921 and P01100 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14921 and P01100 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14921 and P01100 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14921 and P01100 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14921 and P01100 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14921 and P01100 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14921 and P01100 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14921 and P01100 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14921 and P01100 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14921 and P01100 |
Pubmed |
SVM Score :0.0 |
| NA |
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