| Interacting proteins: P04920 and P00918 |
Pubmed |
SVM Score :0.0 |
| Carbonic anhydrase 2 ( CA 2 ) was expressed at higher abundance in the surface mucous cells and mucous neck cells , which expressed NHE 1 , than in the parietal cells , which expressed AE 2 . ^^^ The morphological evidence identified AE 2 as a major parietal cell anion exchanger , whereas NHE 1 and CA 2 colocalized in mucous neck , chief , and surface mucous cells . ^^^ Carbonic anhydrase 2 ( CA 2 ) was expressed at higher abundance in the surface mucous cells and mucous neck cells , which expressed NHE 1 , than in the parietal cells , which expressed AE 2 . ^^^ |
|
| Interacting proteins: P04920 and P00918 |
Pubmed |
SVM Score :0.0 |
| A GST Ct construct mutated to D887ANE , the homologous sequence in AE 2 , could bind CAII . ^^^ A GST fusion protein of the 33 residue Ct of AE 2 could bind to CAII similarly to the Ct of AE 1 . ^^^ |
|
| Interacting proteins: P04920 and P00918 |
Pubmed |
SVM Score :0.0 |
| A similar effect of V143Y CAII was found for AE 2 and AE3cardiac anion exchanger isoforms . ^^^ |
|
| Interacting proteins: P04920 and P00918 |
Pubmed |
SVM Score :0.0 |
| Expression of the inactive CAII V143Y mutant blocked the interaction between endogenous cytosolic CAII and AE 1 , AE 2 , and AE 3 and inhibited their transport activity ( 53 + / 3 , 49 + / 10 , and 35 + / 1 % inhibition , respectively ) . ^^^ However , in the presence of V143Y CAII , expression of CAIV restored full functional activity to AE 1 , AE 2 , and AE 3 ( AE 1 , 101 + / 3 ; AE 2 , 85 + / 5 ; AE 3 , 108 + / 1 % ) . ^^^ |
|
| Interacting proteins: P04920 and P00918 |
Pubmed |
SVM Score :0.0 |
| It is concluded that chloride enters the basolateral aspect of the cells using the Na+ K+ 2Cl cotransporter and a parallel arrangement of NHE 1 with AE 2 , these latter two being sensitive to acetazolamide because of their association with the cytoplasmic form of carbonic anhydrase CAII . ^^^ |
|
| Interacting proteins: P04920 and P00918 |
Pubmed |
SVM Score :0.0 |
| Bicarbonate secretion by rat bile duct brush cells indicated by immunohistochemical localization of CFTR , anion exchanger AE 2 , Na+ / HCO3 cotransporter , carbonic anhydrase 2 , Na+ / H+ exchangers NHE 1 and NHE 3 , H+ / K+ ATPase , and Na+ / K+ ATPase . ^^^ |
|
| Interacting proteins: P04920 and P00918 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04920 and P00918 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04920 and P00918 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04920 and P00918 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04920 and P00918 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04920 and P00918 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04920 and P00918 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04920 and P00918 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04920 and P00918 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04920 and P00918 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04920 and P00918 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04920 and P00918 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04920 and P00918 |
Pubmed |
SVM Score :0.0 |
| NA |
|