| Interacting proteins: P00749 and P00734 |
Pubmed |
SVM Score :0.0 |
| Arterial and coronary sinus blood were sampled concomitantly before cardioplegia and after release of the aortic cross clamp , for measurement of t PA antigen ( Ag ) and activity , plasminogen activator inhibitor ( PAI 1 ) Ag and activity , t PA / PAI 1 complex , single chain urokinase ( sc uPA ) and urokinase ( uPA ) plasminogen activators , the fibrin split product D dimer , thrombin antithrombin complex ( TAT ) , and the prothrombin split product F 1 + 2 . ^^^ |
|
| Interacting proteins: P00749 and P00734 |
Pubmed |
SVM Score :0.0 |
| In 15 patients we investigated coagulation parameters before , during and post CPB , i . e . , fibrinogen , antithrombin ( AT ) 3 , thrombin antithrombin complex ( TAT ) , prothrombin fragments F 1 + 2 ( F 1 + 2 ) , factor ( F ) XIIa , tissue factor ( TF ) , and parameters of the fibrinolytic system , i . e . , plasmin antiplasmin complex ( PAP ) , D dimer , tissue plasminogen activator ( tPA ) , urokinase type plasminogen activator ( uPA ) , and plasminogen activator inhibitor type 1 ( PAI 1 ) . ^^^ |
|
| Interacting proteins: P00749 and P00734 |
Pubmed |
SVM Score :0.0 |
| Multivariate Cox analysis performed to correct these results for relative impact of the uPA system and established prognostic factors showed PAI 1 ( disease free survival : P=0 . 002 , relative risk 1 . 86 ; overall survival : P=0 . 005 , relative risk 1 . 39 ) , pT and pN as independent parameters . ^^^ |
|
| Interacting proteins: P00749 and P00734 |
Pubmed |
SVM Score :0.0 |
| Median levels of both uPA and PAI 1 showed significant correlation with tumor pT , pN , and pM categories , whereas the presence of lymphatic invasion correlated only with the uPA content and tumor grade correlated only with PAI 1 content . ^^^ By univariate analysis , depth of tumor invasion ( pT ) , lymph node involvement ( pN ) , number of involved lymph nodes , lymph node ratio , distant nodal metastases [ pM 1 ( Iym ) ] , lymphatic invasion , and uPA showed significant correlations with patient survival . ^^^ |
|
| Interacting proteins: P00749 and P00734 |
Pubmed |
SVM Score :0.0 |
| No significant correlation could be shown between the different patterns of uPA expression and various clinicopathological parameters , such as pT category , pN category , tumor size , histological grade , blood vessel invasion , lymphatic vessel invasion , and inflammatory response . ^^^ |
|
| Interacting proteins: P00749 and P00734 |
Pubmed |
SVM Score :0.0 |
| However , higher hypercoagulation evidenced by significantly raised prothrombin formation and clot elasticity together with higher levels of D dimer , uPA antigen and PAI 1 than observed in normal pregnancy suggests a hyperfibrinolytic / inhibitor state in hydrops fetalis pregnancy associated with bad obstetric outcome . ^^^ |
|
| Interacting proteins: P00749 and P00734 |
Pubmed |
SVM Score :0.0 |
| We have recently shown that either exogenous or endogenous , transfected OPN induces both uPA expression and increased invasiveness of 21 PT ( non tumorigenic ) and 21 NT ( tumorigenic ) human mammary epithelial cells . ^^^ |
|
| Interacting proteins: P00749 and P00734 |
Pubmed |
SVM Score :0.0 |
| OBJECTIVES : To measure the plasma levels of urokinase plasminogen activator ( uPA ) , urokinase plasminogen activator receptor ( uPAR ) and plasminogen activator inhibitor 1 ( PAI 1 ) , and study the relationship between the plasma levels of uPA , PAI 1 and the serum albumin ( Alb ) , collagen type 4 ( CIV ) , the serum hyaluronic acid ( HA ) , prothrombin time ( PT ) and prothrombin activity ( PTA ) in patients with different stages of liver cirrhosis following chronic hepatitis B . ^^^ |
|
| Interacting proteins: P00749 and P00734 |
Pubmed |
SVM Score :0.0 |
| Plasma levels of fibrinopeptide A ( FPA ) , fibrin d dimer , thrombin antithrombin ( TAT ) complex , prothrombin fragment 1 . 2 ( F1 . 2 ) , urokinase type plasminogen activator ( uPA ) , tissue type plasminogen activator ( t PA ) and plasminogen activator inhibitor 1 ( PAI 1 ) were measured before and after therapy , as was the cellular expression of the genes for tissue factor ( TF ) and interleukin 1 beta ( IL 1 beta ) . ^^^ |
|
| Interacting proteins: P00749 and P00734 |
Pubmed |
SVM Score :0.0 |
| Cox ' s univariate analysis showed that pT ( p = 0 . 0007 ) , uPA ( p = 0 . 0156 ) and PAI 1 ( p = 0 . 0015 ) had a significant impact on relapse free survival , whereas VEGF did not have any prognostic value ( p = 0 . 18 ) . ^^^ |
|
| Interacting proteins: P00749 and P00734 |
Pubmed |
SVM Score :0.0 |
| Plasma D dimers ( one ELISA and two latex assays ) , fibrin monomer , prothrombin fragment 1 + 2 ( F1+2 ) , thrombin antithrombin 3 complex ( TAT ) and the t PA PAI 1 complex were all significantly correlated to the extension of DVT , whilst fibronectin , tissue type plasminogen activator ( t PA ) , single chain urokinase type plasminogen activator ( scru PA ) and plasminogen activator inhibitor 1 ( PAI 1 ) were not . ^^^ |
|
| Interacting proteins: P00749 and P00734 |
Pubmed |
SVM Score :0.0 |
| Plasma samples for prothrombin fragment 1+2 , thrombin antithrombin 3 complex , plasmin alpha 2 antiplasmin complex , tissue type plasminogen activator antigen , urokinase type plasminogen activator antigen , u PA activity , plasminogen activity , alpha 2 antiplasmin and alpha 2 macroglobulin assays were obtained from AVF and contralateral large veins of ESRD patients and from peripheral veins of the control group . ^^^ |
|
| Interacting proteins: P00749 and P00734 |
Pubmed |
SVM Score :0.0 |
| Components of the coagulation ( thrombin antithrombin complexes , prothrombin fragment F 1 + 2 , activated factor 7 , and factor 7 antigen ) and fibrinolytic ( fibrin split product D dimer , plasmin plasmin inhibitor complex , tissue type plasminogen activator , urokinase type plasminogen activator , and plasminogen activator inhibitor 1 ) systems and markers of endothelial cell perturbation / dysfunction ( von Willebrand factor and thrombomodulin ) were measured before the start of infusion and after 2 , 6 , 12 , and 24 hours . ^^^ |
|
| Interacting proteins: P00749 and P00734 |
Pubmed |
SVM Score :0.0 |
| METHODS : We studied seven variables of the coagulation pathway ( PT , aPTT , fibrinogen , FVIII : c , von Willebrand factor , thrombin antithrombin complexes , prothrombin fragments 1+2 ) and seven parameters of the fibrinolytic system ( plasminogen , alpha 2 antiplasmin , C 1 esterase inhibitor , tissue type plasminogen activator , urokinase type plasminogen activator , plasminogen activator inhibitor type 1 , D dimer ) in 24 pediatric patients with diarrhea associated hemolytic uremic syndrome and in 15 children with acute renal failure not due to hemolytic uremic syndrome . ^^^ |
|
| Interacting proteins: P00749 and P00734 |
Pubmed |
SVM Score :0.0 |
| In total , 22 functional and immunologic assays were applied to plasma obtained from domestic pigs , and the following blood coagulation and fibrinolysis variables were measured : prothrombin time , activated partial thromboplastin time , tissue factor , tissue factor pathway inhibitor , factor 7 , protein C , protein S , prothrombin fragment 1+2 , antithrombin , thrombin antithrombin complexes , fibrinogen , soluble fibrin , urokinase type plasminogen activator , plasmin inhibitor , plasminogen activator inhibitor 1 , and D dimer . ^^^ |
|
| Interacting proteins: P00749 and P00734 |
Pubmed |
SVM Score :0.0 |
| We also measured D dimer , lipid pattern , soluble E selectin , platelet surface P selectin , prothrombin fragments 1 + 2 ( F 1 + 2 ) , lipoprotein ( a ) , factor 7 , von Willebrand factor , plasma insulin , fibrinogen , homocysteine , thrombin activable fibrinolysis inhibitor ( TAFI ) activity , thrombomodulin , factor 13 , urokinase type plasminogen activator . ^^^ |
|
| Interacting proteins: P00749 and P00734 |
Pubmed |
SVM Score :0.0 |
| The study also revealed that tetranectin did not interact with the kindred proteins : macrophage stimulating protein , urokinase type plasminogen activator and prothrombin . ^^^ |
|
| Interacting proteins: P00749 and P00734 |
Pubmed |
SVM Score :0.0 |
| Plasma levels of the thrombin activation system ( thrombin antithrombin complex [ TAT ] , tissue factor pathway inhibitor [ TFPI ] , and prothrombin fragments 1+2 [ F1+2 ] ) and plasmin activation system ( tissue and urokinase type plasminogen activator [ t PA and u PA ] , plasminogen activator inhibitor 1 [ PAI 1 ] , and D dimer ) were measured with enzyme linked immunosorbent assay kits before angiography . ^^^ |
|
| Interacting proteins: P00749 and P00734 |
Pubmed |
SVM Score :0.0 |
| METHODS : Serial bronchoalveolar lavage fluid ( BALF ) samples were assayed for prothrombin activation fragment ( F1+2 ) , thrombin antithrombin ( TAT ) complex , fibrinolytic activity , urokinase type plasminogen activator ( u PA ) , and plasminogen activator inhibitor type 1 ( PAI 1 ) on days 1 , 4 , and 7 after VAP onset . ^^^ |
|
| Interacting proteins: P00749 and P00734 |
Pubmed |
SVM Score :0.0 |
| RESULTS : Patients in group 1 were characterized by increased factor VIIa levels , increased prothrombin fragment 1+2 levels , reduced factor XIIa levels , diminished functional urokinase type plasminogen activator levels , and decreased levels of plasmin / alpha 2 plasmin inhibitor complexes . ^^^ |
|
| Interacting proteins: P00749 and P00734 |
Pubmed |
SVM Score :0.0 |
| To investigate possible haematologic side effects of ATF , measurements of haemoglobin , haematocrit , fibrinogen concentration , thrombin , prothrombin and partial thromboplastin time , antithrombin 3 and fibrinolytic activity were made in all patients preoperatively and on postoperative days 1 and 2 . ^^^ |
|
| Interacting proteins: P00749 and P00734 |
Pubmed |
SVM Score :0.0 |
| To investigate the pathogenetic mechanisms of tubule nephrotoxicity of low molecular weight proteins ( LMWP ) , proximal tubules ( PT ) of rats were perfused in vivo with artificial tubule fluid ( ATF ) containing one of five LMWPs : three human Bence Jones proteins ( BJP ) , beta lactoglobulin ( BLG ) , and rabbit myoglobin ( MYG ) . ^^^ |
|
| Interacting proteins: P00749 and P00734 |
Pubmed |
SVM Score :0.0 |
| ATF is formulated from the prothrombin time ( PT ) , fibrinogen transformation rate ( FTR ) ( a representation of thrombin activity ) , and a consideration of the fibrinogen ( FBG ) content of blood plasma . ^^^ The ATF is independent of the Tp used , and , although Tp affects the PTs , Tp essentially only initiates the tissue factor pathway ( TFP ) ( extrinsic clotting system ) to then obtain the PT . ^^^ |
|
| Interacting proteins: P00749 and P00734 |
Pubmed |
SVM Score :0.0 |
| To study the effects of methylarginines on tubuloglomerular feedback ( TGF ) response , vehicle or methylarginines ( 10 ( 3 ) M ) were added to artificial tubular fluid ( ATF ) perfused orthogradely from the late PT at 40 nl . min 1 while assessing changes in glomerular capillary pressure from proximal stop flow pressure ( PSF ) . ^^^ |
|
| Interacting proteins: P00749 and P00734 |
Pubmed |
SVM Score :0.0 |
| In the present study , all patients were on warfarin therapy for at least six weeks , and the ATF equation was modified by multiplying it by the prothrombin ratio ( PR ) to give a corrected ATF ( CATF ) . ^^^ |
|
| Interacting proteins: P00749 and P00734 |
Pubmed |
SVM Score :0.0 |
| In this study , the ATF was modified to an MATF by both multiplying the ATF by the prothrombin ratio ( PR ) and adjusting the INR ATF linear regression analysis line by analytic geometry , so that the slope was one and the line passed through the origin . ^^^ |
|
| Interacting proteins: P00749 and P00734 |
Pubmed |
SVM Score :0.0 |
| Significant correlations were found between u PA plasma levels and the results of seven different liver function tests in three groups without associated HCC ; u PA antigen and prothrombin time ( % ) , hepaplastin test ( % ) , serum cholinesterase , serum albumin , serum total cholesterol , and indocyanine green clearance correlated negatively , while u PA antigen and serum total bilirubin correlated positively . ^^^ |
|
| Interacting proteins: P00749 and P00734 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P00749 and P00734 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P00749 and P00734 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P00749 and P00734 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P00749 and P00734 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P00749 and P00734 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P00749 and P00734 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P00749 and P00734 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P00749 and P00734 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P00749 and P00734 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P00749 and P00734 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P00749 and P00734 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P00749 and P00734 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P00749 and P00734 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P00749 and P00734 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P00749 and P00734 |
Pubmed |
SVM Score :0.0 |
| NA |
|