| Interacting proteins: P30044 and P00441 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P30044 and P00441 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P30044 and P00441 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P30044 and P00441 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P30044 and P00441 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P30044 and P00441 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P30044 and P00441 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P30044 and P00441 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P30044 and P00441 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P30044 and P00441 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P30044 and P00441 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P30044 and P00441 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P30044 and P00441 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P30044 and P00441 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P30044 and P00441 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P30044 and P00441 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P30044 and P00441 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P30044 and P00441 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P30044 and P00441 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P30044 and P00441 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P30044 and P00441 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P30044 and P00441 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P30044 and P00441 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P30044 and P00441 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P30044 and P00441 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P30044 and P00441 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P30044 and P00441 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P30044 and P00441 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P30044 and P00441 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P30044 and P00441 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P30044 and P00441 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P30044 and P00441 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P30044 and P00441 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P30044 and P00441 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P30044 and P00441 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P30044 and P00441 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P30044 and P00441 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P30044 and P00441 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P30044 and P00441 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P30044 and P00441 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P30044 and P00441 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P30044 and P00441 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P30044 and P00441 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P30044 and P00441 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P30044 and P00441 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P30044 and P00441 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P30044 and P00441 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P30044 and P00441 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P30044 and P00441 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P30044 and P00441 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P30044 and P00441 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P30044 and P00441 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P30044 and P00441 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P30044 and P00441 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P30044 and P00441 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P30044 and P00441 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P30044 and P00441 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P30044 and P00441 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P30044 and P00441 |
Pubmed |
SVM Score :0.0 |
| The structure is a homodimer and reveals a fold typical for beta family PLP dependent enzymes . ^^^ |
|
| Interacting proteins: P30044 and P00441 |
Pubmed |
SVM Score :0.0 |
| ACR 1 contains a bZIP domain that is necessary for homodimer formation and specific DNA binding to an ATF / CREB site . ^^^ |
|
| Interacting proteins: P30044 and P00441 |
Pubmed |
SVM Score :0.0 |
| In accord with the properties of the fern enzyme , the Streptomyces enzyme is also a homodimer of Mr 100 , 000 + / 5000 and requires PLP for activity . ^^^ |
|
| Interacting proteins: P30044 and P00441 |
Pubmed |
SVM Score :0.0 |
| The present study was undertaken to characterize the pyridoxal 5 ' phosphate ( PLP ) binding to a recombinant rat serine : pyruvate / alanine : glyoxylate aminotransferase ( SPT 10 ) , which is a homodimer of 44 . 4 kDa subunits . ^^^ |
|
| Interacting proteins: P30044 and P00441 |
Pubmed |
SVM Score :0.0 |
| The gene product was a homodimer with the subunit Mr of 44 , 439 , contained 1 mol of PLP as a cofactor per mol of subunit , and catalyzed the release of Se , SO 2 , and S from L selenocysteine , L cysteine sulfinic acid , and L cysteine , respectively , to yield L alanine ; the reactivity of the substrates decreased in this order . ^^^ |
|
| Interacting proteins: P30044 and P00441 |
Pubmed |
SVM Score :0.0 |
| ODC is a pyridoxal 5 ' phosphate ( PLP ) dependent enzyme and an obligate homodimer . 10 ray structural analysis of the complex of the T . brucei wild type enzyme with the product putrescine reveals two structural changes that occur upon ligand binding : Lys 69 is displaced by putrescine and forms new interactions with Glu 94 and Asp 88 , and the side chain of Cys 360 rotates into the active site to within 3 . 4 A of the imine bond . ^^^ |
|
| Interacting proteins: P30044 and P00441 |
Pubmed |
SVM Score :0.0 |
| Using two dimensional gel electrophoresis ( 2 DE ) and Western blot analysis , we were able to identify and quantify six antioxidant proteins , peroxiredoxin ( Prx ) 1 , Prx 2 , Prx 3 , 1 Cys Prx , putative peroxisomal antioxidant enzyme ( PLP ) , and mitochondrial Mn superoxide dismutase ( Mn SOD ) in two individual brain regions , cerebellum and frontal cortex of patients with sporadic Creutzfeldt Jacob ( sCJD ) . ^^^ |
|
| Interacting proteins: P30044 and P00441 |
Pubmed |
SVM Score :0.0 |
| The enzyme is a homodimer with one pyridoxal 5 ' phosphate ( PLP ) bound per subunit deep within the protein in a cleft between the N and C terminal domains of each of the monomers . ^^^ |
|
| Interacting proteins: P30044 and P00441 |
Pubmed |
SVM Score :0.0 |
| The enzyme is a thermostable homodimer ( 32 kDa / monomer ) belonging to the beta family of pyridoxal phosphate ( PLP ) dependent enzymes . ^^^ |
|
| Interacting proteins: P30044 and P00441 |
Pubmed |
SVM Score :0.0 |
| The structure of the protein reveals a homodimer adopting the fold type 1 of pyridoxal 5 ' phosphate ( PLP ) dependent aminotransferases . ^^^ |
|
| Interacting proteins: P30044 and P00441 |
Pubmed |
SVM Score :0.0 |
| The enzyme is a homodimer and requires PLP and divalent cations , Ca2+ , Mg2+ , Mn2+ , Fe2+ , or Ni2+ , at alkaline pH for both activities . ^^^ |
|
| Interacting proteins: P30044 and P00441 |
Pubmed |
SVM Score :0.0 |
| A comparative study of the antioxidant enzymes superoxide dismutase , catalase , glutathione reductase and thioredoxin reductase was undertaken in two families with xeroderma pigmentosum ( XP ) and in healthy controls of corresponding skin phototypes . ^^^ Epidermal blister roofs obtained from the XP patients revealed significant decreases in catalase , thioredoxin reductase , and superoxide dismutase , but glutathione reductase was unaffected . ^^^ |
|
| Interacting proteins: P30044 and P00441 |
Pubmed |
SVM Score :0.0 |
| Levels of thioredoxin reductase ( TR ) , glutathione reductase ( GR ) , superoxide dismutase ( SOD ) , and catalase ( CAT ) were determined in S91 / amel and S91 / I3 . ^^^ |
|
| Interacting proteins: P30044 and P00441 |
Pubmed |
SVM Score :0.0 |
| Stress , catecholamines ( CA ) , cAMP and protein kinase A do not affect superoxide dismutase , catalase , thioredoxin reductase , thiol transferase and glutathione reductase ( GR ) . ^^^ |
|
| Interacting proteins: P30044 and P00441 |
Pubmed |
SVM Score :0.0 |
| During the course of pigmentation , the expression of thioredoxin reductase was increased , whereas for the other antioxidant enzymes , superoxide dismutase ( cytosol Cu / Zn enzyme ) , catalase , and glutathione reductase , levels and activities decreased . ^^^ |
|
| Interacting proteins: P30044 and P00441 |
Pubmed |
SVM Score :0.0 |
| There is a slower spontaneous conversion of Trx to a homodimer that is not a substrate for reduction by thioredoxin reductase and that does not stimulate cell proliferation . ^^^ |
|
| Interacting proteins: P30044 and P00441 |
Pubmed |
SVM Score :0.0 |
| In line with these findings , we also report that the production of recombinant Xenopus laevis Cu , Zn superoxide dismutase is enhanced when the enzyme is exported in the periplasmic space or is expressed in thioredoxin reductase mutant strains . ^^^ |
|
| Interacting proteins: P30044 and P00441 |
Pubmed |
SVM Score :0.0 |
| Mammalian cytosolic thioredoxin reductase is a homodimer of 55 kDa subunit containing an essential penultimate selenocysteine residue . ^^^ |
|
| Interacting proteins: P30044 and P00441 |
Pubmed |
SVM Score :0.0 |
| Mammalian mitochondrial thioredoxin reductase is a selenoprotein that forms a homodimer of 55 kDa / subunit ; while yeast mitochondrial thioredoxin reductase is a homodimer of 37 kDa / subunit and does not contain selenocysteine . ^^^ |
|
| Interacting proteins: P30044 and P00441 |
Pubmed |
SVM Score :0.0 |
| Intracellular defense systems that protect cells from ROS induced damage include glutathione reductase ( GR ) , thioredoxin reductase ( TrxR ) , superoxide dismutase ( Sod ) , and catalase ( Cat ) . ^^^ |
|
| Interacting proteins: P30044 and P00441 |
Pubmed |
SVM Score :0.0 |
| It appears that the major mitochondrial antioxidant system is made of manganese superoxide dismutase on the one hand , and of peroxiredoxin 3 , mitochondrial thioredoxin and mitochondrial thioredoxin reductase on the other hand . ^^^ |
|
| Interacting proteins: P30044 and P00441 |
Pubmed |
SVM Score :0.0 |
| Our in vitro kinetic inhibition experiments with 4 OHEN showed that GST P 1 1 had a lower K ( 1 ) value ( 20 . 8 microM ) compared to glyceraldehyde 3 phosphate dehydrogenase ( GAPDH , 52 . 4 microM ) , P 450 reductase ( PR , 77 . 4 microM ) , pyruvate kinase ( PK , 159 microM ) , glutathione reductase ( GR , 230 microM ) , superoxide dismutase ( SOD , 448 microM ) , catalase ( 562 microM ) , GST M 1 1 ( 620 microM ) , thioredoxin reductase ( TR , 694 microM ) , and glutathione peroxidase ( GPX , 1410 microM ) . ^^^ |
|
| Interacting proteins: P30044 and P00441 |
Pubmed |
SVM Score :0.0 |
| The introduction of additional transgenes encoding Mn SOD or thioredoxin reductase in the same genetic background also failed to cause life span extension . ^^^ |
|
| Interacting proteins: P30044 and P00441 |
Pubmed |
SVM Score :0.0 |
| We studied the expression of antioxidant enzymes ( AOEs ) and related proteins manganese superoxide dismutase ( MnSOD ) , thioredoxin ( Trx ) , thioredoxin reductase ( TrxR ) , and the catalytic ( GLCL c ) and regulatory ( GLCL r ) subunits of glutamate cysteine ligase ( gamma glutamylcysteinesynthetase ) in 433 astrocytomas . ^^^ |
|
| Interacting proteins: P30044 and P00441 |
Pubmed |
SVM Score :0.0 |
| The mRNA expression of glutathione S transferase Pi , peroxiredoxin 2 , thioredoxin 2 , and glutaredoxin was elevated whereas that of peroxiredoxin 3 , metallothionein 1F , superoxide dismutase 2 , and thioredoxin reductase 1 was depressed . ^^^ |
|
| Interacting proteins: P30044 and P00441 |
Pubmed |
SVM Score :0.0 |
| Selenium deprivation caused dose dependent decreases in liver glutathione peroxidase ( 28 . 55 + / 3 . 82 mmoles / min / mg vs 34 . 68 + / 8 . 64 mmoles / min / mg ) and thioredoxin reductase ( 2 . 37 + / 1 . 25 U / mg vs 6 . 68 + / 1 . 82 U / mg ) activity , whereas superoxide dismutase activity remained constant . ^^^ |
|
| Interacting proteins: P30044 and P00441 |
Pubmed |
SVM Score :0.0 |
| To investigate the roles of essential trace element selenium and cellular antioxidative systems in human hepatocellular carcinoma , we analyzed cellular distribution of selenium and assayed cytosolic and mitochondrial superoxide dismutase , glutathione peroxidase , thioredoxin reductase , glutathione and total protein thiols in 10 control healthy subjects , 6 cases of hepatocellular carcinoma and 2 cases of normal liver adjacent to the hepatocellular carcinoma . ^^^ |
|
| Interacting proteins: P30044 and P00441 |
Pubmed |
SVM Score :0.0 |
| In this study we have examined the tissue levels of endogenous anti oxidant proteins ( superoxide dismutase , glutathione peroxidase , thioredoxin reductase and thioredoxin ) and the level of lipid and protein oxidation in placental samples from normal and pre eclamptic pregnancies . ^^^ |
|
| Interacting proteins: P30044 and P00441 |
Pubmed |
SVM Score :0.0 |
| Anti oxidant enzyme activities of superoxide dismutase , glutathione peroxidase and thioredoxin reductase , thioredoxin concentrations , lipid and protein oxidation levels were measured in placentae of pregnancies complicated by asthma and compared to uncomplicated , non asthmatic pregnancies . ^^^ The activities of the anti oxidant proteins superoxide dismutase ( 2 . 17+ / 0 . 09 units / mg protein versus 1 . 67+ / 0 . 09 units / mg protein , P=0 . 014 ) and thioredoxin reductase ( 54 . 0+ / 6 . 9 units / mg protein versus 28 . 7+ / 6 . 0 units / mg protein , P=0 . 009 ) were significantly increased in the presence of maternal asthma . ^^^ |
|
| Interacting proteins: P30044 and P00441 |
Pubmed |
SVM Score :0.0 |
| The expression of antioxidant enzymes and related proteins ( AOEs ) , manganese superoxide dismutase ( MnSOD ) , thioredoxin ( Trx ) , thioredoxin reductase ( TrxR ) and gammaglutamylcysteine synthetase catalytic and regulatory subunits ( GLCL C and GLCL R ) , was studied in 85 oligodendroglial tumors . ^^^ |
|
| Interacting proteins: P30044 and P00441 |
Pubmed |
SVM Score :0.0 |
| In addition , multiple genes involved in defense against reactive oxygen species ( ROS ) produced by the phagocyte were predicted with high expressivity , which included alkylhydroperoxide reductase ( ahpC ) , catalase ( katG ) , superoxide dismutase ( sodF ) , thioredoxin , thioredoxin reductase , glutathione peroxidase , and peptide methionine sulfoxide reductase , suggesting that combating against ROS is essential for survival of N . farcinica in host cells . ^^^ |
|
| Interacting proteins: P30044 and P00441 |
Pubmed |
SVM Score :0.0 |
| Placental tissues were homogenized and assayed for lipid peroxides , protein carbonyls , superoxide dismutase , glutathione peroxidase , and thioredoxin reductase . ^^^ There was no significant increase in lipid or protein oxidation after treatment with L NAME , and no difference was found in the activities of superoxide dismutase , glutathione peroxidase , and thioredoxin reductase . ^^^ |
|