Interacting proteins: O95997 and P06493 |
Pubmed |
SVM Score :0.0 |
Immunodepletion and in vitro phosphorylation experiments , together with the use of a specific inhibitor , indicate that Cdc 2 is the kinase that phosphorylates hPTTG . ^^^ |
|
Interacting proteins: O95997 and P06493 |
Pubmed |
SVM Score :0.0 |
Using Xenopus egg extracts , we demonstrate that high CDC 2 activity inhibits anaphase but not securin degradation . ^^^ |
|
Interacting proteins: O95997 and P06493 |
Pubmed |
SVM Score :0.0 |
Here we show that homologue disjunction in mouse oocytes is dependent on proteolysis of the separase inhibitor securin and the Cdk 1 regulatory sub unit cyclin B 1 . ^^^ |
|
Interacting proteins: O95997 and P06493 |
Pubmed |
SVM Score :0.0 |
Indeed , sister chromatid separation but not securin degradation is inhibited by constitutively active cyclin dependent kinase 1 ( Cdk 1 ) and can be rescued solely by preventing phosphorylation of separase . ^^^ |
|
Interacting proteins: O95997 and P06493 |
Pubmed |
SVM Score :0.0 |
Anaphase topsy turvy : Cdk 1 a securin , separase a CKI . ^^^ In vertebrates Cdk 1 dependent inhibition of separase represents a second , securin independent branch of anaphase regulation . ^^^ |
|
Interacting proteins: O95997 and P06493 |
Pubmed |
SVM Score :0.0 |
Separase not only triggers anaphase of meiosis 1 by proteolytic cleavage of cohesin on chromosome arms , but in vitro vertebrate separase also acts as a direct inhibitor of cyclin dependent kinase 1 ( Cdk 1 ) on liberation from the inhibitory protein , securin . ^^^ |
|
Interacting proteins: O95997 and P06493 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: O95997 and P06493 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: O95997 and P06493 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: O95997 and P06493 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: O95997 and P06493 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: O95997 and P06493 |
Pubmed |
SVM Score :0.0 |
NA |
|