| Interacting proteins: O95835 and P06493 |
Pubmed |
SVM Score :0.7455748 |
| In mammalian cells , LATS 1 is phosphorylated in a cell cycle dependent manner and complexes with CDC 2 in early mitosis . 0.7455748^^^ |
|
| Interacting proteins: O95835 and P06493 |
Pubmed |
SVM Score :0.5920556 |
| The mammalian LATS 1 protein was previously shown to bind to CDC 2 , suggesting that LATS 1 may modulate G ( 2 ) / M cell cycle progression by affecting CDC 2 activity . 0.5920556^^^ |
|
| Interacting proteins: O95835 and P06493 |
Pubmed |
SVM Score :0.63167059 |
| Our previous studies have shown that inactivation of Drosophila lats leads to up regulation of cyclin A in the fly , and the human LATS 1 protein associates with CDC 2 in early mitosis in HeLa cells , suggesting that the lats gene family may negatively regulate cell proliferation by modulating CDC2 / Cyclin A activity . 0.63167059^^^ |
|
| Interacting proteins: O95835 and P06493 |
Pubmed |
SVM Score :0.0 |
| Furthermore , h warts is specifically phosphorylated in cells at mitotic phase , most likely by Cdc 2 kinase . ^^^ |
|
| Interacting proteins: O95835 and P06493 |
Pubmed |
SVM Score :0.0 |
| NA |
|