| Interacting proteins: O95049 and O95832 |
Pubmed |
SVM Score :0.0 |
| ZO 1 , ZO 2 , and ZO 3 bound to the COOH terminal YV sequence of claudin 1 to 8 through their PDZ 1 domains in vitro . ^^^ Then , claudin 1 or 2 was transfected into L fibroblasts , which express ZO 1 but not ZO 2 or ZO 3 . ^^^ |
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| Interacting proteins: O95049 and O95832 |
Pubmed |
SVM Score :0.0 |
| We found that the 6th and 8th PDZ domains of PATJ can interact with the carboxyl termini of zona occludens 3 ( ZO 3 ) and claudin 1 , respectively . ^^^ |
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| Interacting proteins: O95049 and O95832 |
Pubmed |
SVM Score :0.0 |
| Incubation of cells with DETA NONOate or cytomix decreased epithelial barrier function , decreased expression of ZO 1 mRNA , decreased expression of ZO 1 , ZO 3 , and occludin protein , and increased expression of claudin 1 protein . ^^^ |
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| Interacting proteins: O95049 and O95832 |
Pubmed |
SVM Score :0.0 |
| While molecular expression of junctional adhesion molecule ( JAM ) , ZO 2 , ZO 3 , claudin 2 and claudin 3 were unaltered , ZO 1 , occludin , and claudin 4 were all up regulated ( 1 . 6 , 1 . 6 , 2 . 4 fold , respectively ; P < 0 . 001 0 . 01 ) and claudin 1 down regulated ( 2 . 5 fold ; P < 0 . 05 ) by trans 10 , cis 12 CLA , which may underpin its effects on tight junction function and paracellular Ca transport . ^^^ |
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