| Interacting proteins: O95644 and P17947 |
Pubmed |
SVM Score :0.57453207 |
| RANKL induced NFATc 1 forms a complex with PU . 1 in nuclei of osteoclasts following the nuclear accumulation of NFATc 1 phosphorylated by the activated p 38 MAP kinase . 0.57453207^^^ |
|
| Interacting proteins: O95644 and P17947 |
Pubmed |
SVM Score :0.0 |
| NFATc 1 expression results in the activation of the OSCAR promoter , which was found to be further enhanced by co expression of PU . 1 and microphthalmia associated transcription factor ( MITF ) . ^^^ |
|
| Interacting proteins: O95644 and P17947 |
Pubmed |
SVM Score :0.0 |
| Furthermore , NFATc 1 synergistically activates an OSCAR reporter construct together with microphthalmia transcription factor and PU . 1 , transcription factors previously shown to be critical for osteoclast differentiation . ^^^ |
|
| Interacting proteins: O95644 and P17947 |
Pubmed |
SVM Score :0.0 |
| In Jurkat T cells , EGR 1 but not Sp 1 acts as a potent coactivator for IL 2 transcription , and in combination with NFATc , EGR 1 increases transcription of an IL 2 reporter construct 200 fold . ^^^ |
|
| Interacting proteins: O95644 and P17947 |
Pubmed |
SVM Score :0.0 |
| Subsequently , semiquantitative RT PCR and gel shift assays with nuclear extracts were performed to analyze the effects of NO on IL 2 mRNA expression and on the activity of the dominant regulating transcription factors Sp 1 , EGR 1 , and NFATc . ^^^ |
|
| Interacting proteins: O95644 and P17947 |
Pubmed |
SVM Score :0.0 |
| Moreover , we also show that Egr 1 forms a complex with other redox sensitive transcription factors ( e . g . , AP 1 , AP 2 , NFATc , Sp 1 , PAX 5 , MTF 1 , c Myb , and CREB ) in rat duodenal mucosa and that cysteamine enhances the formation of these complexes . ^^^ |
|
| Interacting proteins: O95644 and P17947 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O95644 and P17947 |
Pubmed |
SVM Score :0.0 |
| NA |
|