| Interacting proteins: Q9C0C2 and O95271 |
Pubmed |
SVM Score :0.0 |
| The telomeric poly ( ADP ribose ) polymerase , tankyrase 1 , contains multiple binding sites for telomeric repeat binding factor 1 ( TRF 1 ) and a novel acceptor , 182 kDa tankyrase binding protein ( TAB 182 ) . ^^^ Here we identify TAB 182 , a novel tankyrase 1 binding protein of 182 kDa . ^^^ TAB 182 coimmunoprecipitates with tankyrase 1 from human cells and serves as an acceptor of poly ( ADP ribosyl ) ation by tankyrase 1 in vitro . ^^^ Like TRF 1 , TAB 182 binds to the ankyrin domain ( comprising 24 ankyrin repeats ) of tankyrase 1 . ^^^ |
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| Interacting proteins: Q9C0C2 and O95271 |
Pubmed |
SVM Score :0.0 |
| Tankyrase 1 and 2 are closely related poly ( ADP ribose ) polymerases that use an ankyrin repeat domain to bind diverse proteins , including TRF ( telomere repeat binding factor ) 1 , IRAP ( insulin responsive aminopeptidase ) , and TAB 182 ( 182 kDa tankyrase binding protein ) . ^^^ |
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