| Interacting proteins: O75553 and Q00535 |
Pubmed |
SVM Score :0.0 |
| On the other hand , the gradient of corticogenesis is directed from outside to inside in all reptiles studied , as well as in mice that are deficient in reelin , Dab 1 , as well as cyclin dependent kinase 5 ( Cdk 5 ) and p 35 . ^^^ |
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| Interacting proteins: O75553 and Q00535 |
Pubmed |
SVM Score :0.0 |
| To explore the possibility that Cdk 5 influences the Reelin pathway , we sought to determine whether Dab 1 is a substrate for Cdk 5 . ^^^ Here we show that Cdk 5 phosphorylates Dab 1 on serine 491 in vitro and in vivo , independently of Reelin signaling . ^^^ We also show that ectopic neurons in Cdk 5 deficient mice exhibit reduced levels of Reelin signaling during later stages of cortical development , although Cdk 5 is not required for Reelin induced tyrosine phosphorylation of Dab 1 . ^^^ |
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| Interacting proteins: O75553 and Q00535 |
Pubmed |
SVM Score :0.0 |
| GSK 3beta and CDK 5 activity increased in Dab 1 deficient mice , independent of ApoE levels . ^^^ |
|
| Interacting proteins: O75553 and Q00535 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O75553 and Q00535 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O75553 and Q00535 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O75553 and Q00535 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O75553 and Q00535 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O75553 and Q00535 |
Pubmed |
SVM Score :0.0 |
| NA |
|