Moreover , we demonstrate that endogenous E2F6 and polycomb group proteins , including RYBP , Ring 1 , MEL 18 , mph 1 , and the oncoprotein Bmi 1 , associate with one another . ^^^
Investigation of the relationship between E2F6 and RING 1 by immunofluorescence and confocal analysis , in HL cell lines and paraffin sections , revealed co expression of both proteins in the same tumour cells . ^^^