| Interacting proteins: O75365 and P42224 |
Pubmed |
SVM Score :0.0 |
| Furthermore , these PRL R mutants mediated reduced Stat 1 binding to the IRF 1 GAS . ^^^ |
|
| Interacting proteins: O75365 and P42224 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O75365 and P42224 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O75365 and P42224 |
Pubmed |
SVM Score :0.0 |
| This selective activation of STAT 5 by prolactin was also observed in COS 7 cells cotransfected with the long form of the mouse prolactin receptor ( PRL R ) and expression vectors for STAT 1 , STAT 3 , STAT 5 and STAT 6 . ^^^ |
|
| Interacting proteins: O75365 and P42224 |
Pubmed |
SVM Score :0.0 |
| These results demonstrate a novel interaction of OAS with the PRL R and suggest a role for OAS in modulating Stat 1 mediated signaling to an immediate early gene promoter . ^^^ |
|
| Interacting proteins: O75365 and P42224 |
Pubmed |
SVM Score :0.0 |
| PRL R signal transduction is mediated by a complex array of signaling molecules of which JAK 2 , Stat 1 and Stat 5 pathway have been well studied . ^^^ |
|
| Interacting proteins: O75365 and P42224 |
Pubmed |
SVM Score :0.0 |
| Here , we examine different mutants of the PRLR with respect to their ability to associate and activate the kinase Jak 2 and the transcription factor Stat 1 . ^^^ |
|