| Interacting proteins: O75081 and O43439 |
Pubmed |
SVM Score :0.0 |
| We characterize two human MTG 8 related genes , MTGR 1 and MTGR 2 ( HGMW approved symbols CBFA2T2 and CBFA2T3 ) . ^^^ |
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| Interacting proteins: O75081 and O43439 |
Pubmed |
SVM Score :0.0 |
| The genomic structure of MTGR 1 is highly similar to those of other MTG 8 family genes , MTG 8 and MTG 16 . ^^^ |
|
| Interacting proteins: O75081 and O43439 |
Pubmed |
SVM Score :0.0 |
| The transcriptional repression of growth factor independent 1 ( GFI 1 ) , a previously characterized ETO effector zinc finger protein , was shown to be enhanced by CBFA2T1 , but to a lesser extent by CBFA2T2 and CBFA2T3 . ^^^ |
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| Interacting proteins: O75081 and O43439 |
Pubmed |
SVM Score :0.0 |
| The structural analysis of the cDNAs showed that AML 1 was fused to a novel gene named MTG 16 ( Myeloid Translocation Gene on chromosome 16 ) which shows high homology to MTG 8 ( ETO / CDR ) and MTGR 1 . ^^^ |
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| Interacting proteins: O75081 and O43439 |
Pubmed |
SVM Score :0.0 |
| The eight twenty one ( ETO ) homologues , represented by ETO , myeloid transforming gene related protein 1 ( MTGR 1 ) and myeloid transforming gene chromosome 16 ( MTG 16 ) , are nuclear repressor proteins . ^^^ Similarly , the chimeric oncoprotein AML 1 ETO interacted with both MTGR 1 and MTG 16 . ^^^ |
|
| Interacting proteins: O75081 and O43439 |
Pubmed |
SVM Score :0.0 |
| The Eight twenty one ( ETO ) homologues are nuclear repressor proteins including ETO , myeloid transforming gene related protein 1 ( MTGR 1 ) , and myeloid transforming gene chromosome 16 ( MTG 16 ) . ^^^ Our results showed MTGR 1 and MTG 16 to be ubiquitously expressed in leukemic cell lines , whereas expression of ETO was observed only in an erythroleukemic cell line . ^^^ The MTGR 1 and MTG 16 proteins decreased during all trans retinoic acid , but not vitamin D ( 3 ) induced differentiation of leukemic cells . ^^^ |
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| Interacting proteins: O75081 and O43439 |
Pubmed |
SVM Score :0.0 |
| The Nervy homology 2 ( NHR 2 ) domain in ETO mediates oligomerization and AML1 / ETO ' s interactions with ETO , MTGR 1 , and MTG 16 , and with the corepressor molecules mSin3A and HDAC 1 and HDAC 3 . ^^^ Oligomerization is also required for AML1 / ETO ' s interactions with ETO , MTGR 1 , and MTG 16 , but not with other corepressor molecules . . ^^^ |
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| Interacting proteins: O75081 and O43439 |
Pubmed |
SVM Score :0.0 |
| NA |
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