| Interacting proteins: O60542 and Q9GZZ7 |
Pubmed |
SVM Score :0.70853607 |
| We have shown that persephin binds efficiently only to GFR alpha 4 , and labelled persephin is effectively displaced from cells expressing GFR alpha 4 by persephin but not by GDNF or neurturin . 0.70853607^^^ |
|
| Interacting proteins: O60542 and Q9GZZ7 |
Pubmed |
SVM Score :1.0141092 |
| A candidate for such a gene is glial cell line derived neurotrophic factor receptor alpha 4 ( GFRA 4 ) , which encodes a cell surface bound co receptor ( GFR alpha 4 ) required for interaction of RET with its ligand persephin . 1.0141092^^^ |
|
| Interacting proteins: O60542 and Q9GZZ7 |
Pubmed |
SVM Score :0.0 |
| We describe the cloning and characterization of a mammalian persephin receptor GFRalpha 4 . ^^^ Although the newly characterized mammalian GFRalpha 4 receptor is structurally divergent from previously characterized GFRalpha family members , we suggest that it is a mammalian orthologue of the chicken persephin receptor . ^^^ |
|
| Interacting proteins: O60542 and Q9GZZ7 |
Pubmed |
SVM Score :0.0 |
| When grown as spheres , these cells expressed mRNAs for GDNF , persephin , GFR alpha 2 , GFR alpha 4 ( neurturin receptor ) , and Ret . ^^^ |
|
| Interacting proteins: O60542 and Q9GZZ7 |
Pubmed |
SVM Score :0.0 |
| Ablation of persephin receptor glial cell line derived neurotrophic factor family receptor alpha 4 impairs thyroid calcitonin production in young mice . ^^^ |
|
| Interacting proteins: O60542 and Q9GZZ7 |
Pubmed |
SVM Score :0.0 |
| GDNF binds preferentially to GFR alpha 1 , NTN GFR alpha 2 , ART GRF alpha 3 , and PSP GFR alpha 4 as a co receptor to activate Ret . ^^^ |
|
| Interacting proteins: O60542 and Q9GZZ7 |
Pubmed |
SVM Score :0.0 |
| Unlabeled PSPN displaces ( 125 ) 1 PSPN from GFRA 4 transfected cells , which express endogenous Ret . ^^^ PSPN can be specifically cross linked to mammalian GFRalpha 4 and Ret , and is able to promote autophosphorylation of Ret in GFRA 4 transfected cells . ^^^ PSPN , but not other GDNF family ligands , promotes the survival of cultured sympathetic neurons microinjected with GFRA 4 . ^^^ |
|
| Interacting proteins: O60542 and Q9GZZ7 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O60542 and Q9GZZ7 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O60542 and Q9GZZ7 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O60542 and Q9GZZ7 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O60542 and Q9GZZ7 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O60542 and Q9GZZ7 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9GZZ7 and O60542 |
Pubmed |
SVM Score :0.70853607 |
| We have shown that persephin binds efficiently only to GFR alpha 4 , and labelled persephin is effectively displaced from cells expressing GFR alpha 4 by persephin but not by GDNF or neurturin . 0.70853607^^^ |
|
| Interacting proteins: Q9GZZ7 and O60542 |
Pubmed |
SVM Score :1.0141092 |
| A candidate for such a gene is glial cell line derived neurotrophic factor receptor alpha 4 ( GFRA 4 ) , which encodes a cell surface bound co receptor ( GFR alpha 4 ) required for interaction of RET with its ligand persephin . 1.0141092^^^ |
|
| Interacting proteins: Q9GZZ7 and O60542 |
Pubmed |
SVM Score :0.0 |
| GDNF binds preferentially to GFR alpha 1 , NTN GFR alpha 2 , ART GRF alpha 3 , and PSP GFR alpha 4 as a co receptor to activate Ret . ^^^ |
|
| Interacting proteins: Q9GZZ7 and O60542 |
Pubmed |
SVM Score :0.0 |
| When grown as spheres , these cells expressed mRNAs for GDNF , persephin , GFR alpha 2 , GFR alpha 4 ( neurturin receptor ) , and Ret . ^^^ |
|
| Interacting proteins: Q9GZZ7 and O60542 |
Pubmed |
SVM Score :0.0 |
| We describe the cloning and characterization of a mammalian persephin receptor GFRalpha 4 . ^^^ Although the newly characterized mammalian GFRalpha 4 receptor is structurally divergent from previously characterized GFRalpha family members , we suggest that it is a mammalian orthologue of the chicken persephin receptor . ^^^ |
|
| Interacting proteins: Q9GZZ7 and O60542 |
Pubmed |
SVM Score :0.0 |
| Ablation of persephin receptor glial cell line derived neurotrophic factor family receptor alpha 4 impairs thyroid calcitonin production in young mice . ^^^ |
|
| Interacting proteins: Q9GZZ7 and O60542 |
Pubmed |
SVM Score :0.0 |
| Unlabeled PSPN displaces ( 125 ) 1 PSPN from GFRA 4 transfected cells , which express endogenous Ret . ^^^ PSPN can be specifically cross linked to mammalian GFRalpha 4 and Ret , and is able to promote autophosphorylation of Ret in GFRA 4 transfected cells . ^^^ PSPN , but not other GDNF family ligands , promotes the survival of cultured sympathetic neurons microinjected with GFRA 4 . ^^^ |
|
| Interacting proteins: Q9GZZ7 and O60542 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9GZZ7 and O60542 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9GZZ7 and O60542 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9GZZ7 and O60542 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9GZZ7 and O60542 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9GZZ7 and O60542 |
Pubmed |
SVM Score :0.0 |
| NA |
|