| Interacting proteins: O60500 and O14936 |
Pubmed |
SVM Score :0.0 |
| Nephrin forms a complex with adherens junction proteins and CASK in podocytes and in Madin Darby canine kidney cells expressing nephrin . ^^^ Using co immunoprecipitation and pull down assays we show here that nephrin forms a multiprotein complex with cadherins and p 120 catenin and with three scaffolding proteins , ZO 1 , CD2AP , and CASK , in kidney glomeruli and when expressed in Madin Darby canine kidney cells . ^^^ CASK was identified as a novel binding partner of nephrin by mass spectrometry and was localized to podocytes in the glomerulus . ^^^ |
|
| Interacting proteins: O60500 and O14936 |
Pubmed |
SVM Score :0.0 |
| Nephrin specifically pulled down six proteins from glomerular lysates , MAGI 2 / S SCAM ( membrane associated guanylate kinase inverted 2 / synaptic scaffolding molecule ) , IQGAP 1 ( IQ motif containingGTPase activatingprotein 1 ) , CASK ( calcium / calmodulin dependent serine protein kinase ) , alpha actinin , alphaII spectrin , and betaII spectrin . ^^^ Cell junction associated proteins IQGAP 1 , MAGI 2 , CASK , spectrins , and alpha actinin are components of the nephrin multiprotein complex . ^^^ |
|
| Interacting proteins: O60500 and O14936 |
Pubmed |
SVM Score :0.0 |
| NA |
|