| Interacting proteins: O60462 and Q99985 |
Pubmed |
SVM Score :0.0 |
| Neuropilin 2 , a novel member of the neuropilin family , is a high affinity receptor for the semaphorins Sema E and Sema 4 but not Sema 3 . ^^^ Unlike neuropilin 1 , which binds with high affinity to the three structurally related semaphorins Sema 3 , Sema E , and Sema 4 , neuropilin 2 shows high affinity binding only to Sema E and Sema 4 , not Sema 3 . ^^^ |
|
| Interacting proteins: O60462 and Q99985 |
Pubmed |
SVM Score :0.0 |
| Neuropilin 1 and neuropilin 2 show specificity in binding to different class 3 semaphorins , including Sema 3 , Sema E , and Sema 4 , suggesting that the specificity of action of these semaphorins is dictated by the complement of neuropilins expressed by responsive neurons . ^^^ These results support the idea that in sympathetic axons , the Sema 3 signal is mediated predominantly by neuropilin 1 oligomers , the Sema 4 signal by neuropilin 2 oligomers , and the Sema E signal by neuropilin 1 and 2 , either as homo or heterooligomers . . ^^^ |
|
| Interacting proteins: O60462 and Q99985 |
Pubmed |
SVM Score :0.0 |
| SemA and SemE seem to have a newly discovered protein antagonist capacity at NP 1 receptors , whereas they act as agonists at receptors containing NP 2 . . ^^^ |
|
| Interacting proteins: O60462 and Q99985 |
Pubmed |
SVM Score :0.0 |
| Following up on that initial observation , we have now used real time quantitative reverse transcription polymerase chain reaction to demonstrate induction of genes encoding neuropilin 1 ( NP 1 ) , which , like NP 2 , serves as a coreceptor for members of the class 3 semaphorin family of axonal guidance molecules and of five of the six known class 3 semaphorins ( Sema3A , Sema3B , Sema3C , Sema3E , and Sema3F , but not Sema3D ) in crushed or transected sciatic nerves . . ^^^ |
|
| Interacting proteins: O60462 and Q99985 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O60462 and Q99985 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q99985 and O60462 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q99985 and O60462 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q99985 and O60462 |
Pubmed |
SVM Score :0.0 |
| Neuropilin 2 , a novel member of the neuropilin family , is a high affinity receptor for the semaphorins Sema E and Sema 4 but not Sema 3 . ^^^ Unlike neuropilin 1 , which binds with high affinity to the three structurally related semaphorins Sema 3 , Sema E , and Sema 4 , neuropilin 2 shows high affinity binding only to Sema E and Sema 4 , not Sema 3 . ^^^ |
|
| Interacting proteins: Q99985 and O60462 |
Pubmed |
SVM Score :0.0 |
| Neuropilin 1 and neuropilin 2 show specificity in binding to different class 3 semaphorins , including Sema 3 , Sema E , and Sema 4 , suggesting that the specificity of action of these semaphorins is dictated by the complement of neuropilins expressed by responsive neurons . ^^^ These results support the idea that in sympathetic axons , the Sema 3 signal is mediated predominantly by neuropilin 1 oligomers , the Sema 4 signal by neuropilin 2 oligomers , and the Sema E signal by neuropilin 1 and 2 , either as homo or heterooligomers . . ^^^ |
|
| Interacting proteins: Q99985 and O60462 |
Pubmed |
SVM Score :0.0 |
| Following up on that initial observation , we have now used real time quantitative reverse transcription polymerase chain reaction to demonstrate induction of genes encoding neuropilin 1 ( NP 1 ) , which , like NP 2 , serves as a coreceptor for members of the class 3 semaphorin family of axonal guidance molecules and of five of the six known class 3 semaphorins ( Sema3A , Sema3B , Sema3C , Sema3E , and Sema3F , but not Sema3D ) in crushed or transected sciatic nerves . . ^^^ |
|
| Interacting proteins: Q99985 and O60462 |
Pubmed |
SVM Score :0.0 |
| SemA and SemE seem to have a newly discovered protein antagonist capacity at NP 1 receptors , whereas they act as agonists at receptors containing NP 2 . . ^^^ |
|