Interacting proteins: O60244 and O43513 |
Pubmed |
SVM Score :0.0 |
Cloning of genes encoding CRSP subunits reveals that CRSP 33 is a homologue of the yeast mediator subunit Med 7 , whereas CRSP 150 contains a domain conserved in yeast mediator subunit Rgr 1 . ^^^ |
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Interacting proteins: O60244 and O43513 |
Pubmed |
SVM Score :0.0 |
A multiprotein complex isolated from murine cells is identified as a counterpart of the yeast Mediator of transcriptional regulation on the basis of the following : homologs of two subunits of yeast Mediator , Srb 7 and Med 7 , copurify with the complex ; peptide sequencing reveals , in addition , homologs of the yeast Mediator subunits Rgr 1 and Med 6 ; as with yeast Mediator , the mouse complex binds to the RNA polymerase 2 C terminal domain ( CTD ) and stimulates phosphorylation of the CTD by TFIIH . ^^^ |
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Interacting proteins: O60244 and O43513 |
Pubmed |
SVM Score :0.0 |
Five of these Mediator subunits have been identified as the S . pombe homologs to Rgr 1 , Srb 4 , Med 7 , and Nut 2 found in S . cerevisiae and the gene product of a previously uncharacterized open reading frame , PMC 2 , with no clear homologies to any described protein . ^^^ |
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