| We show that the hRAD 21 subunit of the cohesin complex directly interacts with the ATPase subunit SNF2h . ^^^ Mapping of hRAD 21 , SNF2h and Mi 2 binding sites by chromatin immunoprecipitation experiments reveals the specific association of these three proteins with human DNA elements containing Alu sequences . ^^^ Finally , we present evidence pointing to a role for the ATPase activity of SNF2h in the loading of hRAD 21 on chromatin . . ^^^ |