| Interacting proteins: O95944 and O43914 |
Pubmed |
SVM Score :0.0 |
| NA |
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| Interacting proteins: O95944 and O43914 |
Pubmed |
SVM Score :0.0 |
| The charged amino acid lysine in the transmembrane region may be involved in the association of NKp 44 with the signal transducing molecule killer activating receptor associated polypeptide ( KARAP ) / DAP12 . ^^^ |
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| Interacting proteins: O95944 and O43914 |
Pubmed |
SVM Score :0.0 |
| NKp 44 triggers NK cell activation through DAP 12 association that is not influenced by a putative cytoplasmic inhibitory sequence . ^^^ Our results demonstrate that surface expression and NK cell activation by NKp 44 is mediated through noncovalent association with the immunoreceptor tyrosine based activation motif containing protein , DAP 12 . ^^^ Physical linkage to DAP 12 requires lysine 183 in the NKp 44 transmembrane domain . ^^^ In summary , all activating properties and surface expression of NKp 44 are mediated through its association with DAP 12 , and the putative ITIM in the NKp 44 cytoplasmic domain does not appear to attenuate activating function . . ^^^ |
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| Interacting proteins: O95944 and O43914 |
Pubmed |
SVM Score :0.0 |
| Decreased expression of DAP 12 in NK cells from the patients was accompanied by increased expression of ADAR 1 ( adenosine deaminase that acts on RNA transcripts ) and by decreased expression of NKp 44 . ^^^ |
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| Interacting proteins: O95944 and O43914 |
Pubmed |
SVM Score :0.0 |
| The novel activation receptor NKp 44 and its adaptor , DAP 12 , NKG2D , and constitutively phosphorylated ERK 2 may be associated with the enhanced cytotoxicity of KHYG 1 . ^^^ |
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