| Interacting proteins: O15553 and O43586 |
Pubmed |
SVM Score :0.67550738 |
| We now show that proline serine threonine phosphatase interacting protein [ PSTPIP 1 , or CD 2 binding protein 1 ( CD2BP1 ) ] , a tyrosine phosphorylated protein involved in cytoskeletal organization , also interacts with pyrin . 0.67550738^^^ |
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| Interacting proteins: O15553 and O43586 |
Pubmed |
SVM Score :0.0 |
| These connections occur , at least in part , through the direct interaction of the pyrin / marenostrin protein with two cytosolic protein adaptors : ASC ( also called PyCARD or Tms 1 ) and PSTPIP ( also called CD2BP1 ) . ^^^ |
|
| Interacting proteins: O15553 and O43586 |
Pubmed |
SVM Score :0.0 |
| They demonstrated an interaction between pyrin and proline serine threonine phosphatase interacting protein 1 ( PSTPIP 1 ) , the protein involved in PAPA , and thus revealed a biochemical pathway common to both FMF and PAPA . . ^^^ |
|
| Interacting proteins: O15553 and O43586 |
Pubmed |
SVM Score :0.0 |
| PSTPIP 1 , mutated in the syndrome of pyogenic arthritis with pyoderma gangrenosum and acne , interacts both with pyrin and a protein tyrosine phosphatase to regulate innate and adaptive immune responses . ^^^ |
|
| Interacting proteins: O15553 and O43586 |
Pubmed |
SVM Score :0.0 |
| Currently , the database contains 291 sequence variants in related genes ( MEFV , TNFRSF1A , MVK , CARD 15 , PSTPIP 1 , and CIAS 1 ) , consisting of published data and personal communications , which has revealed or refined the preferential mutational sites for each gene . ^^^ |
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