Interacting proteins: P30086 and O43318 |
Pubmed |
SVM Score :1.0265747 |
RKIP has been shown to disrupt the Raf 1 MEK1 / 2 [ mitogen activated protein kinase ERK ( extracellular signal regulated kinase ) kinase 1 / 2 ] ERK1 / 2 and NF kappaB signaling pathways , via physical interaction with Raf 1 MEK1 / 2 and NF kappaB inducing kinase or transforming growth factor beta activated kinase 1 , respectively , thereby abrogating the survival and antiapoptotic properties of these signaling pathways . 1.0265747^^^ |
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Interacting proteins: P30086 and O43318 |
Pubmed |
SVM Score :0.0 |
Raf kinase inhibitor protein interacts with NF kappaB inducing kinase and TAK 1 and inhibits NF kappaB activation . ^^^ RKIP physically interacted with four kinases of the NF kappaB activation pathway , NF kappaB inducing kinase , transforming growth factor beta activated kinase 1 , IKKalpha , and IKKbeta . ^^^ |
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