| Interacting proteins: P43146 and O43255 |
Pubmed |
SVM Score :0.0 |
| Independent studies have shown that Sina and its highly related mammalian homologues Siah 1 and Siah 2 bind to the DCC ( deleted in colorectal cancer ) protein and promote its proteolysis via the ubiquitin proteasome pathway . ^^^ |
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| Interacting proteins: P43146 and O43255 |
Pubmed |
SVM Score :0.0 |
| While previous studies implicate Siah 2 in the regulation of TRAF 2 , Vav 1 , OBF 1 , and DCC , we find that a variety of responses mediated by these proteins are unaffected by loss of Siah 2 . ^^^ |
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