| Interacting proteins: O15467 and P51685 |
Pubmed |
SVM Score :1.0776103 |
| We report chemotaxis and competitive binding studies that show LEC binds to and activates CCR 1 and CCR 8 transfected HEK 293 cells . 1.0776103^^^ |
|
| Interacting proteins: O15467 and P51685 |
Pubmed |
SVM Score :0.0 |
| LEC has been shown to chemoattract monocytes , lymphocytes , and polymorphonuclear leukocytes ( PMNs ) by its binding to CCR 1 and CCR 8 chemokine receptors . ^^^ |
|
| Interacting proteins: O15467 and P51685 |
Pubmed |
SVM Score :0.0 |
| BX 471 ( R N [ 5 chloro 2 [ 2 [ 4 ( 4 fluorophenyl ) methyl ] 2 methyl 1 piperazinyl ] 2 oxoethoxy ] phenyl ] urea hydrochloric acid salt ) , a CCR 1 antagonist , inhibits angiogenic properties of CCL 16 , whereas blocking of CCR 8 or desensitizing CCR 2 , which are both well known receptors for CCL 16 , did not abolish endothelial activation . ^^^ |
|
| Interacting proteins: O15467 and P51685 |
Pubmed |
SVM Score :0.0 |
| The binding of LEC to CCR 8 was much less significant . ^^^ |
|
| Interacting proteins: O15467 and P51685 |
Pubmed |
SVM Score :0.0 |
| NA |
|