| Interacting proteins: O15400 and P51809 |
Pubmed |
SVM Score :0.0 |
| Syntaxin 7 and VAMP 7 are soluble N ethylmaleimide sensitive factor attachment protein receptors required for late endosome lysosome and homotypic lysosome fusion in alveolar macrophages . ^^^ These studies indicate that : 1 ) fusion along the endocytic pathway is a highly regulated process , and 2 ) two SNARE molecules , Syntaxin 7 and human VAMP 7 , are involved in fusion of vesicles in the late endocytic pathway in alveolar macrophages . . ^^^ |
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| Interacting proteins: O15400 and P51809 |
Pubmed |
SVM Score :0.0 |
| Syntaxin 7 complexes with mouse Vps10p tail interactor 1b , syntaxin 6 , vesicle associated membrane protein ( VAMP ) 8 , and VAMP 7 in b 16 melanoma cells . ^^^ These polypeptides corresponded to Syntaxin 7 , Syntaxin 6 , mouse Vps10p tail interactor 1b ( mVti1b ) , alpha synaptosome associated protein ( SNAP ) , vesicle associated membrane protein ( VAMP ) 8 , VAMP 7 , and the protein phosphatase 1M regulatory subunit . ^^^ Based on these and data reported previously , we propose that Syntaxin 7 / mVti1b / Syntaxin 6 may form discrete SNARE complexes with either VAMP 7 or VAMP 8 to regulate fusion events within the late endosomal pathway and that these events may play a critical role in melanogenesis . . ^^^ |
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| Interacting proteins: O15400 and P51809 |
Pubmed |
SVM Score :0.0 |
| Syntaxin 7 , syntaxin 8 , Vti 1 and VAMP 7 ( vesicle associated membrane protein 7 ) form an active SNARE complex for early macropinocytic compartment fusion in Dictyostelium discoideum . ^^^ The syntaxin 7 complex contains two co t SNAREs [ Vti 1 ( Vps10p tail interactor 1 ) and syntaxin 8 ] and a 5 SNARE [ VAMP 7 ( vesicle associated membrane protein 7 ) ] ( where t SNAREs are SNAREs of the target compartment and 5 SNAREs are SNAREs present in donor vesicles ) . ^^^ In endosomes and in vitro , syntaxin 7 , Vti 1 and syntaxin 8 form a complex that is able to bind VAMP 7 . ^^^ The lysosomal content of syntaxin 7 , Vti 1 , syntaxin 8 and VAMP 7 is low compared with that in endosomes , implying a highly active recycling or retention mechanism . ^^^ A likely model is that VAMP 7 is a 5 SNARE present on vesicles carrying lysosomal enzymes , and that the syntaxin 7 Vti 1 syntaxin 8 t SNARE complex is associated with incoming endocytic material . . ^^^ |
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| Interacting proteins: O15400 and P51809 |
Pubmed |
SVM Score :0.0 |
| Co immunoprecipitation demonstrated separate syntaxin 7 complexes with either VAMP 7 or VAMP 8 in solubilized rat liver membranes . ^^^ |
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| Interacting proteins: O15400 and P51809 |
Pubmed |
SVM Score :0.0 |
| NA |
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